CREB1 anticorps (CAMP Responsive Element Binding Protein 1)

Details for Product anti-CREB1 Antibody No. ABIN965928, Fournisseur: Connectez-vous pour afficher
Antigène
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein 1a
  • cyclic AMP response element binding protein
  • CREB1
  • creb1
  • Creb1
  • LOC100351999
  • creb1a
  • CREB
Reactivité
Humain, Souris, Singe, Rat (Rattus)
548
328
298
41
38
36
30
26
26
26
19
17
15
12
7
7
7
2
1
1
1
1
Hôte
Souris
450
100
11
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp CREB1 est non-conjugé
18
15
15
7
7
6
6
6
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
441
224
191
99
92
48
44
42
31
11
11
10
4
3
3
2
2
1
1
1
Options
Fournisseur
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Supplier Product No.
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Immunogène Purified recombinant fragment of human CREB1 expressed in E. Coli.
Clone 5G3
Isotype IgG1
Purification Ascitic fluid
Autre désignation CREB1 (CREB1 Antibody Extrait)
Sujet This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Synonyms: CREB, MGC9284, CREB1
Poids moléculaire 43kDa
ID gène 1385
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
Indications d'application Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Produit citée dans: Jansson, Ng, Fu, Depatie, Al Azzabi, Screaton: "Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 29, pp. 10161-6, 2008 (PubMed).

Seo, Chung: "CREB activates proteasomal degradation of DSCR1/RCAN1." dans: FEBS letters, Vol. 582, Issue 13, pp. 1889-93, 2008 (PubMed).

Background publications Mamdani, Alda, Grof, Young, Rouleau, Turecki: "Lithium response and genetic variation in the CREB family of genes." dans: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 4, pp. 500-4, 2008 (PubMed).

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