anti-Poisson zèbre (Danio rerio) MAPKAP Kinase 2 anticorps pour Enzyme Immunoassay

Recommended MAPKAP Kinase 2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) Anticorps
  • mapkapk2
  • wu:fb30e10
  • wu:fc56c10
  • wu:fi03a01
  • MGC78852
  • MAPKAPK2
  • AA960234
  • MAPKAP-K2
  • MK-2
  • MK2
  • Rps6kc1
  • mitogen-activated protein kinase-activated protein kinase 2a
  • mitogen-activated protein kinase-activated protein kinase 2
  • MAP kinase-activated protein kinase 2
  • mapkapk2a
  • mapkapk2
  • MAPKAPK2
  • Mapkapk2
Épitope
AA 310-325
52
24
21
15
15
15
15
11
9
9
8
6
5
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Poulet, Hamster, Humain, Souris, Lapin, Rat (Rattus), Xenopus laevis, Poisson zèbre (Danio rerio)
223
171
136
44
14
8
7
5
5
5
4
3
3
2
1
1
Hôte
Lapin
195
25
24
Clonalité
Polyclonal
Conjugué
Cet anticorp MAPKAP Kinase 2 est non-conjugé
8
8
8
6
5
5
4
4
3
3
3
3
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
182
97
82
42
39
34
29
17
12
4
3
3
1
1
Fournisseur
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N° du produit ABIN5556688
391,60 €
Plus frais de livraison 40,00 € et TVA

anti-MAPKAP Kinase 2 Anticorps

Application / Reactivité Humain Souris Rat (Rattus) Poulet Hamster Lapin Xenopus laevis Poisson zèbre (Danio rerio)
Immunofluorescence (fixed cells) (IF/ICC) 2 Anticorps 2 Anticorps 1 Anticorps
Western Blotting (WB) 162 Anticorps 4 Anticorps 6 Anticorps 125 Anticorps 9 Anticorps 94 Anticorps 2 Anticorps 1 Anticorps
Proximity Ligation Assay (PLA) 1 Anticorps
Intracellular Staining (ICS) 4 Anticorps 4 Anticorps
Immunoprecipitation (IP) 29 Anticorps 1 Anticorps 4 Anticorps 18 Anticorps 2 Anticorps 12 Anticorps

General

Antigène Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) Anticorps
Épitope AA 310-325
(52), (24), (21), (15), (15), (15), (15), (11), (9), (9), (8), (6), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Poulet, Hamster, Humain, Souris, Lapin, Rat (Rattus), Xenopus laevis, Poisson zèbre (Danio rerio)
(223), (171), (136), (44), (14), (8), (7), (5), (5), (5), (4), (3), (3), (2), (1), (1)
Hôte Lapin
(195), (25), (24)
Clonalité
Polyclonal
Conjugué Cet anticorp MAPKAP Kinase 2 est non-conjugé
(8), (8), (8), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
(182), (97), (82), (42), (39), (34), (29), (17), (12), (4), (3), (3), (1), (1)
Fournisseur Connectez-vous pour afficher

Détail du produit anti-MAPKAP Kinase 2 anticorps

Détail du antigène MAPKAP Kinase 2 Information d'application Stockage Images
Séquence M-T-S-A-L-A-T-M-R-V-D-Y-E-Q-I-K
Attributs du produit Concentration: 0.9 mg/mL (by UV absorbance at 280 nm)
Purification Affinity Purified
Immunogène This antibody was affinity purified from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to aa 310-325 of rabbit MAPKAP Kinase 2 conjugated to KLH using maleimide. A terminal cysteine residue was added to facilitate coupling.

Détail du antigène MAPKAP Kinase 2

Détail du produit anti-MAPKAP Kinase 2 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation MAPKAP Kinase-2 (MAPKAPK2 Antibody Extrait)
Sujet MAPKAP kinase-2 (or MK2) is an acronym for mitogen-activated protein kinase-activated protein kinase-2. This enzyme is phosphorylated and activated by Erks and p38 MAPK in vitro. While multiple residues of MK2 are phosphorylated in vivo in response to stress, only four of the residues Thr25, Thr222, Ser272 and Thr334 are phosphorylated by p38 in an in vitro kinase assay. MK2 is serine-threonine protein kinase that contains a proline rich sequence and two putative SH3-binding sites. MK2 phosphorylates downstream components on a consensus Pro-X-Ser/Thr-Pro motif. The bestcharacterized MK2 substrate is hsp27. Although unknown, the physiological function of MK2 may be to increase stress resistance. MK2 is an essential component in the inflammatory response that regulates biosynthesis of TNF-α at a posttranscriptional level and MK2 is rapidly phosphorylated and activated in response to cytokines, stress and chemotactic factors.Synonyms: MAP kinase-activated protein kinase 2, MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAPK-2, MAPKAPK2, MK2
ID gène 9986
UniProt P49139
Domaine de recherche Inflammation, Kinases/Phosphatases, Signaling
Pathways Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades

Information d'application

Détail du produit anti-MAPKAP Kinase 2 anticorps Détail du antigène MAPKAP Kinase 2 Stockage Images Haut de la page
Indications d'application Suitable for use in Western blotting, ELISA, Immunoprecipitation and kinase assays. Although not tested, this antibody is likely functional in Immunohistochemistry and otherimmunological methods. Affinity purified anti-MAPKAP Kinase 2 is specific for MAPKAPKinase 2 and will not effectively immunoblot other isoforms of the kinase (i. e. MAPKAP K1or K3) from cell lines and/or tissues. Use a HeLa cell lysate as a positive control. MK2assays are often used and are easier and have less background than p38 kinase assays. Immunoprecipitation of MK2 using antibodies is used for this purpose. This product wasassayed by immunoblot and was found to be reactive to 20 g of crude protein extractprepared from HeLa cells. The gel was probed with Affinity Purified anti-MAPKAP Kinase2used at a dilution of 1: 2000. Use Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG(H&L) (GOAT) (Min X Bv Ch Gt GP Hs Hu Ms Rt & Sh Serum Proteins) as a secondary
Restrictions For Research Use only

Stockage

Détail du produit anti-MAPKAP Kinase 2 anticorps Détail du antigène MAPKAP Kinase 2 Information d'application Images Haut de la page
Concentration 0.9 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire Store undiluted at 2-8 °C. DO NOT FREEZE! This products is photosensitive and should be protected from light.