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This protein belongs to the aldehyde dehydrogenase family of proteins. De plus, nous expédions Aldehyde Dehydrogenase 2 Family (Mitochondrial) Kits (30) et Aldehyde Dehydrogenase 2 Family (Mitochondrial) Protéines (16) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 175 products:
Human Polyclonal ALDH2 Primary Antibody pour FACS, IHC (p) - ABIN1881053
Guo, Wang, Liu, Chen, Qi, Guo: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. dans World journal of gastroenterology : WJG 2008
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Human Monoclonal ALDH2 Primary Antibody pour ELISA, WB - ABIN513240
Jeon, Jeong, Baek, Koo, Park, Yang, Yu, Kim, Pak: Network clustering revealed the systemic alterations of mitochondrial protein expression. dans PLoS computational biology 2011
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Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724796
Zhang, Gong, Zhang, Li, Hu: Effect of mitochondrial aldehyde dehydrogenase-2 genotype on cardioprotection in patients with congenital heart disease. dans European heart journal 2012
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Human Monoclonal ALDH2 Primary Antibody pour ICC, FACS - ABIN1724795
Bae, Kim, Shin, Kim, Shin, Kim, Kim, Yoon: The acute effects of ethanol and acetaldehyde on physiological responses after ethanol ingestion in young healthy men with different ALDH2 genotypes. dans Clinical toxicology (Philadelphia, Pa.) 2012
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Human Polyclonal ALDH2 Primary Antibody pour ELISA, EIA - ABIN4279257
Kimura, Sawayama, Matsushita, Higuchi, Kashima: Association between personality traits and ALDH2 polymorphism in Japanese male alcoholics. dans Alcoholism, clinical and experimental research 2009
Human Monoclonal ALDH2 Primary Antibody pour FACS, IF - ABIN2452752
Qiang, Xiao, Su, Wu, Tong, Liu, He: A novel mechanism for endogenous formaldehyde elevation in SAMP8 mouse. dans Journal of Alzheimer's disease : JAD 2014
ALDH-2 is involved in the remote ischemic preconditioning pathway.
Results show significant decreased risk among carriers of one or both Lys (Montrer LYZ Anticorps) alleles of rs671 for invasive mucinous ovarian cancer and for invasive and borderline mucinous tumors. Because the rs671 Lys (Montrer LYZ Anticorps) allele causes ALDH2 inactivation leading to increased acetaldehyde exposure, the observed inverse association with mucinous ovarian cancer is inferred to mean that alcohol intake may be a risk factor for this histotype.
evidence of a stronger effect for ALDH2*2(-) compared to ALDH2*2(+) with greater alcohol use when students were more exposed to peer drinking.
observed a suggestive association with delayed platelet engraftment, which warrants further examination. These results may suggest that the recipient ALDH2 genotype affects the metabolism of endogenous aldehydes, leading to a significant impact on transplantation outcomes.
These data suggest that rs671, a common functional single nucleotide polymorphism of ALDH2, is a genuine gout-associated single nucleotide polymorphism in the MYL2 (Montrer MYL2 Anticorps)-CUX2 (Montrer CUX2 Anticorps) locus and that "A" allele (Lys (Montrer LYZ Anticorps)) of rs671 plays a protective role in the development of gout.
Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (Montrer MAPK1 Anticorps), NF-kappaB (Montrer NFKB1 Anticorps) and AP-1 (Montrer FOSB Anticorps) signaling pathways.
ULK1 (Montrer ULK1 Anticorps) played a crucial role in ALDH2-offered protective effect against high glucose exposure-induced cardiomyocyte injury through regulation of autophagy
ALDH2*2 is prevalent (51.0%) among Japanese STEMI patients, and those with ALDH2*2 had higher frequencies of coronary spasm and AFS and more-severe myocardial injury compared to those with ALDH2*1/*1.
ALDH2 polymorphism might be a promising prognostic factor for Japanese patients with p16 (Montrer CDKN2A Anticorps)-negative OPC
In Japanese alcoholic men, the ALDH2*1/*1 genotype was associated with lower platelet counts for an 8-week hospital stay.
enhanced Alcohol elimination rate in ADH1B (Montrer ADH1B Anticorps)*2 carriers and the increased salivary Acetaldehyde levels in ALDH2*1/*2 carriers among intoxicated alcoholics provide possible mechanisms explaining how each genetic polymorphism a ff ects the risk of alcoholism and upper aerodigestive tract cancer.
ALDH2-catalyzed NO formation is necessary and sufficient for nitroglycerin bioactivation in vascular smooth muscle cells.
ACADM (Montrer ACADM Anticorps) and ALDH2 were predicted to be the target genes of miR (Montrer MYLIP Anticorps)-224
analysis of bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases ALDH1 (Montrer ALDH1A1 Anticorps) and ALDH2
Findings suggested that ALDH2 can influence atherosclerotic plaque development and vulnerability, and inflammation via MAPK (Montrer MAPK1 Anticorps), NF-kappaB (Montrer NFKB1 Anticorps) and AP-1 (Montrer JUN Anticorps) signaling pathways.
ALDH2 deficiency triggers decompensation of metabolic reserves and energy metabolism disturbances in early diabetic hearts.
Results show that ALDH2 is required for a normal adipogenesis and its expression in white adipose tissue is negatively correlated with obesity. Also, the study provides evidence that PKCepsilon (Montrer PRKCE Anticorps)-ALDH2 pathway positively regulates adipocyte differentiation by regulation of PPARgamma (Montrer PPARG Anticorps) transcriptional activity.
In knock-in mice in which ALDH2 enzymatic activity is maximally reduced, cardio-protection in ischemic-reperfused hearts is lacking.
Mitochondrial aldehyde dehydrogenase 2 (ALDH2) overexpression attenuates exhaustive exercise-induced mitochondrial oxidative stress
prolonged treatment of apoE(-/-) mice with Alda-1 led to the beneficial changes in the expression of genes and proteins related to neuroplasticity and mitochondrial function.
ALDH2 activation is adequate to improve the autophagy flux by reducing the carbonyl modification on SIRT1 (Montrer SIRT1 Anticorps), which in turn plays an important role in maintaining cardiac health during aging.
Our findings provide new insight into the preventive role of oesophageal ALDH2 against acetaldehyde-derived DNA damage.
High concentrations of ETBE might result in reproductive toxicity in mice with normal active ALDH2, while low active/inactive ALDH2 significantly enhanced the ETBE-induced reproductive toxicity in mice.
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2 family (mitochondrial)
, aldehyde dehydrogenase 2 family (mitochondrial)a
, aldehyde dehydrogenase 2.1
, mitochondrial aldehyde dehydrogenase 2
, mitochondrial aldehyde dehydrogenase RF2B
, aldehyde dehydrogenase
, aldehyde dehydrogenase (NAD(+))
, ALDH class 2
, aldehyde dehydrogenase, mitochondrial
, aldehyde dehydrogenase, mitochondrial-like
, acetaldehyde dehydrogenase 2
, liver mitochondrial ALDH
, nucleus-encoded mitochondrial aldehyde dehydrogenase 2
, aldehyde dehydrogenase 2, mitochondrial
, mitochondrial aldehyde dehydrogenase