You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Anticorps

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (16) et ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Protéines (8) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
Comment commander chez anticorps-enligne
  • +33 (0)1 76 63 32 65
  • +33 (0)1 74 18 08 22
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 241 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Chien Lapin Inconjugué EIA, WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
357,50 €
Détails
Humain Lapin Inconjugué ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Connectez-vous pour afficher 5 to 7 Days
157,14 €
Détails
Chien Souris Inconjugué BP, ICC, IF, IHC, IHC (p), IP, Neut, WB Western Blot: MDR1/ABCB1 Antibody (C219) [ABIN153083] - Analysis of MDR1 in OSW canine lymphoma cell line using anti-MDR1 antibody. Image from verified customer review. Immunohistochemistry-Paraffin: MDR1/ABCB1 Antibody (C219) [ABIN153083] - Staining of formalin fixed paraffin embedded human liver tissue. 0.25 mL Connectez-vous pour afficher 3 to 5 Days
363,75 €
Détails
Humain Souris Inconjugué IHC (fro), IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 10 Days
374,00 €
Détails
Humain Souris Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
494,23 €
Détails
Humain Souris Inconjugué FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Connectez-vous pour afficher 8 to 10 Days
319,00 €
Détails
Humain Souris PE FACS   100 Tests Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué IHC, WB WB Suggested Anti-ABCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Lapin Inconjugué IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Connectez-vous pour afficher 8 to 11 Days
298,57 €
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails

ABCB1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , , , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , , ,
,
,
Mouse (Murine) , , ,
,
,

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps mieux référencés

  1. Dog (Canine) Monoclonal ABCB1 Primary Antibody pour BP, ICC - ABIN153083 : van Den Elsen, Kuntz, Hoedemaeker, Rose: Antibody C219 recognizes an alpha-helical epitope on P-glycoprotein. dans Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 11 references for ABIN153083

  2. Dog (Canine) Polyclonal ABCB1 Primary Antibody pour EIA, WB - ABIN401371 : Baker, Johnstone, Zalcberg, El-Osta: Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. dans Oncogene 2005 (PubMed)
    Show all 6 references for ABIN401371

  3. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN317070 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... dans Cancer research 1996 (PubMed)
    Show all 2 references for ABIN317070

  4. Human Polyclonal ABCB1 Primary Antibody pour IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. dans Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 references for ABIN4333368

  5. Human Monoclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. dans Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 references for ABIN1724927

  6. Human Monoclonal ABCB1 Primary Antibody pour IHC (fro), IF - ABIN1106124 : Callen, Baker, Simmers, Seshadri, Roninson: Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. dans Human genetics 1987 (PubMed)
    Show all 2 references for ABIN1106124

  7. Human Polyclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1043891 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. dans Journal of bioenergetics and biomembranes 2006 (PubMed)

  8. Human Monoclonal ABCB1 Primary Antibody pour FACS, IHC (fro) - ABIN317069 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

Plus d’anticorps contre ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 partenaires d’interaction

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (Montrer ABCB4 Anticorps), Bcrp (Montrer ABCG2 Anticorps) and Mrp1 (Montrer ABCC1 Anticorps) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Study investigated the effect of MDR1 (Montrer TBC1D9 Anticorps), CYP2D6 (Montrer CYP2D6 Anticorps) and CYP2C19 (Montrer CYP2C19 Anticorps) gene polymorphisms on prophylactic therapy response in migraine patients, suggested that migraine patients who receive topiramate prophylactic treatment should be assessed for the presence of the MDR1 (Montrer TBC1D9 Anticorps) C3435T polymorphism

  2. The GG and TT genotypes in CYP3A5 (Montrer CYP3A5 Anticorps)*3 and ABCB1 C3435T, respectively, were linked with higher TPC (Montrer CCDC6 Anticorps).

  3. The study revealed the correlation between ABCB1 DNA promoter methylation with rs1128503 and rs2032582 polymorphisms in malaria and was related to increased expression of ABCB1 protein levels in complicated malaria group when compared to uncomplicated malaria and control groups.

  4. findings suggest that Tetrandrine prevents paclitaxel-induced MDR by inhibiting Pgp (Montrer PGPEP1 Anticorps) overexpression through a mechanism that may involve the inhibition of NF-kappaB (Montrer NFKB1 Anticorps) signaling in osteosarcoma.

  5. Results find that ABCB1 is a target of miR (Montrer MLXIP Anticorps)-9 and reverses the effect of miR (Montrer MLXIP Anticorps)-9-mediated chemoresistance in K562 chronic myelogenous leukemia cells.

  6. findings suggest that osimertinib, a clinically-approved third-generation EGFR (Montrer EGFR Anticorps) TKI, can reverse ABCB1-mediated MDR, which supports the combination therapy with osimertinib and ABCB1 substrates may potentially be a novel therapeutic stategy in ABCB1-positive drug resistant cancers.

  7. Subcellular distribution of P-gp (Montrer ABCB4 Anticorps) and subsequent downregulation by pristimerin contribute to overcoming ABCB1-mediated chemotherapeutic drug resistance. Our findings suggested inducing the decrease of P-gp (Montrer ABCB4 Anticorps) membrane protein could be a new promising alternative therapeutic strategy in ABCB1-mediated Multidrug resistance.

  8. Rack1 (Montrer GNB2L1 Anticorps) regulated P-Glycoprotein activity, which was necessary for adriamycin-induced P-Glycoprotein - mediated phosphorylation of Anxa2 (Montrer ANXA2 Anticorps) and Erk1/2 (Montrer MAPK1/3 Anticorps).

  9. we found that the C3435T MDR1 (Montrer TBC1D9 Anticorps) polymorphism does not affect blood levels of cortisol or ACTH (Montrer POMC Anticorps) in healthy Japanese males. The effect size at alpha = 0.05 and at power 0.80 in the present sample size was 0.176 Thus, the present study suggests that the C3435T MDR1 (Montrer TBC1D9 Anticorps) polymorphism does not have a great impact on blood levels of cortisol or ACTH (Montrer POMC Anticorps).

  10. ABCB1 1236C/T variants might play a role in the risk of Parkinson's disease, whereas ABCB1 3435C/T polymorphisms might not contribute to susceptibility to disease (Meta-Analysis)

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Anticorps) activity and reverse the up-regulated P-gp (Montrer ABCB4 Anticorps) and MDR1 (Montrer ABCB4 Anticorps) levels induced by artemisinin.

  2. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Anticorps) gene expression and activity in an enantiomer-specific way.

  3. Pgp (Montrer ABCB4 Anticorps)-coupled ATPase (Montrer DNAH8 Anticorps) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  4. Data show that human transgenic mutant huntingtin (Montrer HTT Anticorps) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Anticorps)) which suggests that MDR1 (Montrer ABCB4 Anticorps) might be a potential therapeutic target for Huntington's disease.

  5. In vitro and in vivo downregulation of the ATP binding cassette transporter (Montrer ABCC3 Anticorps) B1 by the HMG-CoA reductase (Montrer HMGCR Anticorps) inhibitor simvastatin

  6. Efficient chemoprotection of CDD (Montrer CDA Anticorps) and MDR1 (Montrer ABCB4 Anticorps) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (Montrer FOXC1 Anticorps)-C and anthracycline application

  7. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (Montrer ABCB4 Anticorps) substrates.

  8. Data indicate that the brain penetration of ABT-888 in both Abcb1a (Montrer ABCB4 Anticorps)/1b-/- and Abcb1a (Montrer ABCB4 Anticorps)/1b-/-;Abcg2 (Montrer ABCG2 Anticorps)-/- mice was significantly higher than in wild-type mice.

  9. Expression of Abcb1 at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (Montrer NFE2L2 Anticorps).

  10. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) profil antigène

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • malic enzyme complex, mitochondrial (Mod2) anticorps
  • ABC20 anticorps
  • ABCB1 anticorps
  • Cd243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • Mdr anticorps
  • Mdr-1 anticorps
  • Mdr1 anticorps
  • Mdr1a anticorps
  • Mdr1b anticorps
  • Mod-2 anticorps
  • Mod-2r anticorps
  • Mod-2s anticorps
  • Mod2-r anticorps
  • Mod2-s anticorps
  • p-gp anticorps
  • PGP1 anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps
  • xemdr anticorps

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Anticorps
Avez-vous cherché autre chose?