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E-cadherin anticorps

L’anticorps anti-E-cadherin Polyclonal Lapin est utilisé pour la détection de E-cadherin dans des échantillons de Humain. Il a été validé pour WB, IF et IHC (p).
N° du produit ABIN265391
686,15 €
Plus frais de livraison 40,00 € et TVA
0.1 mg
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour E-cadherin anticorps (ABIN265391)

Antigène

Voir toutes E-cadherin (CDH1) Anticorps
E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Reactivité

  • 352
  • 125
  • 94
  • 18
  • 17
  • 16
  • 10
  • 9
  • 8
  • 8
  • 7
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Humain

Hôte

  • 240
  • 149
  • 8
  • 6
  • 4
  • 4
Lapin

Clonalité

  • 222
  • 177
  • 6
  • 4
Polyclonal

Conjugué

  • 213
  • 38
  • 29
  • 11
  • 9
  • 8
  • 7
  • 7
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp E-cadherin est non-conjugé

Application

  • 277
  • 185
  • 138
  • 102
  • 71
  • 62
  • 54
  • 51
  • 35
  • 27
  • 27
  • 21
  • 17
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Specificité

    This antibody detects endogenous levels of CD324 / Cadherin-1 protein (region surrounding Gly2).

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    Purification

    Affinity chromatography using epitope-specific immunogen.
  • Indications d'application

    ELISA: 1/40000approx. 1/60000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50-1/200. Immunofluorescence: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

    Autre désignation

    CD324 / Cadherin-1

    Sujet

    Cadherins comprise a family of Ca+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity, transmembrane domains and carboxyterminal intracellular domains. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as beta-Catenin, to regulate cadherin function. Members of this family of adhesion proteins include rat cadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P- cadherin and cadherin-5.Synonyms: CAM 120/80, CDH1, CDHE, E-cadherin, Epithelial cadherin, UVO, Uvomorulin

    Poids moléculaire

    approx. 98, 130 kDa

    ID gène

    999

    NCBI Accession

    NP_004351

    UniProt

    P12830

    Pathways

    Signalisation WNT, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
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