RIPK1 anticorps
Aperçu rapide pour RIPK1 anticorps (ABIN127073)
Antigène
Voir toutes RIPK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- The antibody detects 74 kDa RIP in Western blot analysis.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse and Rat.
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Purification
- Affinity Chromatography.
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Immunogène
- Synthetic peptide surrounding amino acid 645 of Human RIP
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anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 1-179) antibody
RIPK1 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 17-289) antibodyRIPK1 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 133-422) antibodyRIPK1 Reactivité: Humain WB, IHC, IHC (p) Hôte: Souris Monoclonal 2D6 unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 131-277) antibodyRIPK1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 3B5B6 unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) antibodyKD Validated RIPK1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 25GB2140 unconjugated Recombinant Antibody
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 385-650) antibodyRIPK1 Reactivité: Humain, Souris, Rat, Chien, Poulet WB, IHC, IP, IF Hôte: Souris Monoclonal 38-RIP unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 411-425), (Middle Region) antibodyRIPK1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 152-180), (N-Term) antibodyRIPK1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB34026 unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 328-458) antibodyRIPK1 Reactivité: Humain WB, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) (AA 1-656) antibodyRIPK1 Reactivité: Souris ELISA, IP Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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Western Blot: 2-6 μg/mL. Immunoprecipitation. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA as stabilizer and 0.01 % Thimerosal as preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C/-80 °C
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Stockage commentaire
- Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for long term storage.
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- RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
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Autre désignation
- RIP
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Sujet
- RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis factor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRADD, RAID, and TRAF2. RIP contains an N-terminal region with homology to protein kinase, an intermediate domain capable of association with MAPKKK and a C-terminal region containing an intracellular death domain motif. RIP activates both p38 MAP kinase and SAPK families. In vitro, RIP induces apoptosis, as well as SAPK/JNK and NF-kB activation. RIP possesses kinase activity as it autophosphorylates itself on serine and threonine residues.Synonyms: Cell death protein RIP, RIPK1, Receptor-Interacting Protein, Receptor-interacting serine/threonine-protein kinase 1, Serine/threonine-protein kinase RIP
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ID gène
- 8737
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NCBI Accession
- NP_003795
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UniProt
- Q13546
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Pathways
- Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway
Antigène
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