anti-Activin A Receptor, Type IIA (ACVR2A) Anticorps

ACVR2A encodes activin A type II receptor. De plus, nous expédions Activin Receptor Type IIA Protéines (37) et Activin Receptor Type IIA Kits (15) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ACVR2A 92 P27037
ACVR2A 29263 P38444
ACVR2A 11480 P27038
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Top anti-Activin Receptor Type IIA Anticorps sur anticorps-enligne.fr

Showing 10 out of 113 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (LEFT)Western blot analysis of anti-ACVR2A Antibody (N-term) in mouse liver brain and kidney tissue lysates (35ug/lane). ACVR2A (arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of ACVR2A (arrow) using rabbit polyclonal ACVR2A Antibody 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-ACVR2A Antibody (N-term) (ABIN391160) in mouse liver brain and kidney tissue lysates (35 µg/lane). ACVR2A (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ACVR2A (arrow) using rabbit polyclonal ACVR2A Antibody (N-term) (ABIN391160). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ACVR2A gene (Lane 2) (Origene Technologies). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué IHC, WB Immunohistochemistry of paraffin-embedded human lung using ACVR2A antibody at dilution of 1:100 (x40 lens). 100 μL Connectez-vous pour afficher 16 Days
$334.02
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Stomach Tissue. 100 μg Connectez-vous pour afficher 13 to 16 Days
$350.00
Détails
Humain Lapin Inconjugué IHC (p), WB   100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Souris Lapin Inconjugué WB Mouse Acvr2a Antibody (N-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Acvr2a antibody detected the Acvr2a protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué WB Western Blot: Activin RIIA Antibody [NBP1-33601] - Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:10000. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Lapin Inconjugué IHC (p), WB Anti-ALK-1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1099919 concentration 20 ug/ml. Anti-ALK-1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1099919 concentration 20 ug/ml. 50 μL Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 20 to 21 Days
$218.90
Détails
Humain Lapin Inconjugué WB <b>Western blot</b> (WB) analyzes of ACTR-IIA antibody in extracts from rat kidney cells. 0.1 mg Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails

ACVR2A Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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Rat (Rattus)


Mouse (Murine)


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Plus d’anticorps contre Activin Receptor Type IIA partenaires d’interaction

Human Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. TGF-beta (Montrer TGFB1 Anticorps) receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.(

  2. This locus harbors an evolutionary conserved gene-desert region with non-coding intergenic sequences likely involved in regulation of protein-coding flanking genes ZEB2 (Montrer ZEB2 Anticorps) and ACVR2A. This region is intensively studied for mutations causing severe developmental/genetic disorders. Our analyses indicate a promising target region for interventions aimed to reduce risks of many major human diseases and mortality.

  3. Data suggest ALK1 (Montrer ACVRL1 Anticorps) and ACVR2A/ACVR2B (Montrer ACVR2B Anticorps), acting as BMP9 (Montrer GDF2 Anticorps) co-receptors, rearrange pro-domains of BMP9 (Montrer GDF2 Anticorps)--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  4. Activin A (Montrer INHBA Anticorps) inhibited signaling by BMP-6 (Montrer BMP6 Anticorps) and BMP-9 (Montrer GDF2 Anticorps) by competing for type 2 receptors ACVR2A and ACVR2B (Montrer ACVR2B Anticorps).

  5. Data suggest that an SNP in promoter region of ACVR2A (rs1424954, the pre-eclampsia susceptibility allele) down-regulates 1) expression of ACVR2A in trophoblasts and 2) signal transduction in response to excess activin-A (Montrer INHBA Anticorps) (as seen in pre-eclampsia).

  6. Adenomyotic tissues express high levels of myostatin (Montrer MSTN Anticorps), follistatin (Montrer FST Anticorps), and activin (Montrer Actbeta Anticorps) type II receptors.

  7. The gene ACVR2A was associated with the more severe early onset preeclampsia.

  8. For ACVR2A SNPs (rs10497025, rs1128919, rs13430086), no statistically significant difference was found between preeclampsia and control groups in terms of genotype and allele frequencies.

  9. ACVR2A was identified as a subnetwork component in functional association network analysis.

  10. ACVR2A showed statistically significant differential dose-expression relationship.

Cow (Bovine) Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. This genome-wide association study identified variants in the upstream region of ACVR2A, which were associated with female fertility in Japanese Black cattle.

Zebrafish Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. Roles in hindbrain and neural crest cell (NCC) patterning, in NCC derived pharyngeal arch cartilage and joint formation, and in tooth development.

Mouse (Murine) Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. Anti-ActRII blockade is an effective intervention against cancer cachexia providing benefit even in the presence of anti-cancer therapies.

  2. Data, including data from studies using transgenic mice, suggest that osteoblasts deficient in Acvr2A exhibit un-characteristic features; osteoclasts deficient in Acvr2A or Acvr2B (Montrer ACVR2B Anticorps) or both appear normal. Acvr2A-deficient mice exhibit significantly increased femoral trabecular bone volume at 6 weeks of age; Acvr2B (Montrer ACVR2B Anticorps)-deficient mice exhibit no significant change in any bone parameter.

  3. miR (Montrer MLXIP Anticorps)-125b regulated the activin (Montrer Actbeta Anticorps)/Smad2 (Montrer SMAD2 Anticorps) signaling in neonatal mouse ovary by directly targeting the 3'-untranslated region of activin receptor type 2a

  4. Our study shows that a miR (Montrer MLXIP Anticorps)-590/Acvr2a/Rad51b (Montrer Rad51B Anticorps) signaling axis ensures the stabilization of mESCs by balancing DNA damage repair and rapid proliferation during self-renewal.

  5. Bmpr2 (Montrer BMPR2 Anticorps) and Acvr2a normally play cell-type-specific, necessary roles in organelle biogenesis and the shutdown of developmental programs and cell division.

  6. Acvr2a is a Th17 specific gene making Th17 cells distinct from other helper T cells, Th1 (Montrer HAND1 Anticorps), Th2, and Treg.

  7. stimulates expression of APRIL via the Smad3 (Montrer SMAD3 Anticorps) and ERK (Montrer EPHB2 Anticorps)/CREB (Montrer CREB1 Anticorps) pathways in macrophages

  8. Results demonstrated that BMPRII (Montrer BMPR2 Anticorps) and ActRII are the functional type II TGF-beta (Montrer TGFB1 Anticorps) receptors in BMP-9 (Montrer GDF2 Anticorps)-induced osteogenic differentiation of C3H10T1/2 cells.

  9. The coordinated activity of ActRIIA and BMPRII (Montrer BMPR2 Anticorps) receptor subunits selectively mediates the chemotactic response to BMP7 (Montrer BMP7 Anticorps).

  10. Activin (Montrer Actbeta Anticorps) type IIB(ActRIIB (Montrer ACVR2B Anticorps)) and its subfamily receptor, Activin (Montrer Actbeta Anticorps) type IIA (ActRIIA), cooperatively mediate the Gdf11 (Montrer GDF11 Anticorps) signal in patterning the axial vertebrae

Activin Receptor Type IIA (ACVR2A) profil antigène

Profil protéine

This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Gene names and symbols associated with ACVR2A

  • activin A receptor type 2A (ACVR2A) anticorps
  • activin A receptor type 2A (acvr2a) anticorps
  • activin A receptor type 2A (Acvr2a) anticorps
  • activin A receptor type 2A L homeolog (acvr2a.L) anticorps
  • activin A receptor type 2Aa (acvr2aa) anticorps
  • activin receptor IIA (Acvr2a) anticorps
  • actr2a anticorps
  • ACTRII anticorps
  • ActrIIa anticorps
  • Acvr2 anticorps
  • acvr2a anticorps
  • rActR-II anticorps
  • TactrII anticorps
  • wu:fa02e10 anticorps
  • XSTK9 anticorps

Protein level used designations for ACVR2A

activin receptor IIA , activin receptor type-2A , activin A receptor, type IIA , ACTR-IIA , activin receptor type IIA , type II activin receptor , activin A receptor, type II , activin receptor, type IIA , ACTRIIA , activin receptor type II , activin type 2 receptor , activin receptor IIa , etID22865.9

GENE ID SPECIES
397282 Sus scrofa
476140 Canis lupus familiaris
100216172 Xenopus (Silurana) tropicalis
100224301 Taeniopygia guttata
100583170 Nomascus leucogenys
92 Homo sapiens
29263 Rattus norvegicus
281598 Bos taurus
396324 Gallus gallus
443304 Ovis aries
399283 Xenopus laevis
553359 Danio rerio
11480 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-Activin Receptor Type IIA (ACVR2A) Anticorps
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