p53 anticorps
Aperçu rapide pour p53 anticorps (ABIN781170)
Antigène
Voir toutes p53 (TP53) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Nucleus
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Purification
- Protein G-Sepharose affinity purified.
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Immunogène
- Recombinant fragment of Human TP53 (C-terminus).
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Isotype
- IgG
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Indications d'application
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000 .
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Autre désignation
- TP53
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Sujet
- This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.
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Poids moléculaire
- 50kDa
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NCBI Accession
- NM_000546
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Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
Antigène
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