anti-Humain CREB1 anticorps pour Electrophoretic Mobility-Shift Assay

Recommended CREB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein 1a
  • cyclic AMP response element binding protein
  • CREB1
  • creb1
  • Creb1
  • LOC100351999
  • creb1a
  • CREB
Épitope
N-Term
142
38
38
37
22
20
15
15
15
9
8
7
7
6
6
5
5
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
548
328
298
41
38
36
30
27
26
26
19
17
15
12
7
7
7
2
1
1
1
1
Hôte
Lapin
449
101
11
1
Clonalité
Polyclonal
Conjugué
Cet anticorp CREB1 est non-conjugé
18
15
15
7
7
6
6
6
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Electrophoretic Mobility-Shift Assay (EMSA), Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
441
225
192
100
92
46
44
42
31
11
10
10
4
3
3
2
2
1
1
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N° du produit ABIN116948
495,00 €
Plus frais de livraison 40,00 € et TVA

General

Antigène CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
Épitope N-Term
(142), (38), (38), (37), (22), (20), (15), (15), (15), (9), (8), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(548), (328), (298), (41), (38), (36), (30), (27), (26), (26), (19), (17), (15), (12), (7), (7), (7), (2), (1), (1), (1), (1)
Hôte Lapin
(449), (101), (11), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp CREB1 est non-conjugé
(18), (15), (15), (7), (7), (6), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Electrophoretic Mobility-Shift Assay (EMSA), Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
(441), (225), (192), (100), (92), (46), (44), (42), (31), (11), (10), (10), (4), (3), (3), (2), (2), (1), (1)
Pubmed 1 référence disponible
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Détail du produit anti-CREB1 anticorps

Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN116948) Images
Specificité This product was prepared from monospecific antiserum by delipidation and Immunoadsorption against an E.coli lysate immobilized on agarose beads. This antibody may react non-specifically with other proteins. A partial cross-reactivity is observed against CREM-1 protein.
Immunogène CREB-1 (p43) peptide corresponding to a region near the N-terminus of the Human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Détail du antigène CREB1

Détail du produit anti-CREB1 anticorps Information d'application Stockage References for anti-CREB1 antibody (ABIN116948) Images Haut de la page
Antigène
Autre désignation CREB1 (CREB1 Antibody Extrait)
Sujet Cyclic AMP Response Element Binding protein (CREB) is a basic / leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors. Activation of CREB is dependent upon the phosphorylation of serine 133. Phosphorylation occurs via p44 / 42 MAP kinase and p90RSK and also via p38 MAP kinase and MSK 1. Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor. CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133. CREB appears to play an important role in learning and memory. CREB knock out mice show diminished learning ability.Synonyms: CREB-1, Cyclic AMP-responsive element-binding protein 1, cAMP-responsive element-binding protein 1
ID gène 1385
NCBI Accession NP_004370
UniProt P16220
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation

Information d'application

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Stockage References for anti-CREB1 antibody (ABIN116948) Images Haut de la page
Indications d'application Western Blot: This antibody was assayed against a lysate of 1 x 10^6 Raji B cells byImmunoblot and found to be reactive against CREB-1 (p43), showing a 46 kDa band at adilution of 1/500-1/1,000 followed by reaction with Peroxidase conjugated anti-Rabbit IgG(H&L) [Goat] (Cat#R1364HRP)ELISA: 1/5,000-1/25,000. Immunoprecipitation. Gelshift: This antibody was tested in Gel Supershift Assay and found to be reactive againstCREB-1 (p43) using 0.5-1.0 μL per assay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application References for anti-CREB1 antibody (ABIN116948) Images Haut de la page
Format Liquid
Concentration 2.56 mg/mL (by UV absorbance at 280 nm)
Buffer 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at -20 °C.

References for anti-CREB1 antibody (ABIN116948)

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage Images Haut de la page
Background publications

Moreno, Beresford, Louis-Plence, Morris, Boss: "CREB regulates MHC class II expression in a CIITA-dependent manner." dans: Immunity, Vol. 10, Issue 2, pp. 143-51, 1999

Images

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN116948) Haut de la page
Supplier Images
Western Blotting (WB) image for anti-CAMP Responsive Element Binding Protein 1 (CREB1) (N-Term) antibody (ABIN116948) Anti-CREB is shown to detect CREB-1 present in Raji B cell nuclear extract lysates. D...