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Lymphoid Enhancer-Binding Factor 1 Kits ELISA (LEF1)
Chez www.anticorps-enligne.fr sont 3 Lymphoid Enhancer-Binding Factor 1 (LEF1) Kits ELISA de 2 de différents fournisseurs disponibles. De plus, nous expédions LEF1 Anticorps (129) et LEF1 Protéines (7) et beaucoup plus de produits pour cette protéine. Un total de 149 LEF1 produits sont actuellement listés.
3000002B05, AI451430, LEF-1, LEF1, TCF1ALPHA, TCF7L3, TCF10

LEF1 (LEF1) Kits ELISA par réactivité

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Zebrafish Lymphoid Enhancer-Binding Factor 1 (LEF1) interaction partners

  1. Amotl2a (Montrer AMOTL2 Kits ELISA) function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 (Montrer YAP1 Kits ELISA) and the Wnt (Montrer WNT2 Kits ELISA)/beta-catenin (Montrer CTNNB1 Kits ELISA) effector Lef1.

  2. Lef1 has a role in regulating Dusp6 (Montrer DUSP6 Kits ELISA) in formation of the zebrafish posterior lateral line primordium

  3. Nlk2 (Montrer NLK Kits ELISA) is essential for the phosphorylation and activation of Lef1 transcriptional activity in neural progenitor cells.

  4. Lef1 is required for progenitor cell identity in the zebrafish lateral line primordium.

  5. Lef1 sustains proliferation of leading zone progenitors, maintaining the primordium size and defining neuromast deposition rate.

  6. Data conclude that lef1-mediated Wnt (Montrer WNT2 Kits ELISA) signaling is involved in various aspects of primordium migration, although part of this implication is masked by a high level of developmental redundancy.

  7. Data show cooperation between Dnmt3 and an H3K9 methyltransferase G9a (Montrer EHMT2 Kits ELISA) in regulating lef1.

  8. high-affinity binding sites for Tcf (Montrer HNF4A Kits ELISA)/Lef1 within the boz promoter region

  9. Canonical Wnt (Montrer WNT2 Kits ELISA) signaling through Lef1 is required for hypothalamic neurogenesis.

  10. Domain-specific regulation of foxP2 (Montrer FOXP2 Kits ELISA) CNS expression by lef1.

Mouse (Murine) Lymphoid Enhancer-Binding Factor 1 (LEF1) interaction partners

  1. Uncovering a Pitx2 (Montrer PITX2 Kits ELISA)-Sox2 (Montrer SOX2 Kits ELISA)-Lef-1 transcriptional mechanism that regulates dental epithelial stem cells homeostasis and dental development.

  2. this study shows that the transcription factors Tcf1 (Montrer HNF1A Kits ELISA) and Lef1 suppress CD4 (Montrer CD4 Kits ELISA)+ T lineage genes in CD8 (Montrer CD8A Kits ELISA)+ T cells through intrinsic histone deacetylase (Montrer HDAC1 Kits ELISA) activity

  3. leukemic stem cells are therefore more sensitive to loss of Tcf1 (Montrer HNF1A Kits ELISA) and Lef1 than Hematopoietic Stem Cells in their self-renewal capacity.

  4. Sp5/8 bind directly to GC boxes in Wnt (Montrer WNT2 Kits ELISA) target gene enhancers and to adjacent, or distally positioned, chromatin-bound T-cell factor (Tcf) 1 (Montrer HNF1A Kits ELISA)/lymphoid enhancer factor (Lef) 1 to facilitate recruitment of beta-catenin (Montrer CTNNB1 Kits ELISA) to target gene enhancers.

  5. This paper demonstrates a cell-intrinsic requirement for transcription factors TCF1 (Montrer HNF1A Kits ELISA) and LEF1 for the development of all subsets of Natural Killer T cells.

  6. this study gives new insights into transcriptional regulating mechanisms of Wnt (Montrer WNT2 Kits ELISA)-mediated Isl1 (Montrer ISL1 Kits ELISA) expression during cardiomyocyte differentiation.

  7. data reveal LEF1 as a central regulator of iNKT cell number and Th2-type effector differentiation.

  8. These findings provide evidence for the existance of a posititve feedback loop connecting survivin expression in tumor cells to PI3K/Akt enhanced beta-catenin-Tcf/Lef-dependent transcription followed by secretion of VEGF and angiogenesis.

  9. TDG (Montrer TDG Kits ELISA), as a new coactivator, promotes beta-catenin (Montrer CTNNB1 Kits ELISA)/TCFs transactivation and functionally cooperates with CBP (Montrer CREBBP Kits ELISA) in canonical Wnt (Montrer WNT2 Kits ELISA) signaling.

  10. TCF-1 (Montrer HNF1A Kits ELISA) and LEF-1 adopted distinct genetic 'wiring' to promote the CD4 (Montrer CD4 Kits ELISA)(+) T cell fate and establish CD8 (Montrer CD8A Kits ELISA)(+) T cell identity.

Xenopus laevis Lymphoid Enhancer-Binding Factor 1 (LEF1) interaction partners

  1. Tcf (Montrer HNF4A Kits ELISA)/Lef genes encode factors of different activities, which function together in antagonistic or synergistic ways to modulate the intensity and outcome of Wnt (Montrer WNT2 Kits ELISA)/beta-catenin (Montrer CTNNB1 Kits ELISA) signalling and to trigger tissue-specific responses.

  2. Interaction of Xom and LEF1/TCF (Montrer HNF4A Kits ELISA)-factors is essential for ventral cell fate determination and LEF1/TCF (Montrer HNF4A Kits ELISA) factors may function as a point of convergence to mediate the combined signaling of Wnt (Montrer WNT2 Kits ELISA)/beta-catenin (Montrer CTNNB1 Kits ELISA) and BMP4 (Montrer BMP4 Kits ELISA)/Xom pathways during early embryogenesis.

Human Lymphoid Enhancer-Binding Factor 1 (LEF1) interaction partners

  1. Data indicate that microRNA miR (Montrer MLXIP Kits ELISA)-27a directly targets GSK-3beta (Montrer GSK3b Kits ELISA) and increases expression of beta-catenin (Montrer CTNNB1 Kits ELISA) and LEF1 in all-trans-retinoic acid (ATRA)-induced Hep2 cells.

  2. and CTU1/2, partner enzymes in U34 methoxycarbonylmethyl-2-thio (Montrer ACAA1 Kits ELISA) tRNA modification, are up-regulated in human breast cancers and sustain metastasis.

  3. EVI1 (Montrer MECOM Kits ELISA) transcription is directly regulated by LEF1/beta-catenin (Montrer CTNNB1 Kits ELISA) complex in myeloid blast crisis of chronic myeloid leukemia (Montrer BCL11A Kits ELISA). Loss of p53 (Montrer TP53 Kits ELISA) function as a key regulator for beta-catenin (Montrer CTNNB1 Kits ELISA)-EVI1 (Montrer MECOM Kits ELISA) in myeloid blast crisis of chronic myeloid leukemia (Montrer BCL11A Kits ELISA).

  4. LEF1 is a sensitive and specific marker for chronic lymphocytic B-cell leukemia

  5. a frequency of 4-9% expression of LEF1 bymantle cell lymphoma

  6. The results suggest a role for beta-catenin (Montrer CTNNB1 Kits ELISA)/LEF1-mediated transcription in both malignant transformation and metastasis of prostate cancer

  7. The results describe a novel mutation in LEF1 causing dysregulation of Wnt/B catenin signaling in eyelid sebaceous cancinoma

  8. LEF-1 and MITF (Montrer MITF Kits ELISA) regulate tyrosinase (Montrer TYR Kits ELISA) gene transcription in vitro via binding to its promoter.

  9. Methylprednisolone can suppress Wnt (Montrer WNT2 Kits ELISA) signaling pathway by down-regulating LEF-1 protein expression in chronic lymphocyte leukemia cells.

  10. Overexpression of LEF1 is a favorable prognostic factor in childhood ALL.

Pig (Porcine) Lymphoid Enhancer-Binding Factor 1 (LEF1) interaction partners

  1. The molecular characterisation of the porcine LEF1 gene and its association with number of teats and inverted teats in experimental and commercial populations, is described.

LEF1 profil antigène

Antigen Summary

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with LEF1

  • lymphoid enhancer-binding factor 1 (LEF1) Elisa Kit
  • lymphoid enhancer-binding factor 1 (LOC100352691) Elisa Kit
  • lymphoid enhancer-binding factor 1 (lef1) Elisa Kit
  • lymphocyte enhancer binding factor 1 (lef1) Elisa Kit
  • lymphoid enhancer binding factor 1 (Lef1) Elisa Kit
  • lymphoid enhancer factor XLEF-1B (lef1) Elisa Kit
  • 3000002B05 Elisa Kit
  • AI451430 Elisa Kit
  • LEF-1 Elisa Kit
  • LEF1 Elisa Kit
  • TCF1ALPHA Elisa Kit
  • TCF7L3 Elisa Kit
  • TCF10 Elisa Kit

Protein level used designations for LEF1

lymphoid enhancer binding factor-1 , lymphoid enhancer-binding factor 1 , lymphoid enhancer-binding factor 1-like , etID310027.1 , LEF-1 , lymphoid enhancer binding factor 1 short isoform , T cell-specific transcription factor 1-alpha , TCF1-alpha , lymphiod enhancer binding factor 1 , transcription factor LEF-1 , lymphoid enhancer binding factor 1

461425 Pan troglodytes
695776 Macaca mulatta
100011783 Monodelphis domestica
100352691 Oryctolagus cuniculus
100399759 Callithrix jacchus
100447785 Pongo abelii
100465982 Ailuropoda melanoleuca
100556215 Anolis carolinensis
100593051 Nomascus leucogenys
30701 Danio rerio
16842 Mus musculus
161452 Rattus norvegicus
779101 Xenopus laevis
51176 Homo sapiens
395865 Gallus gallus
478507 Canis lupus familiaris
100170126 Sus scrofa
535399 Bos taurus
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