Integrin beta 4 anticorps

N° du produit ABIN2688877

Détail du produit anti-Integrin beta 4 anticorps

Antigène: Integrin beta 4 (ITGB4)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 4 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM), Intracellular Staining (ICS)

Marque: BD Pharmingen™

Attributs du produit: Reacts with CD104, integrin β4 chain, a 205 kDa transmembrane glycoprotein, associated with CD49f (integrin α6 chain) to form the α6/β4 (CD49f/CD104) complex. CD104 is expressed on epithelial cells, Schwann cells, and some tumor cells. The CD49f/CD104 complex is located in the hemidesmosomes of the epidermis, suggesting its role in epidermal cell-basement membrane adhesion. The clone 450-11A recognizes the cytoplasmic domain of human CD104. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of intracellular A431 cells, an epidermal carcinoma cell line, analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD104 - Purified - Clone 450-11A - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: 450

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-Integrin beta 4 (ABIN2688877)

Jones, Kurpakus, Cooper, Quaranta: "A function for the integrin alpha 6 beta 4 in the hemidesmosome." dans: Cell regulation, Vol. 2, Issue 6, pp. 427-38, (1991) (PubMed).

Sonnenberg, Calafat, Janssen, Daams, van der Raaij-Helmer, Falcioni, Kennel, Aplin, Baker, Loizidou: "Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion." dans: The Journal of cell biology, Vol. 113, Issue 4, pp. 907-17, (1991) (PubMed).

Kennel, Epler, Lankford, Foote, Dickas, Canamucio, Cavalierie, Cosimelli, Venturo, Falcioni: "Second generation monoclonal antibodies to the human integrin alpha 6 beta 4." dans: Hybridoma, Vol. 9, Issue 3, pp. 243-55, (1990) (PubMed).

Tamura, Rozzo, Starr, Chambers, Reichardt, Cooper, Quaranta: "Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4." dans: The Journal of cell biology, Vol. 111, Issue 4, pp. 1593-604, (1990) (PubMed).

Hemler, Crouse, Sonnenberg: "Association of the VLA alpha 6 subunit with a novel protein. A possible alternative to the common VLA beta 1 subunit on certain cell lines." dans: The Journal of biological chemistry, Vol. 264, Issue 11, pp. 6529-35, (1989) (PubMed).

Détails sur Integrin beta 4

Antigène: Integrin beta 4 (ITGB4)

Autre désignation: CD104 (ITGB4 Produits)

Synonymes: anticorps AA407042, anticorps C230078O20, anticorps CD104, anticorps integrin subunit beta 4, anticorps integrin beta 4, anticorps ITGB4, anticorps Itgb4

Sujet: Synonyms: Integrin β4 chain

Pathways: Integrin Complex