anti-Ataxin 2-Binding Protein 1 (A2BP1) Anticorps

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. De plus, nous expédions Ataxin 2-Binding Protein 1 Protéines (9) et Ataxin 2-Binding Protein 1 Kits (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
A2BP1 54715 Q9NWB1
A2BP1 268859 Q9JJ43
A2BP1 302920  
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Top anti-Ataxin 2-Binding Protein 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 73 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host:  Rabbit  Target Name:  Rbfox1  Sample Type:  Mouse Testis lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-A2BP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-A2BP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-A2BP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: MCF7 cell lysate 100 μL 2 to 3 Days
$319.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE). This image was taken for the unconjugated form of this product. Other forms have not been tested. 100 μL 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis FOX1 using RAW264.7 whole cell lysates 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
REACT_Chlamydomonas reinhardtii Lapin Inconjugué IF, WB   200 μL 6 to 8 Days
$609.16
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-RBFOX1 / A2BP1 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of th ... 100 μL 11 to 14 Days
$727.83
Détails
Rat Lapin Inconjugué ICC, IHC, WB Western Blot; Sample: Mouse Heart lysate; Primary Ab: 2µg/mL Rabbit Anti-Rat A2BP1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 13 to 16 Days
$360.00
Détails

anti-Ataxin 2-Binding Protein 1 Anticorps mieux référencés

  1. Human Monoclonal A2BP1 Primary Antibody pour ICC, IF - ABIN4277039 : Gu, Bok, Yu, Caprioli, Piri: Downregulation of splicing regulator RBFOX1 compromises visual depth perception. dans PLoS ONE 2019 (PubMed)

  2. Cow (Bovine) Polyclonal A2BP1 Primary Antibody pour WB - ABIN2779139 : Fogel, Wexler, Wahnich, Friedrich, Vijayendran, Gao, Parikshak, Konopka, Geschwind: RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. dans Human molecular genetics 2012 (PubMed)

  3. Chlamydomonas reinhardtii (C. reinhardtii) Polyclonal A2BP1 Primary Antibody pour IF, WB - ABIN108467 : Terauchi, Peers, Kobayashi, Niyogi, Merchant: Trophic status of Chlamydomonas reinhardtii influences the impact of iron deficiency on photosynthesis. dans Photosynthesis research 2010 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre Ataxin 2-Binding Protein 1 partenaires d’interaction

Zebrafish Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. This study underlines that tightly regulated splicing is necessary for unconstrained cardiac function and renders the splicing regulator rbfox1 an interesting target for investigation in human heart failure and cardiomyopathy.

Chlamydomonas reinhardtii (C. reinhardtii) Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. When the abundance of the FOX1 gene product is reduced, Chlamydomonas cells grow poorly in iron-deficient medium, but not in iron-replete medium, suggesting that FOX1-dependent iron uptake is a high-affinity pathway.

Human Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. RNA-binding protein (RBFOX1) inherited polymorphism rs8051518 is not associated with splice factor mutations in myelodysplastic syndromes and myeloproliferative neoplasms.

  2. RBFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences.

  3. Low RBFOX1 expression is associated with aberrant splicing in Type 1 diabetes.

  4. Data show that while RBFOX1 and RBFOX2 do not mediate neuron-specific processing of UBE3A-ATS, these proteins play important roles in developing neurons and are not completely functionally redundant.

  5. RBFOX1 - strong candidate gene, associated with clinical features of Depression (e.g., earlier age at onset and recurrent and more severe forms of Depression). Gene expression patterns in the prefrontal and anterior cingulate cortex most closely matched the genetic findings.

  6. Our findings suggested rs17648524 (intronic RBFOX1 gene) and rs7084402 (7.5kb 5' of the BICC1 gene) showed gender-specific associations with high myopia in the Han Chinese.

  7. Report a 1.8 A X-ray structure of the free Fox-1 containing six distinct monomers. We use this and the nuclear magnetic resonance (NMR) structure of the Fox-1 protein/RNA complex for molecular dynamics (MD) analyses of the structured hydration. The individual monomers of the X-ray structure show diverse hydration patterns, however, MD excellently reproduces the most occupied hydration sites.

  8. Copy-number variations are enriched for RBFOX1 and other neurodevelopmental genes in children with developmental coordination disorder.

  9. We present a joint atomistic molecular dynamics (MD) and experimental study of two RRM-containing proteins bound with their single-stranded target RNAs, namely the Fox-1 and SRSF1 complexes.The simulations predict unanticipated specific participation of Arg142 at the protein-RNA interface of the SRFS1 complex, which is subsequently confirmed by NMR and ITC measurements

  10. FGF12, RBFOX1, and MIR302F could be important in human heterotaxy, because they were noted in multiple cases. Further investigation into genes involved in the NODAL, BMP, and WNT body patterning pathways and into the dosage effects of FGF12, RBFOX1, and MIR302F is warranted.

  11. Data indicate that multiple rare, coding variants in RBFOX1 protein associated with reduced systolic blood pressure (SBP).

  12. study identifies regulation of RNA splicing by RBFox1 as an important player in transcriptome reprogramming during heart failure that influence pathogenesis of the disease

  13. The SNP rs1478697 in A2BP1 may be associated with antipsychotic induced weight gain induced by 8-week treatment with olanzapine.

  14. This study underlines that tightly regulated splicing is necessary for unconstrained cardiac function and renders the splicing regulator rbfox1 an interesting target for investigation in human heart failure and cardiomyopathy.

  15. Cytoplasmic Rbfox1 target mRNAs were enriched in genes involved in cortical development and autism

  16. The Genome-wide association study showed a significant association for a variant within the RBFOX1 gene with generalized anxiety disorder.

  17. This study suggested that exonic RBFOX1 deletions are involved in the broad spectrum of focal and generalized epilepsies.

  18. RBFOX proteins can facilitate the splicing of micro-exons. We also found that PTBP1 likely regulates the inclusion of micro-exons, possibly by repressing the inclusion of micro-exons that are enhanced by RBFOX proteins and other splicing factors.[RBFOX]

  19. Copy Number Variations in CTNNA3 and RBFOX1 Associate with Pediatric Food Allergy

  20. Reduced RBFOX1 activity in myotonic dystrophy type 1 tissues may amplify several of the splicing alterations caused by the deficiency in MBNL1.

Mouse (Murine) Ataxin 2-Binding Protein 1 (A2BP1) interaction partners

  1. The data imply Rbfox1 may be involved in the development of cardiomyopathies via regulating the alternative splicing of CaV1.2 exon 33.

  2. Rbfox1 is a regulator in the development of cortical interneuron-subtype-specific efferent connectivity.

  3. The regulation of interneuron-specific Vamp1 by Rbfox1 contributes to performance of specialized functions in defined neuronal subtypes.

  4. Rbfox1 is expressed in all retinal ganglion cells types and in certain types of amacrine cells in the ganglion cell and inner nuclear layer. In the developing retina, Rbfox1 is present as early as E12. Although no morphological abnormalities were observed in the retinas of adult Rbfox1 KO mice 2 months after downregulation, these animals have an evident deficiency in depth perception.

  5. Study shows that Rbfox1-isoform1 plays an important role in neuronal migration and synapse network formation during corticogenesis. Defects in these critical processes may induce structural and functional defects in cortical neurons, and consequently contribute to the pathophysiology of neurodevelopmental disorders with RBFOX1 abnormalities.

  6. Upon picrotoxin treatment, Rbfox1 expression was downregulated by miR-129-5p, thereby allowing the repression of Atp2b4 and Dcx.

  7. Cytoplasmic Rbfox1 target mRNAs were enriched in genes involved in cortical development and autism

  8. Gain- and loss-of-function experiments demonstrated that Rbfox1 and Rbfox2 cooperate in promoting Mef2D splicing and subsequent myogenesis.

  9. Rbfox1 regulates RNA splicing required for skeletal muscle structure and function.

  10. Fox-1, expressed specifically in the neural cell stage, promoted Mef2c exon beta inclusion via the GCAUG.

  11. The results suggest that in neuronal tissues A2BP1 plays important roles, which are regulated in a spatiotemporal manner.

  12. our results suggest that a component of FSHD pathogenesis may arise by over-expression of FRG1, reducing Rbfox1 levels and leading to aberrant expression of an altered Calpain 3 protein through dysregulated splicing

  13. Fox-1 splices mRNAs encoding proteins important in synaptic transmission and membrane excitation.

  14. The splicing regulator Rbfox1 controls neuronal excitation in the mammalian brain.

  15. These data indicate that A2BP1 mutations may clinically affect very selective forebrain neuron types from early periods of development.

  16. The present study provides evidence that alternative neuronal nPTB and Fox-1/Fox-2 isoforms are also produced in lenses

  17. Fox-1 and Fox-2 isoforms specifically activate splicing of neuronally regulated exons, which requires UGCAUG enhancer elements

  18. These results demonstrate that the Fox protein family is playing a key role in tuning the properties of CaV1.2 calcium channels during neuronal development.

  19. Fox-1/Ataxin 2-Binding Protein 1 (A2BP1), a protein implicated in a variety of neurological diseases, can counteract the effects of chronic depolarization on splicing

Ataxin 2-Binding Protein 1 (A2BP1) profil antigène

Profil protéine

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with A2BP1

  • RNA binding protein, fox-1 homolog 1 (RBFOX1) anticorps
  • RNA binding fox-1 homolog 1 (RBFOX1) anticorps
  • RNA binding fox-1 homolog 1 (rbfox1) anticorps
  • multicopper ferroxidase (FOX1) anticorps
  • RNA binding protein, fox-1 homolog (C. elegans) 1 (Rbfox1) anticorps
  • RNA binding protein, fox-1 homolog 1 (Rbfox1) anticorps
  • 2BP1 anticorps
  • A2bp anticorps
  • A2bp1 anticorps
  • fox-1 anticorps
  • FOX1 anticorps
  • Hrnbp1 anticorps
  • zgc:103635 anticorps

Protein level used designations for A2BP1

RNA binding protein, fox-1 homolog (C. elegans) 1 , ataxin 2-binding protein 1 , RNA binding protein fox-1 homolog 1 , ataxin-2-binding protein 1 , fox-1 homolog A , hexaribonucleotide-binding protein 1 , ataxin 2 binding protein 1 , hexaribonucleotide binding protein 1 , RNA binding protein, fox-1 homolog 1

GENE ID SPECIES
416645 Gallus gallus
453899 Pan troglodytes
100357475 Oryctolagus cuniculus
449554 Danio rerio
5720109 Chlamydomonas reinhardtii
54715 Homo sapiens
521304 Bos taurus
268859 Mus musculus
302920 Rattus norvegicus
100172936 Pongo abelii
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