Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

WHSC2 Produits

(Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Catégories

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories WHSC2 en vedette

WHSC2 Anticorps

High quality antibodies with extensive validation data.

WHSC2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

WHSC2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (8)
N° du produit ABIN1724801
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (8)
N° du produit ABIN1724802
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IHC, FACS, IF/ICC
Validations
  • (7)
N° du produit ABIN1846367
Quantité 100 μL
Fiche technique Fiche technique

WHSC2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325326
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125741
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325325
Quantité 25 μg
Fiche technique Fiche technique

Dernières publications sur nos produits WHSC2

Kerzendorfer, Hannes, Colnaghi, Abramowicz, Carpenter, Vermeesch, ODriscoll: "Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome." dans: Human molecular genetics, Vol. 21, Issue 10, pp. 2181-93, (2012) (PubMed).

Yung, Narita, Komori, Yamaguchi, Handa: "Cellular dynamics of the negative transcription elongation factor NELF." dans: Experimental cell research, Vol. 315, Issue 10, pp. 1693-705, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à WHSC2

Negative elongation factor A (Nelf-A), negative elongation factor complex member A (Nelfa), negative elongation factor complex member A (nelfa), negative elongation factor complex member A L homeolog (nelfa.L), negative elongation factor complex member A (NELFA), negative elongation factor complex member A, Whsc2 (Nelfa), BcDNA:SD07139, CG5874, Dmel\\CG5874, fi75f03, MGC85474, NELF, NELF-A, nelf-a, nelfa, p/okcl.15, Whsc2, whsc2, WHSC2, Whsc2h, wu:fi75f03

Protein level used designations for WHSC2

  • CG5874-PA
  • CG5874-PB
  • NELF-A
  • Nelf-A-PA
  • Nelf-A-PB
  • negative elongation factor A
  • Wolf-Hirschhorn syndrome candidate 2 protein
  • Wolf-Hirschhorn syndrome candidate 2
  • negative elongation factor A-like
  • wolf-Hirschhorn syndrome candidate 2 protein
  • Wolf-Hirschhorn syndrome candidate 2 homolog
  • mWHSC2
Vous êtes ici:
Support technique