ERBB3 anticorps (pTyr1328)

N° du produit ABIN7138931

Détail du produit anti-ERBB3 anticorps

Antigène: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Épitope: pTyr1328

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERBB3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 1328 (P-D-Y(p)-W-H) derived from Human Her3/ErbB3.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERBB3

Antigène: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Autre désignation: ERBB3 (ERBB3 Produits)

Synonymes: anticorps ErbB-3, anticorps HER3, anticorps LCCS2, anticorps MDA-BF-1, anticorps c-erbB-3, anticorps c-erbB3, anticorps erbB3-S, anticorps p180-ErbB3, anticorps p45-sErbB3, anticorps p85-sErbB3, anticorps ERBB3, anticorps C76256, anticorps Erbb-3, anticorps Erbb3r, anticorps Her3, anticorps nuc-ErbB3, anticorps erb-b2 receptor tyrosine kinase 3, anticorps v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), anticorps ERBB3, anticorps Erbb3

Sujet:

Background: Binds and is activated by neuregulins and NTAK.

Holbro, T. et al. (2003) Proc. Natl. Acad. Sci. USA 100, 8933-8938.
Kobayashi, M. et al. (2003) Oncogene 22, 1294-1301.
Kim, H.H. et al. (1994) J. Biol. Chem. 269, 24747-24755.
Yarden, Y. and Sliwkowski, M.X. (2001) Nature Rev. Mol. Cell. Biol. 2, 127-137.

Aliases: c erbB 3 antibody, c erbB3 antibody, Erb b2 receptor tyrosine kinase 3 antibody, ErbB 3 antibody, ERBB3 antibody, ERBB3 protein antibody, erbB3 S antibody, ERBB3_HUMAN antibody, Glial growth factor receptor antibody, HER 3 antibody, HER3 antibody, Human epidermal growth factor receptor 3 antibody, LCCS2 antibody, MDA BF 1 antibody, MGC88033 antibody, p180 ErbB3 antibody, p45 sErbB3 antibody, p85 sErbB3 antibody, proto-oncogene-like protein c ErbB 3 antibody, proto-oncogene-like protein c ErbB3 antibody, Proto-oncogene-like protein c-ErbB-3 antibody, Receptor tyrosine protein kinase erbB 3 antibody, Receptor tyrosine protein kinase erbB3 antibody, Receptor tyrosine-protein kinase erbB-3 antibody, Tyrosine kinase type cell surface receptor HER3 antibody, Tyrosine kinase-type cell surface receptor HER3 antibody, v erb b2 avian erythroblastic leukemia viral oncogene homolog 3 antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 antibody

UniProt: P21860

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway