anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Anticorps

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (17) et ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 244 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Connectez-vous pour afficher 5 to 7 Days
157,14 €
Détails
Humain Souris Inconjugué IHC (fro), IF, IHC (p), WB   0.1 mg Connectez-vous pour afficher 8 to 10 Days
374,00 €
Détails
Humain Lapin Inconjugué IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Connectez-vous pour afficher 8 to 11 Days
298,57 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-ABCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Humain Souris Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 6 to 8 Days
494,23 €
Détails
Humain Souris Inconjugué FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Connectez-vous pour afficher 8 to 10 Days
319,00 €
Détails
Chien Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
391,60 €
Détails
Humain Souris PE FACS   100 Tests Connectez-vous pour afficher 8 to 10 Days
517,00 €
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Hamster Souris Inconjugué IHC (fro), IF, IHC (p), WB 1 mL Connectez-vous pour afficher 8 to 10 Days
462,00 €
Détails

ABCB1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps mieux référencés

  1. Human Polyclonal ABCB1 Primary Antibody pour IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. dans Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 references for 4333368

  2. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN317070 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... dans Cancer research 1996 (PubMed)
    Show all 2 references for 317070

  3. Human Monoclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1724923 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. dans Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 references for 1724923

  4. Human Monoclonal ABCB1 Primary Antibody pour IHC (fro), IF - ABIN1106124 : Callen, Baker, Simmers, Seshadri, Roninson: Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. dans Human genetics 1987 (PubMed)
    Show all 2 references for 1106124

  5. Human Monoclonal ABCB1 Primary Antibody pour FACS, IHC (fro) - ABIN317069 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

  6. Human Polyclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1043891 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. dans Journal of bioenergetics and biomembranes 2006 (PubMed)

Plus d’anticorps contre ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 partenaires d’interaction

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (Montrer ABCB4 Anticorps), Bcrp (Montrer ABCG2 Anticorps) and Mrp1 (Montrer ABCC1 Anticorps) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. A subset of virus-specific CD161 (Montrer KLRB1 Anticorps)(+) T cells selectively express the multidrug transporter MDR1 (Montrer TBC1D9 Anticorps) and are resistant to chemotherapy in acute myeloid leukemia (Montrer BCL11A Anticorps).

  2. Primary CD4 (Montrer CD4 Anticorps)+P-gphigh T cells eliminate intracellular raltegravir more readily than P-gplow cells and HIV-1 viraemia correlates with P-gp (Montrer ABCB4 Anticorps) overall activity; specific CD4 (Montrer CD4 Anticorps)+P-gphigh T cell subsets could facilitate the persistence of viral replication in vivo and ultimately promote the appearance of drug resistance

  3. We observed an association between ABCB1 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (Montrer PPIG Anticorps) 3A4 *1B, 3A5*3 and ABCB1 C1236T.

  4. that residual SWI (Montrer SMARCA1 Anticorps)/SNF (Montrer SNRPA Anticorps) complexes lacking SMARCB1 (Montrer SMARCB1 Anticorps) are vital determinants of drug sensitivity, not just to TOP2A (Montrer TOP2A Anticorps)-targeted agents, but to the much broader range of cancer drugs effluxed by ABCB1.

  5. Patients with active rheumatoid arthritis have an increased function of ABCB1 and ABCG2 (Montrer ABCG2 Anticorps), and disease activity is the main determinant of this phenomena.

  6. the induction of P-gp (Montrer ABCB4 Anticorps) expression is causally associated with the expression of nestin (Montrer NES Anticorps) in leukemia cells

  7. High MDR1 (Montrer TBC1D9 Anticorps) expression is associated with Cisplatin Resistance in Gastric Cancer.

  8. overexpression is a key Initiator of resistance to tyrosine kinase (Montrer TXK Anticorps) inhibitors in chronic myeloid leukemia (Montrer BCL11A Anticorps) cell lines

  9. The results indicate that human BCRP (Montrer ABCG2 Anticorps) and not human P-gp (Montrer ABCB4 Anticorps) is involved in benzylpenicillin transport.

  10. Study suggests thatSNPs of 1236C > T contributed to an individual variation in anesthetic effects that follow the pediatric tonsillectomy, and also it was figured out that the patients with the MDR1 1236C > T CC genotype displayed superior anesthetic effects compared to those patients who possessed the CT + TT genotype

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (Montrer ABCB4 Anticorps) ATPase (Montrer DNAH8 Anticorps) activity

  2. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  3. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Anticorps) activity and reverse the up-regulated P-gp (Montrer ABCB4 Anticorps) and MDR1 (Montrer ABCB4 Anticorps) levels induced by artemisinin.

  4. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Anticorps) gene expression and activity in an enantiomer-specific way.

  5. Pgp (Montrer ABCB4 Anticorps)-coupled ATPase (Montrer DNAH8 Anticorps) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  6. Data show that human transgenic mutant huntingtin (Montrer HTT Anticorps) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Anticorps)) which suggests that MDR1 (Montrer ABCB4 Anticorps) might be a potential therapeutic target for Huntington's disease.

  7. In vitro and in vivo downregulation of the ATP binding cassette transporter (Montrer ABCC3 Anticorps) B1 by the HMG-CoA reductase (Montrer HMGCR Anticorps) inhibitor simvastatin

  8. Efficient chemoprotection of CDD (Montrer CDA Anticorps) and MDR1 (Montrer ABCB4 Anticorps) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (Montrer FOXC1 Anticorps)-C and anthracycline application

  9. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (Montrer ABCB4 Anticorps) substrates.

  10. Data indicate that the brain penetration of ABT-888 in both Abcb1a (Montrer ABCB4 Anticorps)/1b-/- and Abcb1a (Montrer ABCB4 Anticorps)/1b-/-;Abcg2 (Montrer ABCG2 Anticorps)-/- mice was significantly higher than in wild-type mice.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) profil antigène

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • malic enzyme complex, mitochondrial (Mod2) anticorps
  • ABC20 anticorps
  • ABCB1 anticorps
  • Cd243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • Mdr anticorps
  • Mdr-1 anticorps
  • Mdr1 anticorps
  • Mdr1a anticorps
  • Mdr1b anticorps
  • Mod-2 anticorps
  • Mod-2r anticorps
  • Mod-2s anticorps
  • Mod2-r anticorps
  • Mod2-s anticorps
  • p-gp anticorps
  • PGP1 anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps
  • xemdr anticorps

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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