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This protein belongs to the aldehyde dehydrogenase family of proteins. De plus, nous expédions Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (30) et Aldehyde Dehydrogenase 2 Family (Mitochondrial) Protéines (16) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 175 products:
Human Polyclonal ALDH2 Primary Antibody pour FACS, IHC (p) - ABIN1881053
Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. dans World journal of gastroenterology : WJG 2008
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Human Monoclonal ALDH2 Primary Antibody pour ELISA, WB - ABIN513240
Jeon, Jeong, Baek, Koo, Park, Yang, Yu, Kim, Pak: Network clustering revealed the systemic alterations of mitochondrial protein expression. dans PLoS computational biology 2011
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Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724795
Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. dans European heart journal 2012
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Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724796
Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes. dans Clinical toxicology (Philadelphia, Pa.) 2012
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Human Polyclonal ALDH2 Primary Antibody pour ELISA, EIA - ABIN4279257
Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. dans Alcoholism, clinical and experimental research 2009
Human Monoclonal ALDH2 Primary Antibody pour FACS, IF - ABIN2452752
Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. dans Journal of Alzheimer's disease : JAD 2014
ALDH-2 is involved in the remote ischemic preconditioning pathway.
This study aims to explore whether Parkinson's disease (PD) patients with reduced ALDH2 activity owing to the rs671 polymorphism are at risk for neuropsychological impairments.
ALDH2 polymorphisms might have different effects on the neuropsychological performance of bipolar-II patients with and without comorbid anxiety disorder
The missense variant rs671 in ALDH2 was significantly associated with serum uric acid
ALDH2 polymorphisms are significantly associated with the risk of drug addiction in the Chinese Han population.
Results suggested that styrene metabolism and styrene-induced genotoxicity could be particularly modified by ALDH2 polymorphisms. The important role of ALDH2 indicated that the accumulation of styrene glycoaldehyde, a possible genotoxic intermediate of styrene.
Alcohol consumption and ALDH2 SNP rs671 should be considered simultaneously when assessing the gastric cancer risk in a Korean population.
by an integrated analysis of the genotypes and the serum levels of APOA5, BUD13 and triglyceride, we observed that BUD13 was another potential mediator, besides APOA5, of the association between rs651821 and serum triglyceride. rs671 (ALDH2), an east Asian-specific common variant, was found to be associated with MetS (Pcombined = 9.7 x 10(-22) ) in Han Chinese
The single nuclear polymorphism rs671 in ALDH2 results in a loss of function and hence a decrease in enzyme activity leading to the accumulation of acetaldehyde. It is found in 30 to 50% of East Asians and is almost exclusively confined to these populations
Results show significant decreased risk among carriers of one or both Lys (Montrer LYZ Anticorps) alleles of rs671 for invasive mucinous ovarian cancer and for invasive and borderline mucinous tumors. Because the rs671 Lys (Montrer LYZ Anticorps) allele causes ALDH2 inactivation leading to increased acetaldehyde exposure, the observed inverse association with mucinous ovarian cancer is inferred to mean that alcohol intake may be a risk factor for this histotype.
evidence of a stronger effect for ALDH2*2(-) compared to ALDH2*2(+) with greater alcohol use when students were more exposed to peer drinking.
ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.
ACADM (Montrer ACADM Anticorps) and ALDH2 were predicted to be the target genes of miR (Montrer MYLIP Anticorps)-224
analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (Montrer ALDH1A1 Anticorps) and ALDH2
osteoblast differentiation is impaired in the absence of Aldh2 gene.
ALDH2 plays a protective role in cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and detoxifying reactive aldehydes.
Deficiency in ALDH2 activity may contribute to increased cisplatin sensitivity and cytotoxicity by producing more ROS (Montrer ROS1 Anticorps) by the treatment.
our data suggest that ALDH2 serves as an indispensable cardioprotective factor against insulin resistance-induced cardiomyopathy with a mechanism possibly associated with facilitation of the Sirt3-dependent PGC-1alpha deacetylation.
Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (Montrer MAPK1 Anticorps), NF-kappaB (Montrer NFKB1 Anticorps) and AP-1 (Montrer JUN Anticorps) signaling pathways.
ALDH2 deficiency triggers decompensation of metabolic reserves and energy metabolism disturbances in early diabetic hearts.
Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (Montrer PRKCE Anticorps)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (Montrer PPARG Anticorps) transcriptional activity.
In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.
Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2 family (mitochondrial)
, aldehyde dehydrogenase 2 family (mitochondrial)a
, aldehyde dehydrogenase 2.1
, mitochondrial aldehyde dehydrogenase 2
, mitochondrial aldehyde dehydrogenase RF2B
, aldehyde dehydrogenase
, aldehyde dehydrogenase (NAD(+))
, ALDH class 2
, aldehyde dehydrogenase, mitochondrial
, aldehyde dehydrogenase, mitochondrial-like
, acetaldehyde dehydrogenase 2
, liver mitochondrial ALDH
, nucleus-encoded mitochondrial aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2, mitochondrial
, mitochondrial aldehyde dehydrogenase