anti-Rat (Rattus) FGFR2 anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended FGFR2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Fibroblast Growth Factor Receptor 2 (FGFR2) Anticorps
  • FGFR2
  • FGFR2IIIb
  • bek
  • bfr-1
  • cd332
  • cek3
  • cfd1
  • ect1
  • fgfr-2
  • jws
  • k-sam
  • kgfr
  • tk14
  • tk25
  • xfgfr2
  • DKFZp469H1521
  • BBDS
  • BEK
  • BFR-1
  • CD332
  • CEK3
  • CFD1
  • ECT1
  • JWS
  • K-SAM
  • KGFR
  • TK14
  • TK25
  • AU043015
  • AW556123
  • Bek
  • Fgfr-2
  • Fgfr-7
  • Fgfr7
  • KGFRTr
  • svs
  • FGF-R
  • fgfr72IIIb
  • FGFR
  • fc56c05
  • wu:fc56c05
  • fibroblast growth factor receptor 2
  • fibroblast growth factor receptor 2 L homeolog
  • FGFR2
  • LOC100084641
  • fgfr2
  • Fgfr2
  • fgfr2.L
Épitope
AA 7-37, N-Term
23
23
19
16
13
12
7
7
7
6
6
5
5
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Singe, Souris, Rat (Rattus)
307
104
64
15
6
5
5
4
4
4
3
3
3
1
1
1
Hôte
Lapin
211
82
17
15
Clonalité
Polyclonal
Conjugué
Cet anticorp FGFR2 est non-conjugé
14
14
11
10
10
9
4
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
251
141
130
115
81
65
22
15
11
10
8
2
2
1
1
1
Options
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N° du produit ABIN391965
$ 335.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
14.117413 ABIN671751 FACS IHC (p) Rabbit IgG Connectez-vous pour afficher Polyclonal 0
12.755764 ABIN1690003 IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal 0
11.117413 ABIN359854 EIA IHC (p) WB Rabbit Ig Fraction N-Term Connectez-vous pour afficher Polyclonal 5
11.117413 ABIN1106281 IHC (p) WB Rabbit IgG C-Term Connectez-vous pour afficher Polyclonal 2
7 ABIN1493068 IHC IHC (p) WB Rabbit C-Term Connectez-vous pour afficher Polyclonal 0
4 ABIN5959557 ELISA IF IHC (p) WB Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN609608 IHC IHC (p) WB Rabbit IgG C-Term Connectez-vous pour afficher Polyclonal 0
1 ABIN671760 IHC (p) HRP Rabbit IgG Connectez-vous pour afficher Polyclonal 0
1 ABIN671753 IHC (p) Biotin Rabbit IgG Connectez-vous pour afficher Polyclonal 0

General

Antigène Fibroblast Growth Factor Receptor 2 (FGFR2) Anticorps
Épitope AA 7-37, N-Term
(23), (23), (19), (16), (13), (12), (7), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Singe, Souris, Rat (Rattus)
(307), (104), (64), (15), (6), (5), (5), (4), (4), (4), (3), (3), (3), (1), (1), (1)
Hôte Lapin
(211), (82), (17), (15)
Clonalité (Clone)
Polyclonal   ( )
Conjugué Cet anticorp FGFR2 est non-conjugé
(14), (14), (11), (10), (10), (9), (4), (4), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(251), (141), (130), (115), (81), (65), (22), (15), (11), (10), (8), (2), (2), (1), (1), (1)
Pubmed 10 références disponible
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Détail du produit anti-FGFR2 anticorps

Détail du antigène FGFR2 Information d'application Stockage References for anti-FGFR2 antibody (ABIN391965) Images
Specificité This FGFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~44 amino acids from the N-terminal region of human FGFR2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène This FGFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 AA from the N-terminal region of human FGFR2.
Clone RB01567
Isotype Ig Fraction
Plasmids, Primers & others

Détail du antigène FGFR2

Détail du produit anti-FGFR2 anticorps Information d'application Stockage References for anti-FGFR2 antibody (ABIN391965) Images Haut de la page
Antigène
Autre désignation FGFR2 (FGFR2 Antibody Extrait)
Sujet FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in the gene are associated with many craniosynostotic syndromes and bone malformations. The genomic organization of the gene encompasses 20 exons. Alternative splicing in multiple exons, including those encoding the Ig-like domains, the transmembrane region and the carboxyl terminus, results in varied isoforms which differ in structure and specificity. Isoform 1 has equal affinity for aFGF and bFGF but does not bind KGF.
Synonyms: fibroblast growth factor receptor 2
Poids moléculaire 92025 DA
ID gène 2263
UniProt P21802
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding

Information d'application

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Stockage References for anti-FGFR2 antibody (ABIN391965) Images Haut de la page
Indications d'application WB = 1:1000, IF = 1:50-100, FACS = 1:10-50, IHC (p) = 1:50-100
Restrictions For Research Use only

Stockage

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Information d'application References for anti-FGFR2 antibody (ABIN391965) Images Haut de la page
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C/-20 °C
Stockage commentaire Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption 6 months

References for anti-FGFR2 antibody (ABIN391965)

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Information d'application Stockage Images Haut de la page
Produit citée dans:

Guan, Gao, Zhou, Wang, Zheng, Guo, Chang, Li, Wang: "miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop." dans: Stem cells (Dayton, Ohio), Vol. 33, Issue 5, pp. 1589-600, 2015 Méthode utilisée: Western Blotting (WB)

Garcia, Shaffer, Alfaro, Smith, Sun, Zhao, Young, VanSaun, Eid: "Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2." dans: Oncogene, Vol. 31, Issue 18, pp. 2323-34, 2012 Méthode utilisée: Western Blotting (WB)

Matsui-Inohara, Uematsu, Narita, Satoh, Yonezawa, Kuroda, Ito, Yoneda, Kawarai, Sugiya, Watanabe, Senpuku: "E2F-1-deficient NOD/SCID mice developed showing decreased saliva production." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 234, Issue 12, pp. 1525-36, 2009 Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Page, Ambady, Holmes, Vilner, Kole, Kashpur, Huntress, Vojtic, Whitton, Dominko: "Induction of stem cell gene expression in adult human fibroblasts without transgenes." dans: Cloning and stem cells, Vol. 11, Issue 3, pp. 417-26, 2009 Méthode utilisée: Immunocytochemistry (ICC)

Mondrinos, Koutzaki, Lelkes, Finck: "A tissue-engineered model of fetal distal lung tissue." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 293, Issue 3, pp. L639-50, 2007 Méthode utilisée: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Background publications

Freeman, Gangula, Welm, Ozen, Foster, Rosen, Ittmann, Greenberg, Spencer et al.: "Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase ..." dans: Cancer research, Vol. 63, Issue 19, pp. 6237-43, 2003

Goriely, McVean, Röjmyr, Ingemarsson, Wilkie: "Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line." dans: Science (New York, N.Y.), Vol. 301, Issue 5633, pp. 643-6, 2003

Fomenkov, Huang, Topaloglu, Brechman, Osada, Fomenkova, Yuriditsky, Trink, Sidransky, Ratovitski: "P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome." dans: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23906-14, 2003

Katoh, Katoh: "Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26." dans: International journal of molecular medicine, Vol. 11, Issue 5, pp. 579-83, 2003

Katoh, Katoh: "FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26." dans: International journal of oncology, Vol. 22, Issue 5, pp. 1155-9, 2003

Images

Détail du produit anti-FGFR2 anticorps Détail du antigène FGFR2 Information d'application Stockage References for anti-FGFR2 antibody (ABIN391965) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) Western blot analysis of anti-hFGFR2-R22 Pab (ABIN391965) in 293 cell line lysates tr...
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
 image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) C:FGFR2/isolectinB4 (C) and FGFR1/isolectinB4 (D) staining of apparent mesenchymal ce...
Flow Cytometry (FACS) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) Overlay histogram showing Hela cells stained with ABIN2841761(green line). The cells ...
Immunofluorescence (IF) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0. 1% Triton X-100 permeabil...
Immunofluorescence (IF) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0. 1% Triton X-100 permeabil...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) Immunohistochemical analysis of paraffin-embedded H. liver section using FGFR2 Antibo...
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 7-37), (N-Term) antibody (ABIN391965) All lanes : Anti-FGFR2 Antibody (N-term) at 1:1000-1:2000 dilution Lane 1: DU145 whol...