FOXO1 anticorps (N-Term)

N° du produit ABIN2780391

Détail du produit anti-FOXO1 anticorps

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAEAPQVVEI DPDFEPLPRP RSCTWPLPRP EFSQSNSATS SPAPSGSAAA

Homologie: Cow: 92%, Dog: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 85%, Yeast: 85%

Attributs du produit: This is a rabbit polyclonal antibody against FOXO1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 655 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FOXO1 (ABIN2780391)

Hsu, Hu: "Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees." dans: Biogerontology, Vol. 15, Issue 4, pp. 389-400, (2014) (PubMed).

Détails sur FOXO1

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Autre désignation: FOXO1A (FOXO1 Produits)

Synonymes: anticorps FKH1, anticorps FKHR, anticorps FOXO1A, anticorps FoxO1a.1, anticorps foxo1, anticorps zgc:153388, anticorps Fkhr, anticorps Foxo1a, anticorps AI876417, anticorps Afxh, anticorps Fkhr1, anticorps fkh1, anticorps fkhr, anticorps foxo1a, anticorps xFoxO1, anticorps FoxO1A, anticorps foxo1a.2, anticorps forkhead box O1, anticorps forkhead box O1 a, anticorps forkhead box O1 L homeolog, anticorps forkhead box O1 b, anticorps FOXO1, anticorps foxo1a, anticorps Foxo1, anticorps foxo1, anticorps foxo1.L, anticorps foxo1b

Sujet: FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
Alias Symbols: FKH1, FKHR, FOXO1A
Protein Interaction Partner: EP300, AKT1, MST1, SIRT1, FHL2, ATG7, IRF3, FSHR, ESR1, Ubc, TXNRD1, RARA, MDM2, NLK, SKP2, SIRT2, STUB1, CREBBP, PML, LRPPRC, HOXA11, HNF4A, PARP1, DYRK1A, THRB, CSNK1G1, YWHAG, GSK3B, SMAD3, PAK1, PPARG, YWHAZ, SMAD4, AR, G6PC, SRC, CEBPB, FOXG1, HOXA10
Protein Size: 655

Poids moléculaire: 70 kDa

ID gène: 2308

NCBI Accession: NM_002015, NP_002006

UniProt: Q12778

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling