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anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) Anticorps

The protein encoded by SMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. De plus, nous expédions SMAD, Mothers Against DPP Homolog 1 Kits (47) et SMAD, Mothers Against DPP Homolog 1 Protéines (22) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SMAD1 4086 Q15797
SMAD1 17125 P70340
SMAD1 25671  
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Top anti-SMAD, Mothers Against DPP Homolog 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 332 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Poulet Lapin Inconjugué WB WB Suggested Anti-SMAD1 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate WB Suggested Anti-SMAD1  Antibody Titration: 0.2-1 µg/mL  Positive Control: MCF7 cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
358,51 €
Détails
Bonobo Lapin Inconjugué EIA, WB 25 μL Connectez-vous pour afficher 8 to 10 Days
209,00 €
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB SMAD1 Antibody - N-terminal region (ARP38692_T100) validated by WB using Transfected 293T cell lysate at 2.41 µg/ul. 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Poulet Lapin Inconjugué WB WB Suggested Anti-SMAD1 Antibody Titration: 0.625ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-SMAD1  Antibody Titration: 0.625 µg/mL ELISA Titer: 1:1562500  Positive Control: Jurkat cell lysate 100 μL Connectez-vous pour afficher 6 to 8 Days
288,68 €
Détails
Bonobo Lapin Inconjugué EIA, WB 25 μL Connectez-vous pour afficher 8 to 10 Days
209,00 €
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from COLO cells, treated with EGF 200ng/ml 30', using Smad1 (Ab-465) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Smad1 (Ab-465) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué IF, ELISA, WB Western blot analysis of extracts from Jurkat/K562 cells, using Smad1 (Ab-187) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using Smad1 (Ab-187) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HeLa cells, using Smad1/5/9 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 6 to 8 Days
342,86 €
Détails
Humain Souris Inconjugué IF, WB Immunofluorescence of monoclonal antibody to SMAD1 on HeLa cell (antibody concentration 10 µg/mL). SMAD1 monoclonal antibody (M02), clone 1D3 Western Blot analysis of SMAD1 expression in IMR-32. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué WB SMAD1 Antibody (N-term) (ABIN1881815) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the SMAD1 antibody detected the SMAD1 protein (arrow). 400 μL Connectez-vous pour afficher 14 to 16 Days
335,24 €
Détails

SMAD1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-SMAD, Mothers Against DPP Homolog 1 Anticorps mieux référencés

  1. Human Monoclonal SMAD1 Primary Antibody pour IF, WB - ABIN393492 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. dans PLoS ONE 2010 (PubMed)
    Show all 5 references for ABIN393492

  2. Human Polyclonal SMAD1 Primary Antibody pour IF, WB - ABIN319351 : Li, Xin, Xu, Huang, Zhang, Chen, Zhang, Fu, Chang: CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription. dans Molecular and cellular biology 2003 (PubMed)
    Show all 3 references for ABIN319351

  3. Human Polyclonal SMAD1 Primary Antibody pour IHC, ELISA - ABIN1532214 : Liu, Hata, Baker, Doody, Cárcamo, Harland, Massagué: A human Mad protein acting as a BMP-regulated transcriptional activator. dans Nature 1996 (PubMed)
    Show all 2 references for ABIN1532214

  4. Chicken Polyclonal SMAD1 Primary Antibody pour WB - ABIN2779411 : Blount, Merlie: BIP associates with newly synthesized subunits of the mouse muscle nicotinic receptor. dans The Journal of cell biology 1991 (PubMed)
    Show all 2 references for ABIN2779411

  5. Human Polyclonal SMAD1 Primary Antibody pour ELISA, WB - ABIN1533926 : Hoodless, Haerry, Abdollah, Stapleton, OConnor, Attisano, Wrana: MADR1, a MAD-related protein that functions in BMP2 signaling pathways. dans Cell 1996 (PubMed)
    Show all 2 references for ABIN1533926

  6. Bonobo Polyclonal SMAD1 Primary Antibody pour EIA, WB - ABIN401466 : Sapkota, Alarcón, Spagnoli, Brivanlou, Massagué: Balancing BMP signaling through integrated inputs into the Smad1 linker. dans Molecular cell 2007 (PubMed)

  7. Cow (Bovine) Polyclonal SMAD1 Primary Antibody pour IHC, WB - ABIN2780719 : Jadlowiec, Zhang, Li, Campbell, Sfeir: Extracellular matrix-mediated signaling by dentin phosphophoryn involves activation of the Smad pathway independent of bone morphogenetic protein. dans The Journal of biological chemistry 2006 (PubMed)

Plus d’anticorps contre SMAD, Mothers Against DPP Homolog 1 partenaires d’interaction

Zebrafish SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. Data show that interplay of Smad1/5 and MAP kinase (Montrer MAPK1 Anticorps) signaling system (ERK (Montrer MAPK1 Anticorps) signalling) is essential for haemogenic endothelium-based haematopoietic stem cell emergence.

  2. this study uncovers that smad1 and smad9 (Montrer SMAD9 Anticorps) act redundantly to each other downstream of smad5 (Montrer SMAD5 Anticorps) to mediate ventral specification and to regulate embryonic myelopoiesis.

  3. that specificity of BMP signaling output, with respect to hematopoiesis, can be explained by differential functions of Smad1 and Smad5 (Montrer SMAD5 Anticorps).

Fruit Fly (Drosophila melanogaster) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. we identify key roles for the Zelda and Zerknullt transcription factors in establishing the resulting expression domain, and find widespread binding of insulator proteins to the Mad and Brinker-bound genomic regions. Analysis of embryos lacking the BEAF-32 insulator protein shows reduced transcription of a peak BMP target gene and a reduction in the number of amnioserosa cells, the fate specified by peak BMP signaling.

  2. Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues.

  3. During development, synaptic pMad accumulation followed the arrival and clustering of ionotropic glutamate (Montrer GRIN2A Anticorps) receptors at neuromuscular junction synapses.

  4. The actions of Brat at synapses are mediated through mothers against decapentaplegic (Mad), the signal transduction effector of the bone morphogenetic protein (BMP) signaling pathway.

  5. Mad has distinct signal transduction roles in the BMP (Montrer TGFb Anticorps) and Wnt (Montrer WNT4 Anticorps) pathways depending on its phosphorylation state.

  6. Yorkie (Montrer YAP1 Anticorps) and Mad physically bind each other, and 410 bp minimal enhancer of bantam that responds to Yorkie:Mad in vivo and in cultured cells, was identified.

  7. Heterodimers of SAX and TKV play an important role in extending the BMP activity gradient by facilitating DPP diffusion and assisting GBB signaling through functional complexes with type II receptors.

  8. importin (Montrer KPNA4 Anticorps)-beta11 function interacts with the bone morphogenic protein (Montrer TGFb Anticorps) pathway to regulate a pool of phosphorylated mothers against decapentaplegic that must be present at the presynapse for its proper development and function

  9. Mad depletion or overexpression produced Wingless-like embryonic segmentation phenotypes

  10. The downstream transcription factor Mothers against dpp is essential for the normal structural and functional development of the Drosophila neuromuscular junction, a synapse that displays activity-dependent plasticity.

Human SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. The expression of specific targets Smad1 (Montrer GARS Anticorps) and Osterix (Montrer SP7 Anticorps) was significantly increased in the presence of Pi and restored by coincubation with Mg(2 (Montrer MUC7 Anticorps)+). As miR (Montrer MLXIP Anticorps)-30b, miR (Montrer MLXIP Anticorps)-133a, and miR (Montrer MLXIP Anticorps)-143 are negatively regulated by Pi and restored by Mg(2 (Montrer MUC7 Anticorps)+) with a congruent modulation of their known targets Runx2 (Montrer RUNX2 Anticorps), Smad1 (Montrer GARS Anticorps), and Osterix (Montrer SP7 Anticorps), our results provide a potential mechanistic explanation of the observed upregulation of these master switches of o

  2. the BMP-2 (Montrer BMP2 Anticorps)/Smad1 (Montrer GARS Anticorps)/5/RUNX2 (Montrer RUNX2 Anticorps) signaling pathway participates in the silicon-mediated induction of COL-1 and osteocalcin (Montrer BGLAP Anticorps) synth

  3. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a is mediated by the increased expression of its target gene, SMAD1 (Montrer GARS Anticorps).

  4. The expression SMAD1 (Montrer GARS Anticorps) protein showed a significant correlation with lung cancer differentiation and lymphatic metastasis (P < 0.05), but not with genders, ages, tumor sizes and histological types of lung cancer patients (P>0.05).

  5. Overexpression of Smad1 (Montrer GARS Anticorps) is associated with prostate cancer.

  6. SMAD1 (Montrer GARS Anticorps) signaling may be a key pathway contributing the pathogenesis of Cardio-facio-cutaneous syndrome during early development.

  7. Smad1 (Montrer GARS Anticorps) elevation serves as a compensatory mechanism for p53 (Montrer TP53 Anticorps) deficiency by potentiating the activation of p53 (Montrer TP53 Anticorps) parallel pathways.

  8. Our data indicated that downregulation of miR (Montrer MLXIP Anticorps)-26b in osteosarcoma elevated the levels of CTGF (Montrer CTGF Anticorps) and Smad1 (Montrer GARS Anticorps), facilitating osteosarcoma metastasis

  9. Smad1 (Montrer GARS Anticorps) as a novel binding protein of KSHV latency-associated nuclear antigen (LANA). LANA interacted with and sustained BMP-activated p-Smad1 (Montrer GARS Anticorps) in the nucleus and enhanced its loading on the Id promoters.

  10. adult human Sertoli cells assumed similar morphological features, stable global gene expression profiles and numerous proteins, and activation of AKT (Montrer AKT1 Anticorps) and SMAD1 (Montrer GARS Anticorps)/5 during long-period culture.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. BetA can enhance in vivo osteogenic potentials of BMP2 (Montrer BMP2 Anticorps), possibly via stimulating Smad 1/5/8 and p38 (Montrer CRK Anticorps) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.

  2. Mutant GDF5 (Montrer GDF5 Anticorps) enhances ameloblast differentiation via accelerated BMP2 (Montrer BMP2 Anticorps)-induced Smad1-Smad5 (Montrer SMAD5 Anticorps)-Smad8 (Montrer SMAD9 Anticorps) phosphorylation.

  3. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a is mediated by the increased expression of its target gene, SMAD1.

  4. Data show that in R-Smad proteins Smad1;Smad5 (Montrer SMAD5 Anticorps) knockout embryonic stem cells (mESCs), the bone morphogenetic proteins (BMP)-SMAD signaling is dispensable for self-renewal.

  5. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  6. AHNAK (Montrer AHNAK Anticorps) plays a crucial role in body fat accumulation by regulating adipose tissue development via interaction with the SMAD1 protein and can be involved in metabolic homeostasis

  7. Results show that Smad1-deficient mice exhibit enhanced neuronal survival and improved neurological recovery at 7 days after transient middle cerebral artery occlusion suggesting that Smad1-mediated signal pathway is involved in stroke pathophysiology.

  8. The study reveals a novel miR (Montrer MLXIP Anticorps)-26a-GSK3beta (Montrer GSK3b Anticorps)-Smad1 signaling pathway in the regulation of mammalian axon regeneration.

  9. Nondiabetic Smad1-Tg had normal kidney however, diabetes resulted in mesangial expansion, consistent with an increase in glomerular phosphorylated Smad1. Heterozygous Smad1 KO mice exhibit attenuated mesangial expansion in the diabetic condition.

  10. The findings demonstrate for the first time that KMUP-1 can promote osteoblast maturation and differentiation in vitro via BMP-2 (Montrer BMP2 Anticorps)/Smad1/5/8 and Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathways.

Xenopus laevis SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. interactions between miR (Montrer MYLIP Anticorps)-26 and the Smad1 3'UTR (Montrer UTS2R Anticorps) modulate Smad1 function in the establishment of axial patterning.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. a detailed computational model for TGF-beta (Montrer TGFB1 Anticorps) signalling that incorporates elements of previous models together with crosstalking between Smad1/5/8 and Smad2 (Montrer SMAD2 Anticorps)/3 channels through a negative feedback loop dependent on Smad7 (Montrer SMAD7 Anticorps).

SMAD, Mothers Against DPP Homolog 1 (SMAD1) profil antigène

Profil protéine

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene names and symbols associated with SMAD1

  • SMAD family member 1 (smad1) anticorps
  • SMAD family member 1 (SMAD1) anticorps
  • MAD homolog 1 (Drosophila) (smad1) anticorps
  • Mothers against dpp (Mad) anticorps
  • SMAD family member 1 (Smad1) anticorps
  • SMAD family member 1 (smad1-a) anticorps
  • 2/23 anticorps
  • AI528653 anticorps
  • apg anticorps
  • BSP-1 anticorps
  • BSP1 anticorps
  • c28 anticorps
  • CG12399 anticorps
  • dMad anticorps
  • Dmel\\CG12399 anticorps
  • E(zen)2 anticorps
  • En(vvl) anticorps
  • fb39h09 anticorps
  • JV4-1 anticorps
  • JV41 anticorps
  • l(2)k00237 anticorps
  • mad anticorps
  • Madh1 anticorps
  • Madr1 anticorps
  • Mat anticorps
  • MLP anticorps
  • Mlp1 anticorps
  • MusMLP anticorps
  • p-Mad anticorps
  • pMad anticorps
  • pSmad anticorps
  • Smad anticorps
  • smad-1 anticorps
  • smad1 anticorps
  • wu:fb39h09 anticorps
  • wu:fb97e04 anticorps
  • xmad anticorps
  • Xmad1 anticorps
  • Xsmad1 anticorps

Protein level used designations for SMAD1

MAD homolog 1 , SMAD, mothers against DPP homolog 1 , mothers against decapentaplegic homolog 1 , mothers against decapentaplegic-like protein 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , SMA- and MAD-related protein 1 , SMAD 1 , SMAD family member 1 , mothers against DPP homolog 1 , CG12399-PA , CG12399-PB , Mad-PA , Mad-PB , apang , mother against decapentaplegic , mothers against decapentaplegi , mothers against decapentaplegic , mothers against dpp , phospho-Smad , phosphoSmad , phosphorylated smad , MAD, mothers against decapentaplegic homolog 1 , Mad-related protein 1 , TGF-beta signaling protein 1 , transforming growth factor-beta signaling protein 1 , transforming growth factor-beta-signaling protein 1 , Smad 1 , dwarfin-A , dwf-A , mMad1 , mad-related protein 1 , mothers-against-DPP-related 1 , MAD homolog1 (mothers against decapentaplegic, Drosophila) , mothers against DPP , BMP pathway effector , BMP signal transducer Smad1 , Sma- and Mad-related protein 1

GENE ID SPECIES
493211 Xenopus (Silurana) tropicalis
574340 Macaca mulatta
30628 Danio rerio
33529 Drosophila melanogaster
4086 Homo sapiens
17125 Mus musculus
25671 Rattus norvegicus
379664 Xenopus laevis
395680 Gallus gallus
475456 Canis lupus familiaris
397016 Sus scrofa
540488 Bos taurus
450142 Pan troglodytes
100432108 Pongo abelii
100033850 Equus caballus
443229 Ovis aries
100341544 Oryctolagus cuniculus
100727257 Cavia porcellus
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