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Caspase 6 anticorps (active, C-Term)
CASP6
Reactivité: Humain, Souris, Rat
WB
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-Caspase 6 anticorps
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Antigène
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Caspase 6 (CASP6)
(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
Épitope
Tous les épitopes à travers Caspase 6 Anticorps.
active, C-Term
Reactivité
Toutes les réactivités sur Caspase 6 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur Caspase 6 Anticorps
Lapin
Clonalité
Toutes les clonalités sur Caspase 6 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers Caspase 6 Anticorps
Cet anticorp Caspase 6 est non-conjugé
Application
Tous les applications à travers Caspase 6 Anticorps.
Western Blotting (WB)
Specificité
The antibody detects the large subunit (18 kDa) of the active caspase-6. The antibody does not recognize other caspases.
Purification
Affinity purified
Immunogène
Synthetic peptide surrounding amino acids mapping to the Cterminus of the large fragment of human caspase-6.
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Information d'application
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Indications d'application
Western Blot: 0.5-4 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
Agent conservateur
Thimerosal (Merthiolate)
Précaution d'utilisation
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
-20 °C/-80 °C
Stockage commentaire
Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
Détails sur Caspase 6
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Antigène
Caspase 6 (CASP6)
(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
Autre désignation
Caspase-6 (CASP6 Produits )
Synonymes
anticorps xCaspase-6, anticorps mch2, anticorps caspase-6, anticorps zgc:112960, anticorps CASP6, anticorps casp6, anticorps Mch2, anticorps mCASP-6, anticorps MCH2, anticorps caspase 6 L homeolog, anticorps caspase 6, anticorps caspase 6, apoptosis-related cysteine peptidase, anticorps group XIIA secretory phospholipase A2, anticorps caspase-6, anticorps casp6.L, anticorps casp6, anticorps CASP6, anticorps CpipJ_CPIJ017008, anticorps Casp6
Sujet
Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Similar to other caspases, caspase-6 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Together with caspase-3, caspase-6 is one of the major caspases in apoptotic cells, and functions downstream of apoptosis inhibitors Bcl-2 and Bcl-xL. Caspase-6 has also been shown involving in the proteolysis of poly (ADP-ribose) polymerase (PARP) and nuclear lamin A.Synonyms: Apoptotic protease Mch-2, CASP-6, CASP6, MCH-2, MCH2
ID gène
839
NCBI Accession
NP_001217
UniProt
P55212
Pathways
Apoptose , Caspase Cascade in Apoptosis
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