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Aperçu des produits pour anti-TAB1 (TAB1) Anticorps

Full name:
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 Anticorps (TAB1)
Chez www.anticorps-enligne.fr sont 179 TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) Anticorps de 25 de différents fournisseurs disponibles. De plus, nous expédions TAB1 Protéines (7) et TAB1 Kits (3) et beaucoup plus de produits pour cette protéine. Un total de 199 TAB1 produits sont actuellement listés.
Synonymes:
3'-Tab1, 2310012M03Rik, b2b449Clo, Map3k7ip1

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anti-Human TAB1 Anticorps:

anti-Mouse (Murine) TAB1 Anticorps:

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anti-TAB1 Anticorps mieux référencés

  1. Human Monoclonal TAB1 Primary Antibody pour WB - ABIN393632 : McGovern, Jones, Taylor, Marciante, Yan, Dubinsky, Ippoliti, Vasiliauskas, Berel, Derkowski, Dutridge, Fleshner, Shih, Melmed, Mengesha, King, Pressman, Haritunians, Guo, Targan, Rotter: Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. dans Human molecular genetics 2010 (PubMed)
    Show all 5 references for ABIN393632

  2. Human Monoclonal TAB1 Primary Antibody pour IF, WB - ABIN393549 : Scholz, Sidler, Thali, Winssinger, Cheung, Neumann: Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN393549

  3. Human Polyclonal TAB1 Primary Antibody pour EIA, WB - ABIN401658 : Arch, Gedrich, Thompson: Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death. dans Genes & development 1998 (PubMed)
    Show all 2 references for ABIN401658

  4. Human Polyclonal TAB1 Primary Antibody pour EIA, WB - ABIN453175 : Yamaguchi, Nagai, Ninomiya-Tsuji, Nishita, Tamai, Irie, Ueno, Nishida, Shibuya, Matsumoto: XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. dans The EMBO journal 1999 (PubMed)
    Show all 2 references for ABIN453175

  5. Human Polyclonal TAB1 Primary Antibody pour IF, IHC (p) - ABIN303281 : Shibuya, Yamaguchi, Shirakabe, Tonegawa, Gotoh, Ueno, Irie, Nishida, Matsumoto: TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. dans Science (New York, N.Y.) 1996 (PubMed)

  6. Chicken Polyclonal TAB1 Primary Antibody pour WB - ABIN2785275 : Neil, Schiemann: Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression. dans Cancer research 2008 (PubMed)

Plus d’anticorps contre TAB1 partenaires d’interaction

Human TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) interaction partners

  1. TAK1 (Montrer MAP3K7 Anticorps)/TAB1 expression in non-small cell lung carcinoma tissue is significantly increased and closely associated with patient clinical prognosis.

  2. miR (Montrer MLXIP Anticorps)-29a repressed TAB1-mediated TIMP-1 (Montrer TIMP1 Anticorps) production in dermal fibroblasts, demonstrating that miR (Montrer MLXIP Anticorps)-29a may be a therapeutic target in SSc (Montrer CYP11A1 Anticorps).

  3. Data indicate that mitogen-activated protein kinase (Montrer MAPK1 Anticorps) (MAPK) p38 (Montrer MAPK1 Anticorps) activation is triggered by AMP (Montrer APRT Anticorps)-activated protein kinases (AMPK (Montrer PRKAA1 Anticorps)) and mediated by TAB1 protein.

  4. The amino acid sequence between positions 373 and 502 of TAB1 is required for TP interaction.

  5. USP18 (Montrer USP18 Anticorps) inhibits NF-kappaB (Montrer NFKB1 Anticorps) and NFAT (Montrer NFATC1 Anticorps) activation during Th17 differentiation by deubiquitinating the TAK1 (Montrer MAP3K7 Anticorps)-TAB1 complex.

  6. We found that endothelial TAK1 (Montrer MAP3K7 Anticorps) and TAB2 (Montrer TAB2 Anticorps), but not TAB1, were critically involved in vascular formation

  7. TAK1 (Montrer MAP3K7 Anticorps) plays a critical role in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation.

  8. data suggest a complex role of aa 452-457 of TAB1 in controlling p38 MAPK (Montrer MAPK14 Anticorps) activity and subcellular localization and implicate these residues in TAK1 (Montrer MAP3K7 Anticorps)- or p38 MAPK (Montrer MAPK14 Anticorps)-dependent post-transcriptional control of gene expression

  9. Phosphorylation and polyubiquitination of TAK1 (Montrer MAP3K7 Anticorps) are necessary for activation of NF-kappaB (Montrer NFKB1 Anticorps) by the Kaposi's sarcoma-associated herpesvirus vGPCR.

  10. Co-expression of TAK1 (Montrer MAP3K7 Anticorps) and TAB1 resulted in a functional and active TAK1 (Montrer MAP3K7 Anticorps)-TAB1 complex capable of directly activating full-length heterotrimeric mammalian AMP-activated protein kinase (AMPK (Montrer PRKAA2 Anticorps)) in vitro.

Mouse (Murine) TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 1 (TAB1) interaction partners

  1. We confirmed that PGC (Montrer PGC Anticorps)-1b inhibited downstream inflammatory signals via binding with TAB1 and thus preventing TAB1/TAK1 (Montrer NR2C2 Anticorps) binding and TAK1 (Montrer NR2C2 Anticorps) activation.

  2. The E3 ubiquitin ligase (Montrer MUL1 Anticorps) Itch inhibits p38alpha (Montrer MAPK14 Anticorps) signaling and skin inflammation through the ubiquitylation of Tab1.

  3. TAB1 and TAB2 (Montrer TAB2 Anticorps) are required for activated macrophages, making TAB1 and TAB2 (Montrer TAB2 Anticorps) effective targets to control inflammation by modulating macrophage survival.

  4. Both the MEKK1 (Montrer MAP2K1 Anticorps) PHD (Montrer PDC Anticorps) and TAB1 are critical for ES-cell differentiation

  5. The enhanced JNK (Montrer MAPK8 Anticorps) and IkappaB kinase (Montrer CHUK Anticorps) activation in DUSP14 (Montrer DUSP14 Anticorps)-deficient T cells was attenuated by TAB1 short hairpin RNA knockdown.

  6. TAB1 binding stabilizes active p38alpha (Montrer MAPK14 Anticorps) and induces rearrangements within the activation segment by helical extension of the Thr (Montrer TRH Anticorps)-Gly-Tyr (Montrer TYR Anticorps) motif, allowing autophosphorylation in cis (Montrer CISH Anticorps)

  7. We found that endothelial TAK1 (Montrer NR2C2 Anticorps) and TAB2 (Montrer TAB2 Anticorps), but not TAB1, were critically involved in vascular formation

  8. O-GlcNAcylation of TAB1 is required for full TAK1 (Montrer NR2C2 Anticorps) activation upon stimulation with IL-1 (Montrer IL1A Anticorps)/osmotic stress.

  9. Epithelial TAK1 (Montrer NR2C2 Anticorps) activity is regulated through two unique, TAB1-dependent basal & TAB2 (Montrer TAB2 Anticorps)-mediated stimuli-dependent mechanisms.

  10. XIAP (Montrer XIAP Anticorps)-TAB1-TAK1 (Montrer NR2C2 Anticorps) complex is dependent on NRAGE (Montrer MAGED1 Anticorps) for IKK-alpha (Montrer CHUK Anticorps)/beta phosphorylation and NF-kappaB (Montrer NFKB1 Anticorps) activation.

TAB1 profil antigène

Antigen Summary

The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with TAB1

  • TGF-beta activated kinase 1/MAP3K7 binding protein 1 (TAB1) anticorps
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Tab1) anticorps
  • 3'-Tab1 anticorps
  • 2310012M03Rik anticorps
  • b2b449Clo anticorps
  • Map3k7ip1 anticorps

Protein level used designations for TAB1

TAK1-binding protein 1 , TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 , mitogen-activated protein kinase kinase kinase 7-interacting protein 1 , transforming growth factor beta-activated kinase-binding protein 1 , TGF-beta-activated kinase 1-binding protein 1 , Tak1-binding protein 1 , beta activated kinase-1 binding protein-1 , mitogen activated protein kinase kinase kinase 7 interacting protein 1 , mitogen-activated protein kinase kinase kinase 7 interacting protein 1

GENE ID SPECIES
10454 Homo sapiens
66513 Mus musculus
315139 Rattus norvegicus
100358246 Oryctolagus cuniculus
418014 Gallus gallus
481245 Canis lupus familiaris
519958 Bos taurus
100153785 Sus scrofa
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