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anti-Human CYP3A4 Anticorps:
anti-Rat (Rattus) CYP3A4 Anticorps:
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Human Polyclonal CYP3A4 Primary Antibody pour IHC (p), WB - ABIN514838
Yamashita, Honda, Nio, Nakamoto, Yamashita, Takamura, Tani, Zen, Kaneko: Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation. dans Cancer research 2010
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Human Monoclonal CYP3A4 Primary Antibody pour ICC, FACS - ABIN969512
van Waterschoot, Rooswinkel, Sparidans, van Herwaarden, Beijnen, Schinkel: Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. dans Drug metabolism and disposition: the biological fate of chemicals 2009
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Human Polyclonal CYP3A4 Primary Antibody pour Func, WB - ABIN2473177
Chirkov YuYu, Tyshchuk, Severina: Guanylate cyclase in human platelets with different aggregability. dans Experientia 1990
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Human Polyclonal CYP3A4 Primary Antibody pour IP, WB - ABIN947776
Fujiwara, Itoh: Extensive protein interactions involving cytochrome P450 3A4: a possible contributor to the formation of a metabolosome. dans Pharmacology research & perspectives 2014
Human Polyclonal CYP3A4 Primary Antibody pour WB - ABIN514839
De Bock, Colin, Boussery, Van Bocxlaer: Development and validation of an enzyme-linked immunosorbent assay for the quantification of cytochrome 3A4 in human liver microsomes. dans Talanta 2012
Cow (Bovine) Polyclonal CYP3A4 Primary Antibody pour WB - ABIN2784528
Werk, Lefeldt, Bruckmueller, Hemmrich-Stanisak, Franke, Roos, Küchle, Steubl, Schmaderer, Bräsen, Heemann, Cascorbi, Renders: Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. dans Clinical pharmacology and therapeutics 2014
Human Polyclonal CYP3A4 Primary Antibody pour ELISA - ABIN4302113
Choi, Skipper, Wishnok, Tannenbaum: Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450. dans Drug metabolism and disposition: the biological fate of chemicals 2005
It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (Montrer POR Anticorps) and cytochrome b(5 (Montrer CYB5A Anticorps)).
our findings suggest that CYP1A2 (Montrer CYP1A2 Anticorps), CYP3A4 and CYP3A5 (Montrer CYP3A5 Anticorps) play an important role in osteosarcoma tumorigenesis, at primary and metastatic sites, as well in treatment response
Our results provide information on CYP3A4 polymorphisms in Tibetan individuals which may help to optimize pharmacotherapy effectiveness by providing personalized medicine to this ethnic group.
Among two SNPs in CYP3A4 and CYP3A5 (Montrer CYP3A5 Anticorps) and 12 SNPs in ABCB1 (Montrer ABCB1 Anticorps) gene, an association with ovarian cancer risk was observed for ABCB1 (Montrer ABCB1 Anticorps) rs2157926 SNP only.
Low CYP3A4 Activity is associated with Crohn's Disease.
Cryopreserved human hepatocytes can be stored stably for more than a decade with little or no change in CYP3A4/5 induction.
Associations between SLCO1B1 (Montrer SLCO1B1 Anticorps) 521C and cholesterol response were not detected in African Americans (n = 333). Associations between CYP3A4*22 or CYP3A5 (Montrer CYP3A5 Anticorps)*3 and cholesterol response were not detected in whites or African Americans.
This kdeg value for CYP3A4 was in good agreement with recently reported values.
Sorafenib was poorly tolerated, and anti-Kaposi sarcoma (KS)activity was modest. Strong CYP3A4 inhibitors may contribute to sorafenib toxicity, and ritonavir has previously been shown to be a CYP3A4 inhibitor. Alternate antiretroviral agents without predicted interactions should be used when possible for concurrent administration with sorafenib
This study has identified 4 synonymous variants in the HCN4 (Montrer HCN4 Anticorps) gene and 3 SNPs in the CYP3A4 gene. None of the variants appear to have a major effect on the reduction of HR produced by ivabradine.
Findings show that at allelic and genotypic level polymorphisms in CYP3A4 and CYP1A2 (Montrer CYP1A2 Anticorps) are significantly associated with a reduced risk of drug addiction in Chinese individuals.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist\; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
cytochrome P450 3A4
, cytochrome P450, family 3, subfamily A, polypeptide 4
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4
, Cytochrome P450 CM3A-10
, cytochrome P450 3A21
, 1,8-cineole 2-exo-monooxygenase
, P450-III, steroid inducible
, albendazole monooxygenase
, albendazole sulfoxidase
, cytochrome P450 3A3
, cytochrome P450 HLp
, cytochrome P450 NF-25
, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3
, cytochrome P450-PCN1
, glucocorticoid-inducible P450
, nifedipine oxidase
, quinine 3-monooxygenase
, taurochenodeoxycholate 6-alpha-hydroxylase
, cytochrome P450 CYP3A12
, cytochrome P450 3A80