5'-3' Exoribonuclease 1 Protéines (XRN1)

SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. De plus, nous expédions XRN1 Anticorps (27) et XRN1 Kits (4) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
XRN1 54464 Q8IZH2
Souris XRN1 XRN1 24127 P97789
XRN1 300944  
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Showing 3 out of 5 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
Escherichia coli (E. coli) Humain Inconjugué SDS-PAGE analysis of Human XRN1 Protein. 100 μg Connectez-vous pour afficher 11 to 18 Days
Escherichia coli (E. coli) Rat Inconjugué SDS-PAGE analysis of Rat XRN1 Protein. 100 μg Connectez-vous pour afficher 11 to 18 Days

XRN1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,

Rat (Rattus)

Plus protéines pour 5'-3' Exoribonuclease 1 (XRN1) partenaires d'interaction

Human 5'-3' Exoribonuclease 1 (XRN1) interaction partners

  1. Insertion of 5'-3' exoribonuclease 1 (XRN1)-resistant sequences (xrRNAs) into different reporter mRNAs allowed to monitor RNA decay activity by the nonsense-mediated mRNA decay pathway (NMD).

  2. These findings suggest that sequestration of the exoribonucleases DIS3L2 (Montrer DIS3L2 Protéines) and XRN1 to nuclear inclusions may be related to the pathogenesis of intranuclear inclusion body disease

  3. Data show that the AR-miR (Montrer MLXIP Protéines)-204-XRN1-miR (Montrer MLXIP Protéines)-34a positive feedback loop and a dual function of miR (Montrer MLXIP Protéines)-204/XRN1 axis in prostate cancer.

  4. Thus, Xrn1 is a cellular factor regulating dsRNA accumulation and dsRNA-responsive innate immune effectors.

  5. Occupation of each miR (Montrer MLXIP Protéines)-122 binding site on 5' untranslated region of the hepatitis C virus genome contributes equally and cooperatively to virus replication via protecting from Xrn1 exoribonuclease degradation.

  6. Authors conclude that Xrn1 is the dominant 5' exoribonuclease mediating decay of hepatitis C virus RNA and that miR (Montrer MLXIP Protéines)-122 provides protection against it

  7. Mouse Xrn1 plays a role in RNA turnover.

  8. Data show that 5' exonuclease (Montrer EXO1 Protéines) Xrn1 knockdown and miR (Montrer MLXIP Protéines)-122 supplementation have equal, redundant, and nonadditive effects on the rate of viral RNA decay, indicating that miR (Montrer MLXIP Protéines)-122 protects HCV RNA from 5' decay.

  9. findings reveal a role for XRN1 in decapping and provide a molecular basis for the coupling of decapping to 5'-->3' mRNA degrada

  10. LSm1 (Montrer LSM1 Protéines)-7 proteins colocalize with DCP1 (Montrer ACE Protéines),DCP2 (Montrer DCP2 Protéines) and Xrn1 in cytoplasmic foci

Mouse (Murine) 5'-3' Exoribonuclease 1 (XRN1) interaction partners

  1. XRN1 knockdown impairs the translational repression triggered by NMDA. Collectively, these observations support a role for the SX-bodies in the reversible masking and silencing of mRNAs at the synapse.

Profil protéine XRN1

Profil protéine

SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.

Gene names and symbols associated with XRN1

  • 5'-3' exoribonuclease 1 (xrn1)
  • 5'-3' exoribonuclease 1 (XRN1)
  • 5'-3' exoribonuclease 1 (Tsp_05930)
  • 5'-3' exoribonuclease 1 (Xrn1)
  • Dhm2 Protéine
  • exo Protéine
  • mXrn1 Protéine
  • RGD1309713 Protéine
  • SEP1 Protéine
  • wu:fk92c07 Protéine
  • zgc:63635 Protéine

Protein level used designations for XRN1

5'-3' exoribonuclease 1 , strand-exchange protein 1 homolog , protein Dhm2

394008 Danio rerio
424778 Gallus gallus
460744 Pan troglodytes
10911092 Trichinella spiralis
100351589 Oryctolagus cuniculus
54464 Homo sapiens
24127 Mus musculus
300944 Rattus norvegicus
477100 Canis lupus familiaris
540834 Bos taurus
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