anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) Anticorps

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. De plus, nous expédions Anaphase Promoting Complex Subunit 11 Protéines (9) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ANAPC11 51529 Q9NYG5
ANAPC11 498030  
ANAPC11 66156 Q9CPX9
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Showing 10 out of 116 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué EIA, IP, WB Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs). Most modifiers mature by proteolytic processing from inactive precursors (a, amino acid). Arrowheads point to the cleavage sites. Ubiquitin is expressed either as polyubiquitin or as a fusion with ribosomal proteins. Conjugation requires activating (E1) and conjugating (E2) enzymes that form thiolesters (S) with the modifiers. Modification of cullins by RUB involves SCF(SKP1/cullin-1/F-box protein) /CBC(cullin-2/elongin B/elonginC) -like E3 enzymes that are also involved in ubiquitination. In contrast to ubiquitin, the UBLs do not seem to form multi-UBL chains. UCRP(ISG15) resembles two ubiquitin moieties linked headto- tail. Whether HUB1 functions as a modifier is currently unclear. APG12 and URM1 are distinct from the other modifiers because they are unrelated in sequence to ubiquitin. Data contributed by S.Jentsch, see references below. 0.1 mL Connectez-vous pour afficher 6 to 8 Days
$533.50
Détails
Humain Souris Inconjugué IF, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$522.50
Détails
Humain Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 12 to 15 Days
$469.32
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB   0.1 mL Connectez-vous pour afficher 7 to 9 Days
$585.06
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: Apc11 Antibody [NBP1-76260] - Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 ug/mL. Western Blot: Apc11 Antibody [NBP1-76260] - Analysis of APC11 in 3T3 cell tissue lysate with APC11 antibody at (A) 1 and (B) 2 ug/mL. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails
Humain Souris Inconjugué IF, WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$507.83
Détails
Humain Lapin Inconjugué IHC (p), ELISA, WB Anti-ANAPC11 / APC11 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959612 concentration 5 ug/ml. Anti-ANAPC11 / APC11 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959612 concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Chèvre Inconjugué ELISA, WB   100 μg Connectez-vous pour afficher 6 to 7 Days
$358.02
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Apc11 Antibody [NBP1-90139] - Staining of human prostate shows moderate nuclear positivity in glandular cells. Western Blot: Apc11 Antibody [NBP1-90139] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY424181) 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Souris Inconjugué ELISA, WB Detection limit for recombinant GST tagged ANAPC11 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$450.00
Détails

ANAPC11 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-Anaphase Promoting Complex Subunit 11 Anticorps mieux référencés

  1. Human Polyclonal ANAPC11 Primary Antibody pour ELISA, IHC - ABIN4281020 : Ohta, Michel, Xiong: Association with cullin partners protects ROC proteins from proteasome-dependent degradation. dans Oncogene 2000 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre Anaphase Promoting Complex Subunit 11 partenaires d’interaction

Human Anaphase Promoting Complex Subunit 11 (ANAPC11) interaction partners

  1. siRNA targeted against Apc11 could hamper entry into G2/M phase.

  2. The authors showed, in vitro, a direct interaction between Orf virus anaphase promoting complex regulator and APC2 and its interference with interactions between APC11 and APC2.

  3. Studies indicate that APC (Montrer APC Anticorps)/C(Cdh1 (Montrer CDH1 Anticorps)) is required to maintain genomic stability.

  4. APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex.

  5. Inhibition of APC11 function by H(2)O(2) contributes to the delay in cell cycle progression through mitosis that is characteristic of cells subjected to oxidative stress

Anaphase Promoting Complex Subunit 11 (ANAPC11) profil antigène

Profil protéine

Probably catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin- protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin- conjugating E2 enzymes, it catalyzes the formation of protein- ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication. APC11 is required to recruit the ubiquitin- conjugating enzyme E2 to the APC/C.

Gene names and symbols associated with ANAPC11

  • anaphase promoting complex subunit 11 (ANAPC11) anticorps
  • anaphase promoting complex subunit 11 L homeolog (anapc11.L) anticorps
  • anaphase promoting complex subunit 11 (anapc11) anticorps
  • anaphase promoting complex subunit 11 (Anapc11) anticorps
  • anaphase-promoting complex subunit 11 (LOC615066) anticorps
  • anaphase promoting complex subunit 11 (APC11) anticorps
  • anaphase-promoting complex subunit Apc11 (apc11) anticorps
  • anaphase promoting complex subunit 11 (CAALFM_CR10610CA) anticorps
  • ubiquitin-protein ligase Anaphase Promoting Complex (APC11) anticorps
  • hypothetical protein (APC11) anticorps
  • predicted protein (APC11) anticorps
  • anaphase-promoting complex subunit 11 (LOC9320604) anticorps
  • anaphase promoting complex subunit 11 (LOC692923) anticorps
  • APC11 anaphase promoting complex subunit 11 homolog (yeast) (anapc11) anticorps
  • 1110011I19Rik anticorps
  • anapc11 anticorps
  • APC11 anticorps
  • Apc11p anticorps
  • DDBDRAFT_0187183 anticorps
  • DDBDRAFT_0231277 anticorps
  • DDB_0187183 anticorps
  • DDB_0231277 anticorps
  • R75218 anticorps
  • RGD1561880 anticorps
  • si:dkey-237i9.4 anticorps
  • zgc:153671 anticorps

Protein level used designations for ANAPC11

APC11 anaphase promoting complex subunit 11 homolog , anaphase promoting complex subunit 11 (yeast APC11 homolog) , anaphase-promoting complex subunit 11 , cyclosome subunit 11 , hepatocellular carcinoma-associated RING finger protein , anaphase promoting complex subunit 11 , anaphase promoting complex subunit 11 homolog , anaphase promoting complex subunit 11-like , Apc11p , Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition , anaphase-promoting complex subunit Apc11 , potential anaphase-promoting complex subunit Apc11 , ubiquitin-protein ligase Anaphase Promoting Complex , hypothetical protein , anaphase-promoting complex/cyclosome 11 , APC11

GENE ID SPECIES
51529 Homo sapiens
496247 Xenopus laevis
496610 Xenopus (Silurana) tropicalis
498030 Rattus norvegicus
615066 Bos taurus
851554 Saccharomyces cerevisiae S288c
2543187 Schizosaccharomyces pombe 972h-
3639005 Candida albicans SC5314
4852029 Scheffersomyces stipitis CBS 6054
5718640 Chlamydomonas reinhardtii
7203954 Phaeodactylum tricornutum CCAP 1055/1
8248072 Micromonas sp. RCC299
8625855 Dictyostelium discoideum AX4
9320604 Arabidopsis lyrata subsp. lyrata
454972 Pan troglodytes
483370 Canis lupus familiaris
616275 Bos taurus
100173127 Pongo abelii
66156 Mus musculus
692923 Bombyx mori
768140 Danio rerio
100734505 Cavia porcellus
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