CD3 anticorps
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- Antigène Voir toutes CD3 Anticorps
- CD3
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Reactivité
- Humain
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Hôte
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Hamster
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD3 est non-conjugé
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Application
- Immunoprecipitation (IP), Western Blotting (WB)
- Specificité
- This antibody reacts with CD3 epsilon (23 kDa) on Western blotting.
- Purification
- Protein-A Agarose Chromatography of hybridoma supernatant.
- Immunogène
- Human T3 cells.
- Clone
- HAM25-1352
- Isotype
- IgG
- Top Product
- Discover our top product CD3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.2 containing 50 % Glycerol without preservatives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
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- Antigène
- CD3
- Autre désignation
- CD3 (CD3 Produits)
- Synonymes
- anticorps CD3, anticorps AI504783, anticorps CD3epsilon, anticorps T3e, anticorps cd3-gamma, anticorps cd3g, anticorps cd3g-a, anticorps cd3g/d, anticorps cd3gd, anticorps t3g, anticorps CD3e molecule, anticorps CD3d molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps CD3g molecule S homeolog, anticorps CD3E, anticorps CD3D, anticorps Cd3e, anticorps cd3g.S
- Sujet
- The antigen receptor of the T lymphocyte consists of two variable T-cell receptor chains (either TCR-apha, TCR-beta or TCR-gamma, TCR-delta) noncovalently linked to four different invariant membrane proteins ((CD3-γ , CD3-δ , CD3-ε , and the CD3-ζ homodimer). The CD3 genes are expressed early in thymocyte development, preceding the rearrangement and expression of the T-cell receptor genes. The CD3 epsilon polypeptide contributes to the cell surface display as well as to the signal transduction properties of the T-cell antigen receptor complex. Intriguingly, the distribution of CD3 epsilon is not restricted to T cells, since activated mouse, human, and avian natural killer (NK) cells do express intracytoplasmic CD3 epsilon polypeptides. CD3 epsilon is also present in the cytoplasm of fetal thymic T/NK bipotential progenitor cells, suggesting that it constitutes a component of the NK differentiation program.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
- ID gène
- 916
- NCBI Accession
- NP_000724
- UniProt
- P07766
- Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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