Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) Kits ELISA

Required for MUC2 post-transcriptional synthesis and secretion. De plus, nous expédions AGR2 Anticorps (193) et AGR2 Protéines (22) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
AGR2 10551 O95994
AGR2 23795 O88312
AGR2 298961  
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Top AGR2 Kits ELISA sur

Showing 10 out of 17 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 6.4 pg/mL 15.6 pg/mL - 1000 pg/mL 96 Tests 13 to 16 Days
Souris 0.16 ng/mL n/a   96 Tests 15 to 18 Days
Rat 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Lapin 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Cobaye 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Singe 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
Chien 0.1 ng/mL 0.5-10 ng/mL   96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days

AGR2 Kits ELISA mieux référencés

  1. Human AGR2 Kit ELISA pour Sandwich ELISA - ABIN415308 : Kani, Malihi, Jiang, Wang, Wang, Ruderman, Agus, Mallick, Gross: Anterior gradient 2 (AGR2): blood-based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype. dans The Prostate 2013 (PubMed)
    Show all 7 Pubmed References

Plus Kits ELISA pour AGR2 partenaires d'interaction

Human Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. RAD9A drives metastasis by controlling AGR2 abundance.

  2. Excluding breast cancer, AGR2 overexpression was found to have a significant correlation with poor overall survival in other solid tumor patients.

  3. Downregulation of AGR2 by proteasome inhibition significantly enhanced antitumor activity of bevacizumab.

  4. Localization of AGR2 also has opposing effects on the Hippo pathway.

  5. AGR2 increased in TKI-resistant CML cells and its silencing restored sensitivity. Dasatinib upregulated it in K562 cells.miR-217 negatively regulated expression of AGR2 through binding its 3'-UTR. TKI treatment-induced drug resistance is correlated with a decrease of miR-217 and upregulation of AGR2. Forced expression of miR-217 led to decreased expression of AGR2.

  6. Our results highlight the potential of miR-135b-5p as a target for treating AGR2-expressing breast cancer with doxorubicin-resistance.

  7. aberrant alternative splicing of AGR2 facilitates an accumulation of the oncogenic AGR2vH isoform, in turn, contributes to the pathogenesis and severity of Cholangiocarcinoma.

  8. The secreted AGR2 may be a potential therapeutic target towards inhibiting CRC metastasis.

  9. AGR2 silencing could promote cell apoptosis and inhibit cell migration, invasion and chemotherapy resistance of pancreatic cancer cells with the involvement of the ERK/AKT axis

  10. Serum AGR2 can be used as a serum marker for clinical prognosis of nasopharyngeal carcinoma. However, serum AGR2 levels could not provide advantages in clinical practice for the differential diagnosis of cancer.

  11. The results suggest that MUC13 overexpression and loss of expression of AGR2 may predict the progression of Intraductal papillary mucinous neoplasm and an unfavorable prognosis in patients with Intraductal papillary mucinous neoplasm

  12. Cytosolic AGR2 contributed to cell metastasis ascribed to its stabilizing effect on p65 protein, which subsequently activated the NF-kappaB and facilitated epithelial to mesenchymal transition (EMT).

  13. Our data confirm AGR2 as a keeper of epithelial phenotypes, showing a positive role of AGR2 in the regulation of the epithelial marker E-cadherin and a negative effect on the mesenchymal markers vimentin and N-cadherin.

  14. Authors demonstrated that inhibition of either FOXM1 or AGR2 in human PIMAs inhibited mucinous characteristics, and reduced tumor growth and invasion. FOXM1 is necessary and sufficient to induce mucinous phenotypes in lung tumor cells in vivo.

  15. AGR2 is secreted by prostate cancer cells and induces programmed cell death in normal cells

  16. secretion and cell surface localization of AGR2 are characteristic of bladder cancer, while expression of AGR2 by itself is not.

  17. Obesity induces the expression of the mitochondrial form of arginase ARG2 in pancreatic ductal adenocarcinoma.

  18. Overexpression of AGR2 counteracts the phenotypes induced by miR-342-3p.

  19. The authors conclude that extracellular AGR2 plays an extracellular role independent of its endoplasmic reticulum function and elucidate this gain-of-function as a novel and unexpected critical extracellular matrix microenvironmental pro-oncogenic regulator of epithelial morphogenesis and tumorigenesis.

  20. High AGR2 expression is associated with ovarian cancer.

Mouse (Murine) Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. AGR2 accelerates skin wound healing through regulation of cell migration.

  2. AGR2 induced in ER-stressed and inflammatory pre-neoplastic pancreas is a potential marker of cancer progenitor cells with an important functional role in PDAC initiation.

  3. impact of AGR2 expression and EGFR signaling on tissue regeneration

  4. EGFR-mediated signaling in NCI-H460 cells is disrupted with reduced AGR2 expression.

  5. AGR2 has both intracellular and extracellular effects in the intestine

  6. Results indicate that DNA methylation within the AGR2 promoter modulates more aggressive cancer cell phenotypes.

  7. It was concluded that: the expression of AGR2 protein was significantly higher in asthmatic mice as compared with their normal counterparts; the expression was obviously related to the expression of Muc5ac protein and IL-13.

  8. Agr2 consequently serves to maintain the balance between proliferating and differentiated epithelial cells.

  9. Agr2 facilitates normal lobuloalveolar development by regulating mammary epithelial cell proliferation; we found no effects on apoptosis in Agr2(-/-) mammary epithelial cells.

  10. Loss of Foxp1/4 in the developing lung and in postnatal secretory epithelium leads to ectopic activation of the goblet cell fate program, in part, through de-repression of the protein disulfide isomerase anterior gradient 2 (Agr2).

  11. studies implicate Agr2 in intestinal homeostasis and ER stress and suggest a role in the etiology of inflammatory bowel disease

  12. AGR2 may be important for the growth and development of the intestine as well as esophageal adenocarcinomas.

  13. Overexpression of Agr2 is associated with asthma.

  14. AGR2 is a unique member of the protein disulfide isomerase family, with a specialized and nonredundant role in intestinal mucus production

Zebrafish Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) interaction partners

  1. Agr2 is essential for terminal differentiation of intestinal goblet cells in zebrafish embryos

  2. Both phylogenetic and syntenic analyses indicate that zebrafish agr2 is the orthologue of human AGR2 and mouse Agr2 genes.

AGR2 profil antigène

Antigen Summary

Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (By similarity).

Gene names and symbols associated with AGR2

  • anterior gradient 2, protein disulphide isomerase family member (AGR2) anticorps
  • anterior gradient 2 (Agr2) anticorps
  • anterior gradient 2 (agr2) anticorps
  • anterior gradient 3, protein disulphide isomerase family member (agr3) anticorps
  • anterior gradient 2, protein disulphide isomerase family member (Agr2) anticorps
  • anterior gradient 2, protein disulphide isomerase family member S homeolog (agr2.S) anticorps
  • AG2 anticorps
  • agr2 anticorps
  • agr2-A anticorps
  • Agr2h anticorps
  • bcmp11 anticorps
  • Gob-4 anticorps
  • HAG-2 anticorps
  • hag-3 anticorps
  • hag3 anticorps
  • mAG-2 anticorps
  • MGC89004 anticorps
  • PDIA17 anticorps
  • wu:fj29g05 anticorps
  • XAG-2 anticorps
  • XAgr2 anticorps
  • zgc:112187 anticorps

Protein level used designations for AGR2

AG-2 , HPC8 , anterior gradient homolog 2 , anterior gradient protein 2 homolog , protein disulfide isomerase family A, member 17 , secreted cement gland homolog , secreted cement gland protein XAG-2 homolog , anterior gradient 2 homolog , protein Gob-4 , anterior gradient 2 homologue , anterior gradient 3 , cement gland-specific protein CGS

10551 Homo sapiens
23795 Mus musculus
335616 Danio rerio
415112 Bos taurus
420596 Gallus gallus
448756 Xenopus (Silurana) tropicalis
298961 Rattus norvegicus
100174601 Pongo abelii
482333 Canis lupus familiaris
100514482 Sus scrofa
398260 Xenopus laevis
100714759 Cavia porcellus
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