anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) Anticorps

GABRG2 encodes a gamma-aminobutyric acid (GABA) receptor. De plus, nous expédions GABRG2 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GABRG2 29709 P18508
GABRG2 2566 P18507
GABRG2 14406 P22723
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Top anti-GABRG2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 117 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-GABRG2 Antibody Titration: </b>1.25ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Chèvre Inconjugué EIA, WB AP20117PU-N GABRG2 antibody staining of Mouse Brain lysate at 2 µg/ml (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué IHC, WB Western Blot: GABA-A R gamma 2 Antibody [ABIN152532] - Rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~46 kDa gamma2-subunit of GABA A Receptor. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$447.56
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Western Blot: GABA-A R gamma 2 Antibody [ABIN152497] - 10 ug of rat brain lysate showing immunolabeling of the ~45-47 kDa GABA - A R, g2-subunit. 0.05 mL Connectez-vous pour afficher 7 to 9 Days
$408.19
Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: GABRG2 Sample Type: Esophagus Tumor lysates Antibody Dilution: 1.0ug/ml Rabbit Anti-GABRG2 Antibody Catalog Number: ARP36738_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult Brain, cerebellum  Observed Staining: Cytoplasm in hepatocytes Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC (p), WB GABRG2 antibody (Center) (ABIN654148) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti GABRG2/GABA A Receptor gamma 2 Polyclonal Antibody, Unconjugated (ABIN754003) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: human colon carcinoma lysates Lane 2: mouse brain lysates probed with Anti GABRG2/GABA A Receptor gamma 2 Polyclonal Antibody, Unconjugated (ABIN754003) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 51kD. Observed band size: 51kD. 100 μL Connectez-vous pour afficher 3 to 7 Days
$295.90
Détails

GABRG2 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-GABRG2 Anticorps mieux référencés

  1. Human Polyclonal GABRG2 Primary Antibody pour IHC, WB - ABIN152532 : Joshi, Sun, Kapur: A mouse monoclonal antibody against the γ2 subunit of GABAA receptors. dans Hybridoma (2005) 2011 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal GABRG2 Primary Antibody pour ICC, IF - ABIN152497 : Borghese, Werner, Topf, Baron, Henderson, Boehm, Blednov, Saad, Dai, Pearce, Harris, Homanics, Harrison: An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice. dans The Journal of pharmacology and experimental therapeutics 2006 (PubMed)
    Show all 6 Pubmed References

  3. Rat (Rattus) Polyclonal GABRG2 Primary Antibody pour WB - ABIN361439 : Gomez, Froemke, Burden: Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. dans eLife 2014 (PubMed)
    Show all 9 Pubmed References

  4. Human Monoclonal GABRG2 Primary Antibody pour ICC, IP - ABIN2690511 : Kerti-Szigeti, Nusser: Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells. dans eLife 2016 (PubMed)

Plus d’anticorps contre GABRG2 partenaires d’interaction

Human gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) interaction partners

  1. This study identified a missense de novo mutation in the GABAA (Montrer GABRg1 Anticorps) receptor gamma2 subunit, P302L, in a patient with Dravet syndrome. The mutation has a novel pathogenic mechanism to cause defects in the conductance and gating of GABAA (Montrer GABRg1 Anticorps) receptors, which results in hyperexcitability and contributes to the pathogenesis of the genetic epilepsy Dravet syndrome.

  2. This study demonstrated that rescue of PTZ seizure threshold and thalamocortical oscillations in a Gabrg2+/Q390X KI mouse model of Dravet syndrome/GEFS+ by overexpression of wild-type gamma2HA subunits.

  3. Defects in GABRG2/GABAergic neurotransmission participate in the pathogenesis of genetic epilepsies including epileptic encephalopathies.

  4. This review suggest that the pathogenesis of GABRG2 mutations is likely to be due to a combination of reduction of channel function and disturbance of cellular homeostasis due to the presence of mutant protein.

  5. Nova1 (Montrer NOVA1 Anticorps) interacts with GABAARgamma2 not only in the central nervous system but also in hepatocellular carcinoma. Nova1 (Montrer NOVA1 Anticorps)'s potential mechanism as an oncogene (Montrer RAB1A Anticorps) may due to its interaction with GABAA (Montrer GABRg1 Anticorps) Rgamma2.

  6. Thus, the presence of active GABA-A receptors, associated with phenotype determination via Ca(2 (Montrer CA2 Anticorps)+)-signalling was demonstrated in differentiating human DA neurons.

  7. common variants of GABRG2, RELN (Montrer RELN Anticorps) and NRG3 (Montrer NRG3 Anticorps) and the GABRG2-RELN (Montrer RELN Anticorps)-PTCH1 (Montrer PTCH1 Anticorps) interaction networks might confer altered susceptibility to Hirschsprung disease.

  8. GABRG2, in combination with GABRA4 (Montrer GABRA4 Anticorps), is associated with autism spectrum disorder in an Argentine dataset.

  9. Deletion of the N-terminal extension and putative alpha-helix in heteromeric alpha1beta2gamma2 GABAA (Montrer GABRg1 Anticorps) receptors in the gamma2 subunits reduced the number of functional receptors and incorporation into mature receptors.

  10. Mutant GABRG2 may be responsible for genetic epilepsy as well neurodegeneration.

Mouse (Murine) gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) interaction partners

  1. GABAA (Montrer GABRg1 Anticorps) receptor (GABAAR) and the Na(+)-K(+)-2Cl(-) cotransporter (Montrer SLC12A1 Anticorps) (NKCC1 (Montrer SLC12A2 Anticorps)), but not the K(+)-Cl(-) cotransporter (Montrer SLC12A4 Anticorps) (KCC2 (Montrer SLC12A5 Anticorps)), were expressed in the terminals of the CRH (Montrer CRH Anticorps) neurons at the median eminence (ME). In contrast, CRH (Montrer CRH Anticorps) neuronal somata were enriched with KCC2 (Montrer SLC12A5 Anticorps) but not with NKCC1 (Montrer SLC12A2 Anticorps).

  2. This study demonstrated that the reduced local input to fast-spiking interneurons in the somatosensory cortex in the GABAA (Montrer GABRg1 Anticorps) gamma2 R43Q mouse model of absence epilepsy.

  3. Heterozygous Gabrg2(+/Q390X) KI mice are associated with a severe epileptic encephalopathy due to a dominant negative effect of the mutation, while heterozygous Gabrg2(+/-) KO mice are associated with mild absence epilepsy due to simple haploinsufficiency.

  4. This investigation demonstrates striking interfacial GABAA (Montrer GABRg1 Anticorps) receptor subunit selectivity in the native milieu, suggesting that asymmetric occupancy of heteropentameric ion channels by alkylphenol-based anesthetics is sufficient to induce modulation of activity.

  5. Study shows that the down-regulation of the gamma2 subunit of postsynaptic GABAARs in NG2 (Montrer Vcan Anticorps) cells that accompanies the postnatal switch from synaptic to extrasynaptic GABAergic transmission between interneurons and these cells in the barrel cortex

  6. Dendritic spine abnormalities of Gabrg2+/- mice suggest association of functional defects in glutamatergic transmission with the established anxious-depressive phenotype of these mice

  7. KIF21B (Montrer KIF21B Anticorps) participates in the delivery of GABAAR transport vesicles into dendrites.

  8. The study demonstrates the molecular and functional diversity of the GABAAR system within the mouse colon providing a framework for developing GABAAR-based therapeutics in GI disorders.

  9. these findings suggest that gephyrin (Montrer GPHN Anticorps) may be a key factor in BDNF (Montrer BDNF Anticorps)-dependent GABAAR regulation in the amygdala.

  10. This study showed that oscillatory activity in thalamic circuits is under the control of inhibition that involves gamma2 subunit-independent GABA-ARs (Montrer SLURP1 Anticorps)

GABRG2 profil antigène

Profil protéine

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with GABRG2

  • gamma-aminobutyric acid type A receptor gamma2 subunit (GABRG2) anticorps
  • gamma-aminobutyric acid (GABA) A receptor, gamma 2 (gabrg2) anticorps
  • gamma-aminobutyric acid type A receptor gamma 2 subunit (Gabrg2) anticorps
  • gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 (Gabrg2) anticorps
  • CAE2 anticorps
  • ECA2 anticorps
  • GABAA-R anticorps
  • Gabrg-2 anticorps
  • gabrg1 anticorps
  • gamma2 anticorps
  • GEFSP3 anticorps
  • si:ch211-145n14.1 anticorps

Protein level used designations for GABRG2

gamma-aminobutyric acid A receptor, gamma 1 , GABA(A) receptor subunit gamma-2 , gamma-aminobutyric acid receptor subunit gamma-2 , gamma-aminobutyric acid A receptor gamma 2 , gamma-aminobutyric acid (GABA) A receptor, gamma 2 , gamma-aminobutyric acid receptor subunit gamma-2-like , gamma-aminobutyric acid A receptor, gamma 2 , gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2 , gamma-aminobutyric acid A receptor, gamma 2 , GABA-A receptor gamma-2 subunit , GABA(A) receptor, gamma 2

GENE ID SPECIES
100059571 Equus caballus
779514 Xenopus (Silurana) tropicalis
100174267 Pongo abelii
100286791 Felis catus
100405062 Callithrix jacchus
29709 Rattus norvegicus
553402 Danio rerio
396289 Gallus gallus
2566 Homo sapiens
489141 Canis lupus familiaris
282240 Bos taurus
100516405 Sus scrofa
14406 Mus musculus
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