anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) Anticorps

This protein belongs to the aldehyde dehydrogenase family of proteins. De plus, nous expédions Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (37) et Aldehyde Dehydrogenase 2 Family (Mitochondrial) Protéines (19) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ALDH2 217 P05091
ALDH2 29539 P11884
ALDH2 11669 P47738
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Top anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Anticorps sur anticorps-enligne.fr

Showing 10 out of 182 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit <br /> Target Name: Aldh2 <br /> Sample Tissue: Mouse Small Intestine lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué IHC (p), WB Anti- ALDH2 Picoband antibody, IHC(P) IHC(P): Human Kidney Cancer Tissue Anti- ALDH2 Picoband antibody, Western blotting All lanes: Anti ALDH2  at 0.5ug/ml Lane 1: Rat Kidney Tissue Lysate at 50ug Lane 2: Mouse Kidney Tissue Lysate at 50ug Predicted bind size: 56KD Observed bind size: 56KD 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Souris Inconjugué FACS, IF, IHC (p), WB Western blot analysis of ALDH2 monoclonal antibody  in HepG2 cell line lysates (35ug/lane). ALDH2 (arrow) was detected using the purified mab.(4ug/ml) ALDH2 Monoclonal Antibody  immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the ALDH2 Monoclonal Antibody for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Chèvre Inconjugué ELISA, EIA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Humain Lapin Inconjugué IHC (p), WB Anti-ALDH2 antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Anti-ALDH2 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Intestine Tissue Lysate Lane 3: Rat Lung Tissue Lysate Lane 4: Rat Kidney Tissue Lysate 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Humain Souris Inconjugué ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using ALDH2 mAb against human ALDH2 recombinant protein. (Expected MW is 47.4 kDa) Dilution: 1/500 - 1/2000 100 μL Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails
Humain Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$245.00
Détails
Humain Lapin Inconjugué ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Muscle, antibody was diluted at 1:100. 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Humain Souris Inconjugué ELISA, FACS, IF/ICC, IHC, WB 100 μg Connectez-vous pour afficher 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué WB Western blot analysis of ALDH2 expression in HegG2 (A), A549 (B) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails

anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Anticorps mieux référencés

  1. Human Polyclonal ALDH2 Primary Antibody pour FACS, IHC (p) - ABIN1881053 : Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. dans World journal of gastroenterology : WJG 2008 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal ALDH2 Primary Antibody pour ELISA, WB - ABIN513240 : Jeon, Jeong, Baek, Koo, Park, Yang, Yu, Kim, Pak: Network clustering revealed the systemic alterations of mitochondrial protein expression. dans PLoS computational biology 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724795 : Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. dans European heart journal 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724796 : Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes. dans Clinical toxicology (Philadelphia, Pa.) 2012 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ALDH2 Primary Antibody pour IF, WB - ABIN388201 : Duan, Gao, Zhang, Chen, Jiang, Ji, Zhang, Chen, Yang, Su, Zhang, Liu, Zhu, Wang, Yu: Mitochondrial aldehyde dehydrogenase 2 protects gastric mucosa cells against DNA damage caused by oxidative stress. dans Free radical biology & medicine 2016 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal ALDH2 Primary Antibody pour FACS, IF - ABIN2715915 : Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. dans Journal of Alzheimer's disease : JAD 2014 (PubMed)

  7. Human Polyclonal ALDH2 Primary Antibody pour ELISA, EIA - ABIN4279257 : Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. dans Alcoholism, clinical and experimental research 2009 (PubMed)

Plus d’anticorps contre Aldehyde Dehydrogenase 2 Family (Mitochondrial) partenaires d’interaction

Rabbit Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH-2 is involved in the remote ischemic preconditioning pathway.

Human Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ardiac-specific expression of the human ALDH2 gene in mice augmented myocardial ALDH2 activity but did not improve cardiac function in response to pressure overload. After 12 weeks of transverse aortic constriction , ALDH2 transgenic mice had larger hearts than their wild-type littermates and lower capillary density

  2. Study revealed that the rs10744777 polymorphism in ALDH2 was an independent risk factor for ischemic stroke in Chinese male, but not in Chinese female.

  3. ALDH2 gene polymorphism is associated with liver diseases.

  4. In the 7,966 individuals from the Hakka population of China in this study, the frequencies of the ALDH2 genotypes *1/*1, *1/*2 and *2/*2 were 52.03%, 39.67%, and 8.30%, respectively; 47.97% of the individuals were found to carry the ALDH2*2 genotype, which was associated with a deficiency in the aldehyde dehydrogenase (ALDH2) enzyme activity.

  5. Here the authors demonstrate that a missense single nucleotide polymorphism in the ALDH2 gene, rs671 (ALDH2*2), is significantly associated with hip fracture (odds ratio = 2.48, 95% confidence interval: 1.20-5.10, p = 0.021). The rs671 single nucleotide polymorphism was also significantly associated with osteoporosis development (odds ratio = 2.04, 95% confidence interval: 1.07-3.88, p = 0.040).

  6. the mediation effects of single nucleotide polymorphisms (SNPs) in the ADH1B (Montrer ADH1B Anticorps) and ALDH2 genes on hepatocellular carcinoma, were investigated.

  7. Three novel SNPs of ALDH2 gene were suggestively significantly associated with serum folate levels.

  8. Coronary Artery Disease patients with mutated ALDH2 genotype are inclined to suffer with coronary artery lesions than wild type subjects.

  9. he ALDH2 Glu504Lys polymorphism may be associated with susceptibility to colorectal cancer (meta-analysis).

  10. rs17033 of ADH1B (Montrer ADH1B Anticorps) and rs671 of ALDH2 SNPs were associated with GC risk and smoking habit may further modify the effect of rs671. Conversely, rs4147536 of ADH1B (Montrer ADH1B Anticorps) might have a protective role in our study population.

Cow (Bovine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.

  2. ACADM (Montrer ACADM Anticorps) and ALDH2 were predicted to be the target genes of miR (Montrer MYLIP Anticorps)-224

  3. analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (Montrer ALDH1A1 Anticorps) and ALDH2

Mouse (Murine) Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) interaction partners

  1. ALDH2 activation improved ethanol-induced cardiac damage and decreased angiotensin and angiotensin II in hearts.

  2. ALDH2 overexpression inhibited the expression of c-Jun N-terminal kinase (JNK)-1 (Montrer MAPK8 Anticorps), activated protein 1 (AP-1 (Montrer JUN Anticorps)), insulin receptor substrate 1 (IRS-1 (Montrer IRS1 Anticorps)), 4- hydroxynonenal, caspase 3 (Montrer CASP3 Anticorps), transforming growth factor beta1, and collagen I and III, and enhanced Akt (Montrer AKT1 Anticorps) phosphorylation.

  3. Study found ALDH2*2 diabetic mice exhibit diastolic dysfunction and preserved systolic function at rest, similar to clinical heart failure of preserved ejection fraction.

  4. ALDH2 deficiency reduced the therapeutic effect of ALDHbr cells in the mice model of ischemic hind limb due to decreased anaerobic glycolysis and increased mitochondrial ROS (Montrer ROS1 Anticorps) generation.

  5. osteoblast differentiation is impaired in the absence of Aldh2 gene.

  6. ALDH2 plays a protective role in cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and detoxifying reactive aldehydes.

  7. Deficiency in ALDH2 activity may contribute to increased cisplatin sensitivity and cytotoxicity by producing more ROS (Montrer ROS1 Anticorps) by the treatment.

  8. our data suggest that ALDH2 serves as an indispensable cardioprotective factor against insulin resistance-induced cardiomyopathy with a mechanism possibly associated with facilitation of the Sirt3-dependent PGC-1alpha deacetylation.

  9. Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (Montrer MAPK1 Anticorps), NF-kappaB (Montrer NFKB1 Anticorps) and AP-1 (Montrer JUN Anticorps) signaling pathways.

  10. ALDH2 deficiency triggers decompensation of metabolic reserves and energy metabolism disturbances in early diabetic hearts.

Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) profil antigène

Profil protéine

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ALDH2

  • aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 (aldh2.1) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) L homeolog (aldh2.L) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (aldh2) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2) anticorps
  • aldehyde dehydrogenase 2 (aldh2) anticorps
  • aldehyde dehydrogenase (RHA1_RS43090) anticorps
  • aldehyde dehydrogenase (NAD(+)) (aldH2) anticorps
  • hypothetical protein (OE_RS03015) anticorps
  • aldehyde dehydrogenase (aldH2) anticorps
  • aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2) anticorps
  • aldehyde dehydrogenase 2, mitochondrial (Aldh2) anticorps
  • Ahd-5 anticorps
  • Ahd5 anticorps
  • ALDH-E2 anticorps
  • aldh2 anticorps
  • aldh2a anticorps
  • ALDHI anticorps
  • ALDM anticorps
  • MGC80785 anticorps
  • rf2b anticorps
  • zgc:63786 anticorps

Protein level used designations for ALDH2

aldehyde dehydrogenase 2 , aldehyde dehydrogenase 2 family (mitochondrial) , aldehyde dehydrogenase 2 family (mitochondrial)a , aldehyde dehydrogenase 2.1 , mitochondrial aldehyde dehydrogenase 2 , ALDH2B6 , mitochondrial aldehyde dehydrogenase RF2B , aldehyde dehydrogenase , aldehyde dehydrogenase (NAD(+)) , ALDH class 2 , ALDH-E2 , aldehyde dehydrogenase, mitochondrial , aldehyde dehydrogenase, mitochondrial-like , acetaldehyde dehydrogenase 2 , liver mitochondrial ALDH , nucleus-encoded mitochondrial aldehyde dehydrogenase 2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , mitochondrial aldehyde dehydrogenase , ALDHI , AHD-M1

GENE ID SPECIES
393462 Danio rerio
446857 Xenopus laevis
448267 Xenopus (Silurana) tropicalis
452252 Pan troglodytes
542567 Zea mays
713451 Macaca mulatta
4226489 Rhodococcus jostii RHA1
5776113 Staphylococcus aureus subsp. aureus USA300_TCH1516
5952690 Halobacterium salinarum R1
9005267 Rhodobacter capsulatus SB 1003
100171596 Pongo abelii
100217978 Taeniopygia guttata
100338523 Oryctolagus cuniculus
100388478 Callithrix jacchus
217 Homo sapiens
29539 Rattus norvegicus
610941 Canis lupus familiaris
733685 Sus scrofa
508629 Bos taurus
416880 Gallus gallus
11669 Mus musculus
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