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anti-Mouse (Murine) Occludin Anticorps:
anti-Rat (Rattus) Occludin Anticorps:
anti-Human Occludin Anticorps:
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Human Polyclonal Occludin Primary Antibody pour IF (p), IHC (p) - ABIN687337
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. dans Neuroscience letters 2011
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Dog (Canine) Monoclonal Occludin Primary Antibody pour IF, WB - ABIN968360
Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues. dans The Journal of cell biology 1996
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Dog (Canine) Monoclonal Occludin Primary Antibody pour IF, WB - ABIN968361
Bolton, Anthony, Perry: Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo. dans Neuroscience 1998
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Dog (Canine) Monoclonal Occludin Primary Antibody pour IF, IHC (p) - ABIN337048
Krueger, Härtig, Reichenbach, Bechmann, Michalski: Blood-brain barrier breakdown after embolic stroke in rats occurs without ultrastructural evidence for disrupting tight junctions. dans PLoS ONE 2013
Human Polyclonal Occludin Primary Antibody pour IHC (fro), IF - ABIN2192203
Van Itallie, Anderson: Occludin confers adhesiveness when expressed in fibroblasts. dans Journal of cell science 1997
Cow (Bovine) Polyclonal Occludin Primary Antibody pour WB - ABIN2775620
Shen, Weber, Turner: The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady state. dans The Journal of cell biology 2008
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Human Polyclonal Occludin Primary Antibody pour ELISA, ICC - ABIN4341292
Liu, Xu, Ji, Liu, Mo, Tollerud, Gu, Zhang: Sublethal effects of zinc oxide nanoparticles on male reproductive cells. dans Toxicology in vitro : an international journal published in association with BIBRA 2016
Endothelial cellsTLR4 strongly regulates retinal vessel permeability by reducing expression of occludin and zonula occludens 1 (Montrer TJP1 Anticorps).
The zinc sensing receptor, ZnR/GPR39 (Montrer GPR39 Anticorps), triggers intracellular Ca(2 (Montrer CA2 Anticorps)+) signalling in colonocytes thereby inducing occludin expression. Moreover, ZnR/GPR39 (Montrer GPR39 Anticorps) is essential for epithelial barrier recovery in the dextran sodium sulfate (DSS (Montrer PMP22 Anticorps)) ulcerative colitis model.
Occludin expression by epidermal gammadelta T cells upon activation in response to epidermal stress allows them to move, which could be important for augmentation of immune responses via collaboration with other cells.
Intracellular zinc has an essential role in the maintenance of the intestinal epithelial tight junction barrier through regulation of occludin proteolysis and claudin-3 (Montrer CLDN3 Anticorps) transcription.
miR (Montrer MLXIP Anticorps)-429 could down-regulate the expression of Ocln by targeting the Ocln 3'-UTR (Montrer UTS2R Anticorps), which impaired intestinal barrier function in diabetes mellitus mice.
STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.
Tricellulin (Montrer MARVELD2 Anticorps) is a specific redox sensor and sealing element at 3-cell contacts and may compensate as a redox mediator for occludin loss at 2-cell contacts in vivo and in vitro.
These findings provide evidence for occludin playing a role in the invasion of Toxoplasma gondii in small intestinal epithelial cells.
occludin deficiency increases susceptibility to ethanol-induced colonic mucosal barrier dysfunction and liver damage in mice.
PHD3 (Montrer EGLN3 Anticorps) protects intestinal epithelial barrier function and reveal a hydroxylase-independent function of PHD3 (Montrer EGLN3 Anticorps) in stabilizing occludin
ZO-1 (Montrer TJP1 Anticorps) and occludin are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin at the blastocyst stage.
ADMA has potent adverse effects on cell proliferation, intracellular ROS (Montrer ROS1 Anticorps) generation, cell permeability, levels of ICAM-1 (Montrer ICAM1 Anticorps), and the tight-junction protein occludin
the presence of occludin at the membrane is dependent in part on calcium-sensitive signaling cascades
cyclic strain modulates both the expression and phosphorylation state of occludin and ZO-1 (Montrer TJP1 Anticorps) in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
These data demonstrate a novel mechanism of VEGF (Montrer VEGFA Anticorps)-induced occludin phosphorylation and ubiquitination that contributes to TJ trafficking and subsequent vascular permeability.
Glutamine (Montrer GFPT1 Anticorps) increased claudin-1 (Montrer CLDN7 Anticorps) expression in the colonic mucosa of patients with irritable bowel syndrome. In contrast, occludin expression was not significantly modified by glutamine (Montrer GFPT1 Anticorps).
Viral infectivity was significantly reduced by miR (Montrer MLXIP Anticorps)-200c but enhanced by miR (Montrer MLXIP Anticorps)-122.
The mechanism of transition from nondifferentiated to differentiated states in HepaRG cells was studed by proteomics. Two key factors (MMP-14 (Montrer MMP14 Anticorps) and OCLN) were validated by qRT-PCR and Western blot.
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (Montrer MLXIP Anticorps)-34c bound together to regulate the expressions of MAZ (Montrer MAZ Anticorps), ZO-1 (Montrer TJP1 Anticorps) and occludin.
Study provides evidence that occludin contributes to the regulation of size-reductive proliferation and epithelial cell maturation in a phosphorylation-dependent manner.
Report shows that silencing MARCH3 (Montrer MARCH3 Anticorps) protects the endothelial barrier and upregulates OCLN in MARCH3 (Montrer MARCH3 Anticorps)-depleted cells. MARCH3 (Montrer MARCH3 Anticorps) silencing results in the strengthening of cell-cell contacts and inactivates FoxO1 (Montrer FOXO1 Anticorps).
Downregulation of OCLN is associated with clear cell renal cell carcinoma (Montrer MOK Anticorps).
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
, tight-junction protein
, thiopurine methyltransferase
, tight junction protein occludin