ADAM17 anticorps (Domain 17)
Aperçu rapide pour ADAM17 anticorps (Domain 17) (ABIN647517)
Antigène
Voir toutes ADAM17 AnticorpsReactivité
Hôte
Conjugué
Application
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Épitope
- Domain 17
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Specificité
- The ADAM17 goat antibody detects protein derived from human recombinant protein and HELA lysate at various concentrations.
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Réactivité croisée
- Souris, Rat (Rattus)
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Attributs du produit
- Goat Anti-ADAM17 / TACE, with HRP-conjugated secondary antibody
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Immunogène
- Peptide with sequence LQRQNRVDSKETEC, from the C Terminus of the protein sequence according to NP_003174.3. was used as immunogen.
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Isotype
- IgG
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anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibody
ADAM17 Reactivité: Humain WB, IHC Hôte: Souris Monoclonal C7 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-314) antibodyADAM17 Reactivité: Humain WB, ELISA, IHC (p), PLA Hôte: Souris Monoclonal 1F6 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) antibodyADAM17 Reactivité: Humain WB, FACS, IF (p) Hôte: Lapin Monoclonal 25GB395 unconjugated Recombinant Antibody
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 201-300) antibodyADAM17 Reactivité: Humain, Rat, Souris WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 226-473) antibodyADAM17 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibodyVerified ADAM17 Reactivité: Humain WB, ELISA Hôte: Chèvre Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) antibodyKO Validated ADAM17 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) antibodyADAM17 Reactivité: Humain, Rat, Souris WB, FACS, IF (cc) Hôte: Lapin Monoclonal 9E7 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (AA 215-315) antibodyADAM17 Reactivité: Humain WB, ELISA, IHC, IHC (p), PLA Hôte: Souris Monoclonal 1F6 unconjugated
anti-ADAM Metallopeptidase Domain 17 (ADAM17) (pThr735) antibodyADAM17 Reactivité: Humain, Rat, Souris WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
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Restrictions
- For Research Use only
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Reconstitution
- Supplied as 100 µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.
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Stock
- -20 °C
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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Autre désignation
- ADAM17 / TACE
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Sujet
- ADAM17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), CSVP, TACE, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM metallopeptidase domain 17, TNF-alpha converting enzyme, a disintegrin and metalloproteinase domain 17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), snake venom-like protease. Tumor necrosis factor beta (TNFbeta), also known as lymphotoxin, is a pleiotropic cytokine that has a molecular weight of 25 kDa. TNFalpha, also known as cachetin, is a 17 kDa cytokine that binds to the same receptors, producing an array of effects similar to those of TNFbeta. TNFbeta and TNFalpha share 30% amino acid homology and have similar biological activities. TNFbeta is produced by activated lymphocytes, including CD4+ T helper cell type 1 lymphocytes, CD8+ lymphocytes and certain B lymphoblastoid cell lines. TNFalpha is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFbeta and TNFalpha can modulate many immune and inflammatory functions while having the ability to inhibit tumor growth. TACE (for TNFalpha converting enzyme) is a metalloproteinase that cleaves the membrane-bound TNFalpha precursor to release soluble TNFalpha.
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NCBI Accession
- NP_003174
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Pathways
- Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
Antigène
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