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Aperçu des produits pour anti-ERBB3 (ERBB3) Anticorps

Full name:
anti-V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Anticorps (ERBB3)
Chez sont 513 V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) Anticorps de 32 de différents fournisseurs disponibles. De plus, nous expédions ERBB3 Protéines (41) et ERBB3 Kits (31) et beaucoup plus de produits pour cette protéine. Un total de 614 ERBB3 produits sont actuellement listés.
c-erbB-3, c-erbB3, C76256, Erbb-3, ERBB3, erbB3-S, Erbb3r, Her3, LCCS2, MDA-BF-1, nuc-ErbB3, p45-sErbB3, p85-sErbB3, p180-ErbB3

Tous anti-ERBB3 Anticorps disponible

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anti-ERBB3 Anticorps mieux référencés

  1. Human Polyclonal ERBB3 Primary Antibody pour FACS, IHC (p) - ABIN391949 : Katoh, Yazaki, Sugimura, Terada: c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase. dans Biochemical and biophysical research communications 1993 (PubMed)
    Show all 7 references for ABIN391949

  2. Human Polyclonal ERBB3 Primary Antibody pour IP, WB - ABIN117962 : Liu, Carvajal, Carraway, Carraway, Pflugfelder: Expression of the receptor tyrosine kinases, epidermal growth factor receptor, ErbB2, and ErbB3, in human ocular surface epithelia. dans Cornea 2001 (PubMed)
    Show all 4 references for ABIN117962

  3. Human Polyclonal ERBB3 Primary Antibody pour IF, IHC (p) - ABIN319383 : Holbro, Beerli, Maurer, Koziczak, Barbas, Hynes: The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. dans Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 4 references for ABIN319383

  4. Human Monoclonal ERBB3 Primary Antibody pour IHC (p) - ABIN1687349 : Wang, Huang, Lyu, Cai, Yang, Li, Tan, Edgerton, Thor, Lee, Liu: Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer. dans Breast cancer research : BCR 2014 (PubMed)
    Show all 2 references for ABIN1687349

  5. Human Monoclonal ERBB3 Primary Antibody pour IHC (p) - ABIN1687359 : Huang, Wang, Lyu, Cai, Yang, Wang, Liu: The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells. dans Molecular cancer 2014 (PubMed)
    Show all 2 references for ABIN1687359

  6. Human Monoclonal ERBB3 Primary Antibody pour ICC, ELISA - ABIN969114 : Sakai, Yokote, Murakami-Murofushi, Tamura, Saijo, Nishio: Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway. dans Cancer science 2007 (PubMed)
    Show all 2 references for ABIN969114

  7. Human Monoclonal ERBB3 Primary Antibody pour EIA, FACS - ABIN119014 : Rajkumar, Gullick: A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines. dans British journal of cancer 1994 (PubMed)

  8. Cow (Bovine) Polyclonal ERBB3 Primary Antibody pour WB - ABIN782970 : van der Horst, Weber, Ullrich: Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma. dans International journal of cancer. Journal international du cancer 2004 (PubMed)

Plus d’anticorps contre ERBB3 partenaires d’interaction

Rhesus Monkey V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. Widespread expression of ErbB3 receptor mRNAs was found throughout the telencephalon of juvenile and adult monkeys with in situ hybridization.

Pig (Porcine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. data confirmed that an ErbB3-driven pathway mediates a net positive influence in an in vivo model closely resembling human repair

Human V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. the phosphorylation levels of ErbB2 (Montrer ERBB2 Anticorps), ErbB3 and Akt (Montrer AKT1 Anticorps) and the protein levels of cyclin D1 (Montrer CCND1 Anticorps) were decreased by lapatinib treatment of HSC3, HSC4 and Ca9 (Montrer CA9 Anticorps)-22 cells

  2. In high-grade serous ovarian carcinoma (HGSC), high HER3 mRNA expression was a favorable prognostic factor for survival, while for high HER3 protein expression, a trend towards better survival was seen. A subgroup of HGSC with negative HER3 staining and negative HER3 mRNA levels showed most unfavorable survival.

  3. ERBB3 and ERBB4 (Montrer ERBB4 Anticorps) have roles in lung adenocarcinoma

  4. Results suggest that silibinin is a potential anti-cancer drug to inhibit proliferative and invasive characteristics of the epithelial ovarian cancer (EOC) cells that exhibit an autocrine heregulin (HRG (Montrer NRG1 Anticorps))/HER3 protein (HRG (Montrer NRG1 Anticorps)/HER3) pathway.

  5. findings suggest that HBx promotes the progression of hepatocellular carcinoma by decreasing the stability of Nrdp1 (Montrer RNF41 Anticorps), which results in up-regulation of ErbB3

  6. High HER3 expression in colon cancer was associated to distal colon location and low-grade tumor.

  7. Correlate ERBB3 gene SNPs with rheumatoid arthritis susceptibility.

  8. Nrdp1S is a tumour suppressor that which potentiates the Nrdp1 (Montrer RNF41 Anticorps)-mediated ubiquitination and degradation of ErbB3. An Nrdp1S deficiency may also be an important factor in the loss of Nrdp1 (Montrer RNF41 Anticorps).

  9. In response to trastuzumab, both HER3 and the metalloprotease (Montrer ADAM8 Anticorps) ADAM10 (Montrer ADAM10 Anticorps) are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 ligand heregulin (Montrer NRG1 Anticorps) from the cell surface to activate HER3 and confer resistance to trastuzumab by inducing compensatory growth factor receptor (Montrer RYK Anticorps) signaling.

  10. the identification of HER3-V855A and its functional properties for the first time clearly implicates genomic HER3 activation in the pathogenesis of lung cancer.

Mouse (Murine) V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) (ERBB3) interaction partners

  1. nuc-ErbB3 directly regulates levels of H3K27me3 in Schwann cells

  2. Data indicate that Sonic hedgehog (Shh (Montrer SHH Anticorps)) stimulate branching morphogenesis (BrM (Montrer SMARCA2 Anticorps)) and induced synthesis of mRNAs for Ptch1 (Montrer PTCH1 Anticorps) protein, epidermal growth factor (EGF (Montrer EGF Anticorps)) and receptors of the ErbB (Montrer EGFR Anticorps) receptors ErbB1 (Montrer EGFR Anticorps), ErbB2 (Montrer ERBB2 Anticorps) and ErbB3.

  3. ERBB3 is required for wound healing and for the progression of skin tumors in mice.

  4. The expression of ERBB3 in combination with ERBB4 (Montrer ERBB4 Anticorps) significantly amplifies proliferation of lymphocytes upon ligand stimulation.

  5. Data indicate that increased expression of erbB3 plays a pivotal role in activating downstream PI-3K/Akt (Montrer AKT1 Anticorps) pathway and promoting erbB2 (Montrer ERBB2 Anticorps)-driven mammary/breast tumorigenesis.

  6. Suggest that ERBB3 may promote hepatocellular carcinoma through STAT3 (Montrer STAT3 Anticorps) activation.

  7. ERBB3 is crucial for the proliferation of Bergmann glia in the developing cerebellum.

  8. ErbB3 plays a key role in migration, as well as in myelination, in mouse Schwann lineage cells.

  9. Knock-down of Erbb3 with siRNA during early differentiation inhibits cardiomyogenesis in embryonic stem cells.

  10. Myocilin (Montrer MYOC Anticorps) binds to ErbB2 (Montrer ERBB2 Anticorps)/ErbB3, activates these receptors, and affects the downstream PI3K-AKT (Montrer AKT1 Anticorps) signaling pathway

ERBB3 profil antigène

Antigen Summary

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Alternative names and synonyms associated with ERBB3

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) anticorps
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (ERBB3) anticorps
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (Erbb3) anticorps
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Erbb3) anticorps
  • c-erbB-3 anticorps
  • c-erbB3 anticorps
  • C76256 anticorps
  • Erbb-3 anticorps
  • ERBB3 anticorps
  • erbB3-S anticorps
  • Erbb3r anticorps
  • Her3 anticorps
  • LCCS2 anticorps
  • MDA-BF-1 anticorps
  • nuc-ErbB3 anticorps
  • p45-sErbB3 anticorps
  • p85-sErbB3 anticorps
  • p180-ErbB3 anticorps

Protein level used designations for ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) , receptor tyrosine kinase ErbB3 , receptor tyrosine-protein kinase erbB-3-like , proto-oncogene-like protein c-ErbB-3 , receptor tyrosine-protein kinase erbB-3 , tyrosine kinase-type cell surface receptor HER3 , avian erythroblastosis oncogene B 3 , c-erbB-3 , c-erbB3 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 , avian erythroblastosis oncogene B 3 receptor , glial growth factor receptor , receptor tyrosine kinase

481105 Canis lupus familiaris
711407 Macaca mulatta
100008807 Oryctolagus cuniculus
100126862 Sus scrofa
100468735 Ailuropoda melanoleuca
2065 Homo sapiens
29496 Rattus norvegicus
13867 Mus musculus
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