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anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Anticorps

The protein encoded by RASA1 is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. De plus, nous expédions RASA1 Kits (14) et RASA1 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
RASA1 5921 P20936
RASA1 25676 P50904
RASA1 218397  
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Top anti-RASA1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 102 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB RASA1 Antibody (C-term) (ABIN656874) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the RASA1 antibody detected the RASA1 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of RASA1 / RasGAP (C-term) Cat.-No AP53583PU-N in 293 cell line lysates (35ug/lane). This demonstrates the RASA1 antibody detected the RASA1 protein (arrow). 0.4 mL Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Souris Inconjugué WB RASA1 monoclonal antibody (M01), clone 2C12 Western Blot analysis of RASA1 expression in IMR-32 on formalin-fixed paraffin-embedded human small Intestine (antibody concentration 6 µg/mL). 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Boeuf (Vache) Souris Inconjugué ICC, IF, IP, WB   0.05 mg Connectez-vous pour afficher 3 to 5 Days
363,75 €
Détails
Humain Lapin Inconjugué IHC (p), IP, WB 0.1 mg Connectez-vous pour afficher 8 to 10 Days
407,00 €
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 8 to 11 Days
340,48 €
Détails
Boeuf (Vache) Lapin Inconjugué IP, IHC, WB Western blot analysis of Ras GAP with lysates from Jutkat cells (Lane 1), mouse small intestine (Lane 2) and rat kidney (Lane 3). 100 μg Connectez-vous pour afficher 6 to 8 Days
337,56 €
Détails
Humain Souris Inconjugué IF, WB 100 μL Connectez-vous pour afficher 11 to 14 Days
583,17 €
Détails
Souris Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
653,02 €
Détails

RASA1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-RASA1 Anticorps mieux référencés

  1. Human Monoclonal RASA1 Primary Antibody pour WB - ABIN395417 : Hemerly, Bastos, Cerutti: Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas. dans European journal of endocrinology / European Federation of Endocrine Societies 2010 (PubMed)
    Show all 5 references for ABIN395417

  2. Human Polyclonal RASA1 Primary Antibody pour EIA, WB - ABIN954457 : Wiemels, Kang, Chang, Zheng, Kouyoumji, Zhang, Smith, Scelo, Metayer, Buffler, Wiencke: Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemia. dans Blood cells, molecules & diseases 2010 (PubMed)
    Show all 5 references for ABIN954457

  3. Human Polyclonal RASA1 Primary Antibody pour WB - ABIN656874 : Oinuma, Ito, Katoh, Negishi: Semaphorin 4D/Plexin-B1 stimulates PTEN activity through R-Ras GTPase-activating protein activity, inducing growth cone collapse in hippocampal neurons. dans The Journal of biological chemistry 2010 (PubMed)

  4. Cow (Bovine) Monoclonal RASA1 Primary Antibody pour ICC, IF - ABIN266005 : Muto, Yi, Harrison, Dávalos, Fancher, Ziegler, Feigel, Kondo, Nishibe, Sessa, Dardik: Eph-B4 prevents venous adaptive remodeling in the adult arterial environment. dans The Journal of experimental medicine 2011 (PubMed)

Plus d’anticorps contre RASA1 partenaires d’interaction

Human RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. Data show that patients with low level of Ras GTPase-activating protein 1 (RASA1) expression correlated with a significantly poorer survival compared to those with high level of RASA1 expression.

  2. Results show that oncogenic KRAS can activate Rho through miR-31-mediated regulation of RASA1 indicating miR-31 acts as a KRAS effector to modulate invasion and migration in pancreatic cancer.

  3. PTP1B (Montrer PTPN1 Anticorps) dephosphorylates PITX1 (Montrer PITX1 Anticorps) to weaken its protein stability and the transcriptional activity for p120RasGAP gene expression

  4. Data suggest that, in response to netrin-1 (Montrer NTN1 Anticorps)/netrin receptor (DCC (Montrer DCC Anticorps)) signaling, p120RasGAP is recruited to growth cones and supports axon outgrowth; p120RasGAP Src (Montrer SRC Anticorps) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  5. Maternal and fetal capillary malformation-arteriovenous malformation due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis have been found.

  6. This is the second largest study on isolated, non-syndromic Port-wine stain; data suggest that GNAQ (Montrer GNAQ Anticorps) is the main genetic determinant in this condition. Moreover, isolated port-wine stains are distinct from capillary malformations seen in RASA1 disorders.

  7. Data showed that hypoxia regulated the expression of miR (Montrer MLXIP Anticorps)-182 and RASA1 to promote HCC (Montrer FAM126A Anticorps) angiogenesis.

  8. p120RasGAP shields Akt (Montrer AKT1 Anticorps) from deactivating phosphatases in FGF1 (Montrer FGF1 Anticorps) signaling, but loses this ability once cleaved by caspase-3 (Montrer CASP3 Anticorps).

  9. Capillary malformation-arteriovenous malformation syndrome (CM-AVM) is an autosomal dominant disorder caused by RASA1 mutations.

  10. Multifocal, small, round-to-oval, pinkish-to-red cutaneous capillary malformations are seen in more than 90% of people with RASA1 mutations.

Cow (Bovine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. The data suggest that nitrosylation of H-Ras (Montrer HRAS Anticorps) rearranges the adsorptive potential and intrinsic GTPase (Montrer RACGAP1 Anticorps) activity of H-Ras (Montrer HRAS Anticorps) through modification of C-terminal cysteines of molecule.

Mouse (Murine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. Double-deficient RASA1-neurofibromin 1 (Montrer NF1 Anticorps) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (Montrer NOTCH1 Anticorps) gene.

  2. Rasa1 may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model

  3. Regulation of Rasa1 translation by miR (Montrer MLXIP Anticorps)-132 was seen in severed axons, demonstrating local function within the axon.

  4. RASA1 mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS subject and in the animal model.

  5. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 (Montrer D4S234E Anticorps) GTPase activating protein 1 (RASA1)

  6. 14-3-3 (Montrer YWHAQ Anticorps) negatively regulates the RGC downstream of the PI3-kinase (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps) signaling pathway

  7. Caspase-3 (Montrer CASP3 Anticorps) is a stress intensity sensor that controls cell fate by either initiating a RasGAP cleavage-dependent cell resistance program or a cell suicide response mediated by akt (Montrer AKT1 Anticorps).

  8. Data reveal a role for RASA1 as a physiological negative regulator of lymphatic endothelial cell growth that maintains the lymphatic vasculature in a quiescent functional state through its ability to inhibit Ras signal transduction.

  9. Ca2 (Montrer CA2 Anticorps)+-dependent monomer and dimer formation switches CAPRI (Montrer RASA4 Anticorps) Protein between Ras GTPase-activating protein (GAP) and RapGAP (Montrer RAP1GAP Anticorps) activities

  10. statins inhibit GGPP biosynthesis in the mevalonate pathway, and then inhibit signal transduction in the Ras/ERK (Montrer EPHB2 Anticorps) and Ras/Akt (Montrer AKT1 Anticorps) pathways, thereby inhibiting bFGF (Montrer FGF2 Anticorps), HGF (Montrer HGF Anticorps), TGF-beta (Montrer TGFB1 Anticorps) expression

RASA1 profil antigène

Profil protéine

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.

Gene names and symbols associated with RASA1

  • vacuolar peduncle (vap) anticorps
  • RAS p21 protein activator (GTPase activating protein) 1 (RASA1) anticorps
  • RAS p21 protein activator (GTPase activating protein) 1 (Rasa1) anticorps
  • RAS p21 protein activator 1 (Rasa1) anticorps
  • CG9209 anticorps
  • CM-AVM anticorps
  • CMAVM anticorps
  • D-RasGAP anticorps
  • Dmel\\CG9209 anticorps
  • Gap anticorps
  • GAPX anticorps
  • p120GAP anticorps
  • p120RASGAP anticorps
  • PKWS anticorps
  • RAS-GAP anticorps
  • Rasa anticorps
  • RASGAP anticorps

Protein level used designations for RASA1

CG9209-PA , CG9209-PB , CG9209-PC , CG9209-PD , Ras GTPase-activating protein , vacuolar peduncule , vacuolar pedunculi , vap-PA , vap-PB , vap-PC , vap-PD , ras GTPase-activating protein 1 , triphosphatase-activating protein , GAP , GTPase-activating protein , RAS p21 protein activator (GTPase activating protein RAS p21) , p120GAP , rasGAP , RAS p21 protein activator 1 , p120-rasGAP

GENE ID SPECIES
32569 Drosophila melanogaster
5921 Homo sapiens
282032 Bos taurus
25676 Rattus norvegicus
427327 Gallus gallus
479158 Canis lupus familiaris
100627579 Sus scrofa
218397 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-RASA1 (RASA1) Anticorps
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