Aperçu des produits pour anti-ERBB3 (ERBB3) Anticorps

Full name:
anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Anticorps (ERBB3)
Chez www.anticorps-enligne.fr sont 535 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Anticorps de 32 de différents fournisseurs disponibles. De plus, nous expédions ERBB3 Protéines (43) et ERBB3 Kits (34) et beaucoup plus de produits pour cette protéine. Un total de 642 ERBB3 produits sont actuellement listés.
Synonymes:
c-erbB-3, c-erbB3, C76256, Erbb-3, ERBB3, erbB3-S, Erbb3r, Her3, LCCS2, MDA-BF-1, nuc-ErbB3, p45-sErbB3, p85-sErbB3, p180-ErbB3

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anti-ERBB3 Anticorps mieux référencés

  1. Human Polyclonal ERBB3 Primary Antibody pour FACS, IHC (p) - ABIN391949 : Katoh, Yazaki, Sugimura, Terada: c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. dans Biochemical and biophysical research communications 1993 (PubMed)
    Show all 7 references for 391949

  2. Human Monoclonal ERBB3 Primary Antibody pour FACS - ABIN4896267 : MacLeod, Elgadi, Bossi, Sankar, Pisio, Agopsowicz, Sharon, Graham, Hitt: HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice. dans Cancer gene therapy 2012 (PubMed)
    Show all 5 references for 4896267

  3. Human Monoclonal ERBB3 Primary Antibody pour ELISA (Capture), FACS - ABIN4899526 : Liu, Leng, Gunasekaran, Pentony, Shen, Howard, Stoops, Manchulenko, Razinkov, Liu, Fanslow, Hu, Sun, Hasegawa, Clark, Foltz, Yan: A Novel Antibody Engineering Strategy for Making Monovalent Bispecific Heterodimeric IgG Antibodies by Electrostatic Steering Mechanism. dans The Journal of biological chemistry 2015 (PubMed)
    Show all 5 references for 4899526

  4. Human Polyclonal ERBB3 Primary Antibody pour IF, IHC (p) - ABIN319383 : Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. dans Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
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  5. Human Monoclonal ERBB3 Primary Antibody pour IHC (p) - ABIN1687349 : Wang, Huang, Lyu, Cai, Yang, Li, Tan, Edgerton, Thor, Lee, Liu: Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. dans Breast cancer research : BCR 2014 (PubMed)
    Show all 2 references for 1687349

  6. Human Monoclonal ERBB3 Primary Antibody pour IHC (p) - ABIN1687359 : Huang, Wang, Lyu, Cai, Yang, Wang, Liu: The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells. dans Molecular cancer 2014 (PubMed)
    Show all 2 references for 1687359

  7. Human Monoclonal ERBB3 Primary Antibody pour FACS - ABIN4896259 : Sie, den Dunnen, Lourens, Meeuwsen-de Boer, Scherpen, Zomerman, Kampen, Hoving, de Bont: Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma. dans PLoS ONE 2015 (PubMed)

  8. Human Monoclonal ERBB3 Primary Antibody pour EIA, FACS - ABIN119014 : Rajkumar, Gullick: A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. dans British journal of cancer 1994 (PubMed)

  9. Human Polyclonal ERBB3 Primary Antibody pour ELISA, WB - ABIN185461 : van der Horst, Weber, Ullrich: Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma. dans International journal of cancer. Journal international du cancer 2004 (PubMed)

Plus d’anticorps contre ERBB3 partenaires d’interaction

Rhesus Monkey V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. Widespread expression of ErbB3 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization.

Pig (Porcine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. data confirmed that an ErbB3-driven pathway mediates a net positive influence in an in vivo model closely resembling human repair

Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. Simultaneous suppression of ErbB (Montrer EGFR Anticorps) kinases and androgen signaling by Celecoxib represents a novel strategy to interrupt the vicious cycle of AR/ErbB (Montrer EGFR Anticorps) cross-talk with the primary purpose of undermining their resilient signaling in prostate cancer progression.

  2. Targeting both HER2 (Montrer ERBB2 Anticorps) and HER3 resulted in an improved treatment effects on HER2 (Montrer ERBB2 Anticorps)-positive gastric cancer.

  3. HER3 is frequently overexpressed in high-grade dysplastic lesions of the gastroesophageal junction and may be a marker of invasive progression

  4. the mechanistic regulation and linkage of the ROR1 (Montrer ROR1 Anticorps)-HER3 and Hippo-YAP (Montrer YAP1 Anticorps) pathway in a cancer-specific context

  5. There were significant differences in human epidermal growth factor receptor (Montrer EGFR Anticorps) 2 and human epidermal growth factor receptor (Montrer EGFR Anticorps) 3 serum levels between the patients with tissue human epidermal growth factor receptor (Montrer EGFR Anticorps) 2-positive and tissue human epidermal growth factor receptor (Montrer EGFR Anticorps) 2-negative ( p = 0.0026, p = 0.000011) tumors, but not in the serum levels of human epidermal growth factor receptor (Montrer EGFR Anticorps) 4 ( p = 0.054).

  6. Results from circular dichroism spectroscopy, size exclusion chromatography with multiangle light scattering, dynamic light scattering, analytical ultracentrifugation, and small angle X-ray scattering each provide evidence that the EGFR (Montrer EGFR Anticorps) and HER3 C-terminal tails are intrinsically disordered with extended, non-globular structure in solution.

  7. YAP (Montrer YAP1 Anticorps) induces the expression of epidermal growth factor (EGF (Montrer EGF Anticorps)) receptors (EGFR (Montrer EGFR Anticorps), ERBB3) and production of EGF (Montrer EGF Anticorps)-like ligands (HBEGF (Montrer HBEGF Anticorps), NRG1 (Montrer NRG1 Anticorps) and NRG2 (Montrer NRG2 Anticorps)); YAP (Montrer YAP1 Anticorps) induces the expression of epidermal growth factor (EGF (Montrer EGF Anticorps)) receptors (EGFR (Montrer EGFR Anticorps), ERBB3) and production of EGF (Montrer EGF Anticorps)-like ligands (HBEGF (Montrer HBEGF Anticorps), NRG1 (Montrer NRG1 Anticorps) and NRG2 (Montrer NRG2 Anticorps))

  8. the phosphorylation levels of ErbB2 (Montrer ERBB2 Anticorps), ErbB3 and Akt (Montrer AKT1 Anticorps) and the protein levels of cyclin D1 (Montrer CCND1 Anticorps) were decreased by lapatinib treatment of HSC3, HSC4 and Ca9 (Montrer CA9 Anticorps)-22 cells

  9. In high-grade serous ovarian carcinoma (HGSC), high HER3 mRNA expression was a favorable prognostic factor for survival, while for high HER3 protein expression, a trend towards better survival was seen. A subgroup of HGSC with negative HER3 staining and negative HER3 mRNA levels showed most unfavorable survival.

  10. ERBB3 and ERBB4 (Montrer ERBB4 Anticorps) have roles in lung adenocarcinoma

Mouse (Murine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. Our results support a role for the hepatocellular ERBB (Montrer EGFR Anticorps) tyrosine kinases in fibrogenesis. Maximal impact to fibrogenesis occurred in the ERBB3 and EGFR (Montrer EGFR Anticorps)-ERBB3 DKO models, suggesting that EGFR (Montrer EGFR Anticorps)-ERBB3 heterodimeric signaling in damaged hepatocytes may play a more important role in liver fibrosis than EGFR-EGFR (Montrer EGFR Anticorps) homodimeric signaling.

  2. nuc-ErbB3 directly regulates levels of H3K27me3 in Schwann cells

  3. Data indicate that Sonic hedgehog (Shh (Montrer SHH Anticorps)) stimulate branching morphogenesis (BrM (Montrer SMARCA2 Anticorps)) and induced synthesis of mRNAs for Ptch1 (Montrer PTCH1 Anticorps) protein, epidermal growth factor (EGF (Montrer EGF Anticorps)) and receptors of the ErbB (Montrer EGFR Anticorps) receptors ErbB1 (Montrer EGFR Anticorps), ErbB2 (Montrer ERBB2 Anticorps) and ErbB3.

  4. ERBB3 is required for wound healing and for the progression of skin tumors in mice.

  5. The expression of ERBB3 in combination with ERBB4 (Montrer ERBB4 Anticorps) significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  6. Data indicate that increased expression of erbB3 plays a pivotal role in activating downstream PI-3K/Akt (Montrer AKT1 Anticorps) pathway and promoting erbB2 (Montrer ERBB2 Anticorps)-driven mammary/breast tumorigenesis.

  7. Suggest that ERBB3 may promote hepatocellular carcinoma through STAT3 (Montrer STAT3 Anticorps) activation.

  8. ERBB3 is crucial for the proliferation of Bergmann glia in the developing cerebellum.

  9. ErbB3 plays a key role in migration, as well as in myelination, in mouse Schwann lineage cells.

  10. Knock-down of Erbb3 with siRNA during early differentiation inhibits cardiomyogenesis in embryonic stem cells.

ERBB3 profil antigène

Antigen Summary

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) anticorps
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3) anticorps
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (Erbb3) anticorps
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3) anticorps
  • c-erbB-3 anticorps
  • c-erbB3 anticorps
  • C76256 anticorps
  • Erbb-3 anticorps
  • ERBB3 anticorps
  • erbB3-S anticorps
  • Erbb3r anticorps
  • Her3 anticorps
  • LCCS2 anticorps
  • MDA-BF-1 anticorps
  • nuc-ErbB3 anticorps
  • p45-sErbB3 anticorps
  • p85-sErbB3 anticorps
  • p180-ErbB3 anticorps

Protein level used designations for ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , avian erythroblastosis oncogene B 3 , c-erbB-3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , avian erythroblastosis oncogene B 3 receptor , glial growth factor receptor , receptor tyrosine kinase

GENE ID SPECIES
481105 Canis lupus familiaris
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
100468735 Ailuropoda melanoleuca
2065 Homo sapiens
29496 Rattus norvegicus
13867 Mus musculus
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