anti-Rat (Rattus) FGFR2 anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Fibroblast Growth Factor Receptor 2 (FGFR2) Anticorps
  • FGFR2
  • FGFR2IIIb
  • bek
  • bfr-1
  • cd332
  • cek3
  • cfd1
  • ect1
  • fgfr-2
  • jws
  • k-sam
  • kgfr
  • tk14
  • tk25
  • xfgfr2
  • DKFZp469H1521
  • BBDS
  • BEK
  • BFR-1
  • CD332
  • CEK3
  • CFD1
  • ECT1
  • JWS
  • K-SAM
  • KGFR
  • TK14
  • TK25
  • AU043015
  • AW556123
  • Bek
  • Fgfr-2
  • Fgfr-7
  • Fgfr7
  • KGFRTr
  • svs
  • FGF-R
  • fgfr72IIIb
  • FGFR
  • fc56c05
  • wu:fc56c05
  • fibroblast growth factor receptor 2
  • fibroblast growth factor receptor 2 L homeolog
  • FGFR2
  • LOC100084641
  • fgfr2
  • Fgfr2
  • fgfr2.L
Épitope
N-Term
25
24
18
16
14
12
8
7
7
7
6
6
6
5
5
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
301
91
59
13
6
5
5
4
4
4
3
3
3
1
1
1
Hôte
Lapin
199
88
15
15
Clonalité
Polyclonal
Conjugué
Cet anticorp FGFR2 est non-conjugé
14
14
11
10
10
9
6
6
5
5
5
5
5
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
222
129
121
116
70
66
16
12
11
7
4
4
4
1
1
1
1
Fournisseur
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N° du produit (Fournisseur)
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N° du produit ABIN359854
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
12.3266735 ABIN1106281 IHC (p) WB Rabbit IgG C-Term Connectez-vous pour afficher Polyclonal 2
12.3266735 ABIN671751 FACS IHC (p) Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN391965 FACS IF IHC (p) WB Rabbit Ig Fraction AA 7-37, N-Term Connectez-vous pour afficher Polyclonal 9
1 ABIN1493068 IHC IHC (p) WB Rabbit C-Term Connectez-vous pour afficher Polyclonal 0
1 ABIN609608 IHC IHC (p) WB Rabbit IgG C-Term Connectez-vous pour afficher Polyclonal 0
1 ABIN671760 IHC (p) HRP Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN671753 IHC (p) Biotin Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN3030949 IHC (p) WB Rabbit IgG AA 805-820 Connectez-vous pour afficher Polyclonal 0
1 ABIN1690003 IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal 0

General

Antigène Fibroblast Growth Factor Receptor 2 (FGFR2) Anticorps
Épitope N-Term
(25), (24), (18), (16), (14), (12), (8), (7), (7), (7), (6), (6), (6), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(301), (91), (59), (13), (6), (5), (5), (4), (4), (4), (3), (3), (3), (1), (1), (1)
Hôte Lapin
(199), (88), (15), (15)
Clonalité
Polyclonal
Conjugué Cet anticorp FGFR2 est non-conjugé
(14), (14), (11), (10), (10), (9), (6), (6), (5), (5), (5), (5), (5), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(222), (129), (121), (116), (70), (66), (16), (12), (11), (7), (4), (4), (4), (1), (1), (1), (1)
Pubmed 5 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-FGFR2 anticorps

Détail du antigène FGFR2 Information d'application Stockage References for anti-FGFR2 antibody (ABIN359854) Images
Specificité This antibody reacts to FGFR2.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogène This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FGFR2.
Isotype Ig Fraction

Détail du antigène FGFR2

Détail du produit anti-FGFR2 anticorps Information d'application Stockage References for anti-FGFR2 antibody (ABIN359854) Images Haut de la page
Antigène
Autre désignation CD332 / FGFR-2 (FGFR2 Antibody Extrait)
Sujet FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in the gene are associated with many craniosynostotic syndromes and bone malformations. The genomic organization of the gene encompasses 20 exons. Alternative splicing in multiple exons, including those encoding the Ig-like domains, the transmembrane region and the carboxyl terminus, results in varied isoforms which differ in structure and specificity. Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF.Synonyms: BEK, FGFR2, Fibroblast growth factor receptor 2, KGFR, KSAM, Keratinocyte growth factor receptor 2
ID gène 2263, 9606
UniProt P21802
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding

Information d'application

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Stockage References for anti-FGFR2 antibody (ABIN359854) Images Haut de la page
Indications d'application ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Restrictions For Research Use only

Stockage

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Information d'application References for anti-FGFR2 antibody (ABIN359854) Images Haut de la page
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-FGFR2 antibody (ABIN359854)

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Information d'application Stockage Images Haut de la page
Background publications

Freeman, Gangula, Welm, Ozen, Foster, Rosen, Ittmann, Greenberg, Spencer et al.: "Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase ..." dans: Cancer research, Vol. 63, Issue 19, pp. 6237-43, 2003

Goriely, McVean, Röjmyr, Ingemarsson, Wilkie: "Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line." dans: Science (New York, N.Y.), Vol. 301, Issue 5633, pp. 643-6, 2003

Fomenkov, Huang, Topaloglu, Brechman, Osada, Fomenkova, Yuriditsky, Trink, Sidransky, Ratovitski: "P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome." dans: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23906-14, 2003

Katoh, Katoh: "Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26." dans: International journal of molecular medicine, Vol. 11, Issue 5, pp. 579-83, 2003

Katoh, Katoh: "FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26." dans: International journal of oncology, Vol. 22, Issue 5, pp. 1155-9, 2003

Images

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Information d'application Stockage References for anti-FGFR2 antibody (ABIN359854) Haut de la page
Images (Fournisseur)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (N-Term) antibody (ABIN359854) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (N-Term) antibody (ABIN359854) (LEFT) Western blot analysis of anti-hFGFR2-R22 Pab in 293 cell line lysates transien...