CD70 anticorps

N° du produit ABIN610194

Détail du produit anti-CD70 anticorps

Antigène: CD70 (CD70 Molecule (CD70))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD70 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)

Specificité: CD70 Molecule of approximately 30 kd.

Purification: Protein A purified

Immunogène: Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.

Clone: BU69

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, Flo, Func, ICC, IHC, IHC-Fr

Usage: Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate

Agent conservateur: Gentamicin sulfate

Précaution d'utilisation: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 4°C. Do not freeze.

Références pour anticorps anti-CD70 (ABIN610194)

Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).

Huan, van Adelsberg: "Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins." dans: The Journal of clinical investigation, Vol. 104, Issue 10, pp. 1459-68, (1999) (PubMed).

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70 (CD70 Produits)

Synonymes: anticorps CD27LG, anticorps Cd27l, anticorps Tnfsf7, anticorps CD27L, anticorps TNFSF7, anticorps CD70 antigen, anticorps CD70 molecule, anticorps Cd70 molecule, anticorps Cd70, anticorps CD70

Sujet: Name/Gene ID: CD70
Family: TNF

Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 Molecule, TNFSF7

ID gène: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints