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NLRP6 anticorps (N-Term)
NLRP6
Reactivité: Humain
WB, EIA
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-NLRP6 anticorps
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Antigène
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NLRP6
(NLR Family, Pyrin Domain Containing 6 (NLRP6))
Épitope
Tous les épitopes à travers NLRP6 Anticorps.
N-Term
Reactivité
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Humain
Hôte
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Lapin
Clonalité
Toutes les clonalités sur NLRP6 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NLRP6 Anticorps
Cet anticorp NLRP6 est non-conjugé
Application
Tous les applications à travers NLRP6 Anticorps.
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificité
This antibody detects NLRP6 at N-term.
Réactivité croisée (Details)
Species reactivity (tested):Human
Purification
Affinity chromatography purified via peptide column
Immunogène
16 amino acid peptide near the amino terminus of human NALP6
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Buffer
PBS containing 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Détails sur NLRP6
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Antigène
NLRP6
(NLR Family, Pyrin Domain Containing 6 (NLRP6))
Autre désignation
NLRP6 (NLRP6 Produits )
Synonymes
anticorps NLRP6, anticorps NALP6, anticorps AVR, anticorps CLR11.4, anticorps NAVR, anticorps NAVR/AVR, anticorps PAN3, anticorps PYPAF5, anticorps AI504961, anticorps Avr, anticorps Nalp6, anticorps Navr, anticorps Navr/Avr, anticorps Pypaf5, anticorps NLR family pyrin domain containing 6, anticorps NLR family, pyrin domain containing 6, anticorps NLRP6, anticorps Nlrp6
Sujet
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.Synonyms: LRR and PYD domains-containing protein 6, NACHT, NALP6, PYPAF5
ID gène
171389
NCBI Accession
NP_612202
UniProt
P59044
Pathways
Inflammasome
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