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anti-Human CYP1A1 Anticorps:
anti-Rat (Rattus) CYP1A1 Anticorps:
anti-Mouse (Murine) CYP1A1 Anticorps:
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Human Monoclonal CYP1A1 Primary Antibody pour WB - ABIN1882232
Pande, Amos, Eng, Frazier: Interactions between cigarette smoking and selected polymorphisms in xenobiotic metabolizing enzymes in risk for colorectal cancer: A case-only analysis. dans Molecular carcinogenesis 2010
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Human Monoclonal CYP1A1 Primary Antibody pour WB - ABIN1882231
Sabitha, Reddy, Jamil: Smoking related risk involved in individuals carrying genetic variants of CYP1A1 gene in head and neck cancer. dans Cancer epidemiology 2010
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Human Polyclonal CYP1A1 Primary Antibody pour ICC, IF - ABIN446850
Bártíková, Boušová, Jedličková, Lněničková, Skálová, Szotáková: Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine. dans Molecules (Basel, Switzerland) 2014
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Human Polyclonal CYP1A1 Primary Antibody pour WB - ABIN947763
Kabátková, Zapletal, Tylichová, Ne?a, Machala, Milcová, Topinka, Kozubík, Vondrá?ek: Inhibition of ?-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation. dans Mutagenesis 2015
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Human Monoclonal CYP1A1 Primary Antibody pour IHC, ELISA - ABIN969511
Canova, Hashibe, Simonato, Nelis, Metspalu, Lagiou, Trichopoulos, Ahrens, Pigeot, Merletti, Richiardi, Talamini, Barzan, Macfarlane, Macfarlane, Holcátová, Bencko, Benhamou, Bouchardy, Kjaerheim et al.: Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. ... dans Cancer research 2009
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Human Polyclonal CYP1A1 Primary Antibody pour IHC (p), WB - ABIN392526
Foster, Jacobsen, Kenna, Schulz-Utermoehl, Morikawa, Salmu, Wilson: Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse. dans Toxicologic pathology 2012
Rat (Rattus) Polyclonal CYP1A1 Primary Antibody pour ELISA, WB - ABIN4302060
Sulem, Gudbjartsson, Geller, Prokopenko, Feenstra, Aben, Franke, den Heijer, Kovacs, Stumvoll, Mägi, Yanek, Becker, Boyd, Stacey, Walters, Jonasdottir, Thorleifsson, Holm, Gudjonsson, Rafnar et al.: Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. ... dans Human molecular genetics 2011
Human Polyclonal CYP1A1 Primary Antibody pour WB - ABIN4892771
Ikeda, Sasazuki, Natsukawa, Shaura, Koizumi, Kasuga, Ohnami, Sakamoto, Yoshida, Iwasaki, Tsugane: Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population. dans The American journal of gastroenterology 2008
Significant CYP1A1 expression increases over control animals was observed in ileum tissue in swine exposed to a single dose of 10 mgkg-bw-1 PAHs
There was no association between CYP1A1 C genotype and survival in the overall study population
The effect of human chorionic gonadotropin on the activities of cytochrome P-450 (Montrer CYP Anticorps) CYP1A1, cytochrome P-450 (Montrer CYP Anticorps) CYP2B1 (Montrer Cyp2b1 Anticorps) and methoxyresorufin O-demethylase (Montrer MBD2 Anticorps) (MROD) was studied in intact male pigs of 2 breeds.[CYP2B1 (Montrer Cyp2b1 Anticorps); MROD]
This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 and CYP1A2 (Montrer CYP1A2 Anticorps) in pigs.
The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A1 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.
Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P-450 (Montrer CYP Anticorps) CYP1A1 are reported.
Effect of beta-napthoflavone on AHR (Montrer AHR Anticorps)-related gene, CYP1A1, in the pig is reported.
AHR (Montrer AHR Anticorps), CYP1A1, CYP1A2 (Montrer CYP1A2 Anticorps), or CYP1B1 (Montrer CYP1B1 Anticorps) variants associated with head-and-neck squamous cell carcinoma risk in smokers.
Our meta-analysis revealed strong association of rs1048943 in CYP1A1, but a suggestive association of deletion polymorphisms in GSTT1 (Montrer GSTT1 Anticorps) and GSTM1 (Montrer GSTM1 Anticorps) with lung cancer, which provides a comprehensive insight on the overall effect of the polymorphic variants, reported in various case-control studies on Indian population, on the risk of lung cancer development
Increased expression of CYP1A1 is associated with ovarian/peritoneal endometriotic lesions.
mtDNA content, methylation of specific loci of mtDNA, and CYP1A1 methylation in placental tissue may serve as molecular signatures for the association between gestational tobacco smoke exposure and low birth weight.
Studied diosmetin effect on signal pathway and apoptosis in HepG2 cells. Dios-induced cell apoptosis could be reversed by p53 (Montrer TP53 Anticorps) blockade and the effects of Dios on cellular P53 (Montrer TP53 Anticorps) and CYP1A1/CYP1A2 proteins levels were examined. Found P53 (Montrer TP53 Anticorps), CYP1A1, and CYP1A2 (Montrer CYP1A2 Anticorps) proteins were up-regulated by diosmetin; p53 (Montrer TP53 Anticorps) downregulation by pifithrin caused inhibition of apoptosis.
Dependent on composition, mixtures of PAHs activate the AHR (Montrer AHR Anticorps) differently through varying transcription responses and expression of CYP1A1/COMT (Montrer COMT Anticorps) target genes in granulosa non-tumor and granulosa tumor cell lines.
the CYP1A1 polymorphisms are potential risk factors for digestive tract cancer.
was observed that the variant genotypes of GSTM1 (Montrer GSTM1 Anticorps), GSTT1 (Montrer GSTT1 Anticorps), GSTP1 (Montrer GSTP1 Anticorps) and CYP1A1 did not significantly increase the risk of cervical cancer (CC), however, statistically significant increased risk was observed for women who used wood for cooking and had GSTM1 (Montrer GSTM1 Anticorps) (null) genotype.
CYP1A1*2A was not associated with Colorectal Cancer(CRC (Montrer CALR Anticorps))development (OR = 1.566; 95% confidence interval [CI] = 0.90-2.73; p = 0.12); C allele-carrying individuals who had smoked within the past 5 years had a significant risk of CRC (Montrer CALR Anticorps) (OR = 2.28; 95% CI = 1.07-4.86; p = 0.043).
CYP1A1 polymorphisms were not associated with sporadic colorectal neoplasms.
Miroestrol suppressed beta-naphthoflavone increases in CYP1A1.
Taken together, CAPE decreases 3-MC-mediated CYP1A1 expression, and this inhibitory response is associated with inhibition of AhR (Montrer AHR Anticorps) and HIF-1alpha (Montrer HIF1A Anticorps) induction.
Our results support the hypothesis that CYP1A1 protects against hyperoxic lung injury by decreasing oxidative stress.
CYP1A1 contributes to nitric oxide bioavailability and blood pressure regulation mediated by dietary omega-3 polyunsaturated fatty acids.
Aryl hydrocarbon receptor (Montrer AHR Anticorps) mediated induction of hepatic CYP1A1/1A2 is dependent on the presence of ctnnb1 (Montrer CTNNB1 Anticorps).
Suggest that CYP1A induction by coplanar polychlorinated/brominated biphenyls depends on AhR (Montrer AHR Anticorps) transcriptional activity and not on AhR (Montrer AHR Anticorps) expression.
Identify hepatic proteins necessary for the AHR (Montrer AHR Anticorps)-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
In livers of HRN mice Cyp1a1, cytochrome b5 (Montrer CYB5A Anticorps) and mEH (Montrer EPHX1 Anticorps) can effectively activate BaP (Montrer PHB2 Anticorps) to DNA binding species, even in the presence of very low amounts of P450 (Montrer POR Anticorps) oxidoreductase (Montrer HSD17B6 Anticorps).
Reactive oxygen species production contributes to benzo[a]pyrene (BaP (Montrer PHB2 Anticorps))-exacerbated atherosclerosis and CYP1A1 plays a protective role against oral BaP (Montrer PHB2 Anticorps) toxicity in aorta
harmine and harmaline are promising candidate to inhibit TCDD-mediated induction of Cyp1a1 in mice hepatic and extrahepatic tissues
CYP1A1 and CYP1A2 (Montrer CYP1A2 Anticorps) localization into different lipid microdomains is governed by their N-terminal and internal protein regions
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
cytochrome P450 1A1
, cytochrome P450 CYP1A1
, aryl hydrocarbon hydroxylase
, cytochrome P1-450, dioxin-inducible
, cytochrome P450 form 6
, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
, cytochrome P450-C
, cytochrome P450-P1
, flavoprotein-linked monooxygenase
, xenobiotic monooxygenase
, cytochrome P1-450
, cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c)
, cytochrome P450, 1a1
, cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c)
, cytochrome P450MT2
, microsomal monooxygenase
, aromatic compound inducible
, cytochrome P450 family 1 subfamily a polypeptide 2
, cytochrome P450 subfamily I, polypeptide 1
, cytochrome P450, 1a1, aromatic compound inducible
, P-450 PHPAH1
, P450 LM6
, P450 isozyme 6
, cytochrome P-450 PHPAH1
, cytochrome P450 LM6
, cytochrome P450 isozyme 6