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This protein belongs to the aldehyde dehydrogenase family of proteins. De plus, nous expédions Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (37) et Aldehyde Dehydrogenase 2 Family (Mitochondrial) Protéines (19) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 200 products:
Human Polyclonal ALDH2 Primary Antibody pour FACS, IHC (p) - ABIN1881053
Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. dans World journal of gastroenterology : WJG 2008
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Human Monoclonal ALDH2 Primary Antibody pour ELISA, WB - ABIN513240
Jeon, Jeong, Baek, Koo, Park, Yang, Yu, Kim, Pak: Network clustering revealed the systemic alterations of mitochondrial protein expression. dans PLoS computational biology 2011
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Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724795
Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. dans European heart journal 2012
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Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724796
Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes. dans Clinical toxicology (Philadelphia, Pa.) 2012
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Human Monoclonal ALDH2 Primary Antibody pour FACS, IF - ABIN2715915
Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. dans Journal of Alzheimer's disease : JAD 2014
Human Polyclonal ALDH2 Primary Antibody pour ELISA, EIA - ABIN4279257
Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. dans Alcoholism, clinical and experimental research 2009
ALDH-2 is involved in the remote ischemic preconditioning pathway.
Here the authors demonstrate that a missense single nucleotide polymorphism in the ALDH2 gene, rs671 (ALDH2*2), is significantly associated with hip fracture (odds ratio = 2.48, 95% confidence interval: 1.20-5.10, p = 0.021). The rs671 single nucleotide polymorphism was also significantly associated with osteoporosis development (odds ratio = 2.04, 95% confidence interval: 1.07-3.88, p = 0.040).
the mediation effects of single nucleotide polymorphisms (SNPs) in the ADH1B (Montrer ADH1B Anticorps) and ALDH2 genes on hepatocellular carcinoma, were investigated.
Three novel SNPs of ALDH2 gene were suggestively significantly associated with serum folate levels.
Coronary Artery Disease patients with mutated ALDH2 genotype are inclined to suffer with coronary artery lesions than wild type subjects.
he ALDH2 Glu504Lys polymorphism may be associated with susceptibility to colorectal cancer (meta-analysis).
rs17033 of ADH1B (Montrer ADH1B Anticorps) and rs671 of ALDH2 SNPs were associated with GC risk and smoking habit may further modify the effect of rs671. Conversely, rs4147536 of ADH1B (Montrer ADH1B Anticorps) might have a protective role in our study population.
Many studies have shown that ALDH2 polymorphism is a genetic instrument for alcohol use in Mendelian randomization analysis. [review]
Divers studies provide evidence that ALDH2*2 mutant allele (deficiency genotype) is present in nearly half of the East Asian population with ischemic reperfusion injury. [review]
Ethnicity and ALDH2*2 altered the relationship of age of drinking initiation as a risk factor for alcohol use disorder symptoms.
Studied the association between aldehyde dehydrogenase 2(ALDH2) polymorphisms, and risk and prognosis of individuals developing esophageal cancer in Xinjiang Kazak and Han populations.
ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.
ACADM (Montrer ACADM Anticorps) and ALDH2 were predicted to be the target genes of miR (Montrer MYLIP Anticorps)-224
analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (Montrer ALDH1A1 Anticorps) and ALDH2
Study found ALDH2*2 diabetic mice exhibit diastolic dysfunction and preserved systolic function at rest, similar to clinical heart failure of preserved ejection fraction.
ALDH2 deficiency reduced the therapeutic effect of ALDHbr cells in the mice model of ischemic hind limb due to decreased anaerobic glycolysis and increased mitochondrial ROS (Montrer ROS1 Anticorps) generation.
osteoblast differentiation is impaired in the absence of Aldh2 gene.
ALDH2 plays a protective role in cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and detoxifying reactive aldehydes.
Deficiency in ALDH2 activity may contribute to increased cisplatin sensitivity and cytotoxicity by producing more ROS (Montrer ROS1 Anticorps) by the treatment.
our data suggest that ALDH2 serves as an indispensable cardioprotective factor against insulin resistance-induced cardiomyopathy with a mechanism possibly associated with facilitation of the Sirt3-dependent PGC-1alpha deacetylation.
Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (Montrer MAPK1 Anticorps), NF-kappaB (Montrer NFKB1 Anticorps) and AP-1 (Montrer JUN Anticorps) signaling pathways.
ALDH2 deficiency triggers decompensation of metabolic reserves and energy metabolism disturbances in early diabetic hearts.
Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (Montrer PRKCE Anticorps)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (Montrer PPARG Anticorps) transcriptional activity.
In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2 family (mitochondrial)
, aldehyde dehydrogenase 2 family (mitochondrial)a
, aldehyde dehydrogenase 2.1
, mitochondrial aldehyde dehydrogenase 2
, mitochondrial aldehyde dehydrogenase RF2B
, aldehyde dehydrogenase
, aldehyde dehydrogenase (NAD(+))
, ALDH class 2
, aldehyde dehydrogenase, mitochondrial
, aldehyde dehydrogenase, mitochondrial-like
, acetaldehyde dehydrogenase 2
, liver mitochondrial ALDH
, nucleus-encoded mitochondrial aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2, mitochondrial
, mitochondrial aldehyde dehydrogenase