DOK1 anticorps (N-Term)
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- Antigène Voir toutes DOK1 Anticorps
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
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Épitope
- AA 9-39, N-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DOK1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B, M, Rat
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogène
- This DOK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human DOK1.
- Clone
- RB1759-RB1760
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DOK1 Anticorps primaire
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- Indications d'application
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
- Autre désignation
- DOK1 (DOK1 Produits)
- Synonymes
- anticorps P62DOK, anticorps Dok-1, anticorps AW557123, anticorps p62DOK, anticorps dok1, anticorps zgc:76914, anticorps docking protein 1, anticorps docking protein 1b, anticorps DOK1, anticorps Dok1, anticorps dok1b
- Sujet
- DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. DOK2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
- Poids moléculaire
- 52392
- ID gène
- 1796
- NCBI Accession
- NP_001184189, NP_001372
- UniProt
- Q99704
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