FBLN5
Reactivité: Humain
ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions
For Research Use only
Format
Liquid
Buffer
This antibody is stored in PBS, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." dans: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).
Nakamura, Ruiz-Lozano, Lindner, Yabe, Taniwaki, Furukawa, Kobuke, Tashiro, Lu, Andon, Schaub, Matsumori, Sasayama, Chien, Honjo: "DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries." dans: The Journal of biological chemistry, Vol. 274, Issue 32, pp. 22476-83, (1999) (PubMed).
FBLN5(Fibulin-5) promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling. FBLN5 (Fibulin-5) is expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes.