NLRP6 anticorps (N-Term)

N° du produit ABIN783709

Détail du produit anti-NLRP6 anticorps

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP6 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects NLRP6 at N-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid peptide near the amino terminus of human NALP6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Détails sur NLRP6

Antigène: NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))

Autre désignation: NLRP6 (NLRP6 Produits)

Synonymes: anticorps NLRP6, anticorps NALP6, anticorps AVR, anticorps CLR11.4, anticorps NAVR, anticorps NAVR/AVR, anticorps PAN3, anticorps PYPAF5, anticorps AI504961, anticorps Avr, anticorps Nalp6, anticorps Navr, anticorps Navr/Avr, anticorps Pypaf5, anticorps NLR family pyrin domain containing 6, anticorps NLR family, pyrin domain containing 6, anticorps NLRP6, anticorps Nlrp6

Sujet: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.Synonyms: LRR and PYD domains-containing protein 6, NACHT, NALP6, PYPAF5

ID gène: 171389

NCBI Accession: NP_612202

UniProt: P59044

Pathways: Inflammasome