anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Anticorps

This protein belongs to the aldehyde dehydrogenase family of proteins.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain ALDH2 ALDH2 217 P05091
Anti-Rat ALDH2 ALDH2 29539 P11884
Anti-Souris ALDH2 ALDH2 11669 P47738
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Top anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Anticorps sur anticorps-enligne.fr

Showing 10 out of 194 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit <br /> Target Name: Aldh2 <br /> Sample Tissue: Mouse Small Intestine lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué FACS, IF, IHC (p), WB Western blot analysis of ALDH2 monoclonal antibody  in HepG2 cell line lysates (35ug/lane). ALDH2 (arrow) was detected using the purified mab.(4ug/ml) ALDH2 Monoclonal Antibody  immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the ALDH2 Monoclonal Antibody for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- ALDH2 Picoband antibody, IHC(P) IHC(P): Human Kidney Cancer Tissue Anti- ALDH2 Picoband antibody, Western blotting All lanes: Anti ALDH2  at 0.5ug/ml Lane 1: Rat Kidney Tissue Lysate at 50ug Lane 2: Mouse Kidney Tissue Lysate at 50ug Predicted bind size: 56KD Observed bind size: 56KD 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$245.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of ALDH2 expression in HegG2 (A), A549 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), ELISA, WB IHC-P Image ALDH2 antibody detects ALDH2 protein at mitochondria on mouse colon by immunohistochemical analysis. Sample: Paraffin-embedded mouse colon. ALDH2 antibody , dilution: 1:500. ICC/IF Image ALDH2 antibody detects ALDH2 protein at mitochondria by immunofluorescent analysis. Sample: A549 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: ALDH2 protein stained by ALDH2 antibody , diluted at 1:500. Red: phalloidin, a cytoskeleton marker, stained by phalloidin (invitrogen, A12380) diluted at 1:200. Blue: Hoechst 33342 staining. 100 μL Connectez-vous pour afficher 1 to 2 Days
$358.60
Détails
Humain Lapin Inconjugué IF, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$245.00
Détails
Humain Souris Inconjugué ICC, FACS, IHC, ELISA, WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$430.10
Détails
Humain Lapin Inconjugué IF, IHC, WB Western blot analysis of extracts of mouse lung and mouse liver  tissues, using ALDH2 antibody. 100 μL Connectez-vous pour afficher 16 Days
$334.02
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails

anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Anticorps mieux référencés

  1. Human Polyclonal ALDH2 Primary Antibody pour FACS, IHC (p) - ABIN1881053 : Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. dans World journal of gastroenterology : WJG 2008 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal ALDH2 Primary Antibody pour ELISA, WB - ABIN513240 : Jeon, Jeong, Baek, Koo, Park, Yang, Yu, Kim, Pak: Network clustering revealed the systemic alterations of mitochondrial protein expression. dans PLoS computational biology 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724795 : Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. dans European heart journal 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724796 : Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes. dans Clinical toxicology (Philadelphia, Pa.) 2012 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ALDH2 Primary Antibody pour ELISA, EIA - ABIN4279257 : Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. dans Alcoholism, clinical and experimental research 2009 (PubMed)

  6. Human Monoclonal ALDH2 Primary Antibody pour FACS, IF - ABIN2715915 : Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. dans Journal of Alzheimer's disease : JAD 2014 (PubMed)

Plus d’anticorps contre Aldehyde Dehydrogenase 2 Family (Mitochondrial) partenaires d’interaction

Rabbit Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH-2 is involved in the remote ischemic preconditioning pathway.

Human Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. rs17033 of ADH1B (Montrer ADH1B Anticorps) and rs671 of ALDH2 SNPs were associated with GC risk and smoking habit may further modify the effect of rs671. Conversely, rs4147536 of ADH1B (Montrer ADH1B Anticorps) might have a protective role in our study population.

  2. Many studies have shown that ALDH2 polymorphism is a genetic instrument for alcohol use in Mendelian randomization analysis. [review]

  3. Divers studies provide evidence that ALDH2*2 mutant allele (deficiency genotype) is present in nearly half of the East Asian population with ischemic reperfusion injury. [review]

  4. Ethnicity and ALDH2*2 altered the relationship of age of drinking initiation as a risk factor for alcohol use disorder symptoms.

  5. Studied the association between aldehyde dehydrogenase 2(ALDH2) polymorphisms, and risk and prognosis of individuals developing esophageal cancer in Xinjiang Kazak and Han populations.

  6. The ALDH2 Glu504Lys polymorphism can modify the association between alcohol intake and serum LDL cholesterol in Japanese men.

  7. A total of 394 patients with acute cerebral infarction were recruited for ALDH2 genotyping using direct sequencing. ALDH2 gene Glu504Lys was significantly associated with short-term prognosis. Short-term prognosis was assessed in accordance with the modified Ranking Scale (mRS). The genotype GA+AA of ALDH2 gene Glu504Lys locus was an independent risk factor of poor 90-day prognosis.

  8. Heavy alcohol drinking down-regulates ALDH2 gene expression level. Heavy smoking up-regulates SOD2 (Montrer SOD2 Anticorps) gene expression level in patients with head and neck squamous cell carcinoma.

  9. These results indicated that rs671 of ALDH2 may not associate with the risk of EH.

  10. This study aims to explore whether Parkinson's disease (PD) patients with reduced ALDH2 activity owing to the rs671 polymorphism are at risk for neuropsychological impairments.

Cow (Bovine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  2. ACADM (Montrer ACADM Anticorps) and ALDH2 were predicted to be the target genes of miR (Montrer MYLIP Anticorps)-224

  3. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (Montrer ALDH1A1 Anticorps) and ALDH2

Mouse (Murine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2 deficiency reduced the therapeutic effect of ALDHbr cells in the mice model of ischemic hind limb due to decreased anaerobic glycolysis and increased mitochondrial ROS (Montrer ROS1 Anticorps) generation.

  2. osteoblast differentiation is impaired in the absence of Aldh2 gene.

  3. ALDH2 plays a protective role in cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and detoxifying reactive aldehydes.

  4. Deficiency in ALDH2 activity may contribute to increased cisplatin sensitivity and cytotoxicity by producing more ROS (Montrer ROS1 Anticorps) by the treatment.

  5. our data suggest that ALDH2 serves as an indispensable cardioprotective factor against insulin resistance-induced cardiomyopathy with a mechanism possibly associated with facilitation of the Sirt3-dependent PGC-1alpha deacetylation.

  6. Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (Montrer MAPK1 Anticorps), NF-kappaB (Montrer NFKB1 Anticorps) and AP-1 (Montrer JUN Anticorps) signaling pathways.

  7. ALDH2 deficiency triggers decompensation of metabolic reserves and energy metabolism disturbances in early diabetic hearts.

  8. Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (Montrer PRKCE Anticorps)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (Montrer PPARG Anticorps) transcriptional activity.

  9. In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.

  10. Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress

Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) profil antigène

Profil protéine

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ALDH2

  • aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 (aldh2.1) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) L homeolog (aldh2.L) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (aldh2) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2) anticorps
  • aldehyde dehydrogenase 2 (aldh2) anticorps
  • aldehyde dehydrogenase (RHA1_RS43090) anticorps
  • aldehyde dehydrogenase (NAD(+)) (aldH2) anticorps
  • hypothetical protein (OE_RS03015) anticorps
  • aldehyde dehydrogenase (aldH2) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2) anticorps
  • aldehyde dehydrogenase 2, mitochondrial (Aldh2) anticorps
  • Ahd-5 anticorps
  • Ahd5 anticorps
  • ALDH-E2 anticorps
  • aldh2 anticorps
  • aldh2a anticorps
  • ALDHI anticorps
  • ALDM anticorps
  • MGC80785 anticorps
  • rf2b anticorps
  • zgc:63786 anticorps

Protein level used designations for ALDH2

aldehyde dehydrogenase 2 , aldehyde dehydrogenase 2 family (mitochondrial) , aldehyde dehydrogenase 2 family (mitochondrial)a , aldehyde dehydrogenase 2.1 , mitochondrial aldehyde dehydrogenase 2 , ALDH2B6 , mitochondrial aldehyde dehydrogenase RF2B , aldehyde dehydrogenase , aldehyde dehydrogenase (NAD(+)) , ALDH class 2 , ALDH-E2 , aldehyde dehydrogenase, mitochondrial , aldehyde dehydrogenase, mitochondrial-like , acetaldehyde dehydrogenase 2 , liver mitochondrial ALDH , nucleus-encoded mitochondrial aldehyde dehydrogenase 2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , mitochondrial aldehyde dehydrogenase , ALDHI , AHD-M1

GENE ID SPECIES
393462 Danio rerio
446857 Xenopus laevis
448267 Xenopus (Silurana) tropicalis
452252 Pan troglodytes
542567 Zea mays
713451 Macaca mulatta
4226489 Rhodococcus jostii RHA1
5776113 Staphylococcus aureus subsp. aureus USA300_TCH1516
5952690 Halobacterium salinarum R1
9005267 Rhodobacter capsulatus SB 1003
100171596 Pongo abelii
100217978 Taeniopygia guttata
100338523 Oryctolagus cuniculus
100388478 Callithrix jacchus
217 Homo sapiens
29539 Rattus norvegicus
610941 Canis lupus familiaris
733685 Sus scrofa
508629 Bos taurus
416880 Gallus gallus
11669 Mus musculus
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