anti-C-Type Lectin Domain Family 4, Member E (CLEC4E) Anticorps

CLEC4E encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.

afficher tous les anticorps Gène GeneID UniProt
Anti-Humain CLEC4E CLEC4E 26253 Q9ULY5
Anti-Souris CLEC4E CLEC4E 56619 Q9R0Q8
Anti-Rat CLEC4E CLEC4E 450223 Q67EQ1
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Top anti-CLEC4E Anticorps sur anticorps-enligne.fr

Showing 10 out of 67 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué FACS, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$522.50
Détails
Humain Souris Inconjugué EIA, IF, IHC (p), WB 0.1 mL Connectez-vous pour afficher 6 to 8 Days
$412.50
Détails
Humain Souris Inconjugué ELISA, ICC, IF, IHC, IHC (p), WB Western Blot: CLEC4E Antibody (16E3) [NBP1-49311] - Cell lysates of HeLa (35ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CLEC4E (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Immunohistochemistry-Paraffin: CLEC4E Antibody (16E3) [NBP1-49311] - Paraffin embedded sections of colorectal cancer tissue were incubated with anti-human MINCLE antibody (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB). 0.1 mL Connectez-vous pour afficher 12 to 15 Days
$415.44
Détails
Humain Souris Inconjugué ELISA, WB CLEC4E monoclonal antibody (M08), clone 2D12. Western Blot analysis of CLEC4E expression in K-562. Western Blot detection against Immunogen (49.83 KDa) . 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué WB Western blot testing of human samples with CLEC4E antibody at 2ug/ml. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Souris Inconjugué IF, ELISA, WB   50 μL Connectez-vous pour afficher 7 to 9 Days
$639.83
Détails
Humain Souris Inconjugué WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$280.00
Détails
Humain Souris Alexa Fluor 488 ELISA, ICC, IF, IHC, IHC (p), WB Flow Cytometry: CLEC4E Antibody (16E3)   - An intracellular stain was performed on U-937 cells with CLEC4E Antibody (16E3) NBP1-49311AF488 (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 488. 0.1 mL Connectez-vous pour afficher 14 to 17 Days
$514.63
Détails
Humain Souris DyLight 405 ELISA, ICC, IF, IHC, IHC (p), WB   0.1 mL Connectez-vous pour afficher 14 to 17 Days
$514.63
Détails
Humain Souris Alexa Fluor 405 ELISA, ICC, IF, IHC, IHC (p), WB   0.1 mL Connectez-vous pour afficher 14 to 17 Days
$514.63
Détails

anti-CLEC4E Anticorps mieux référencés

  1. Human Monoclonal CLEC4E Primary Antibody pour ELISA, WB - ABIN565251 : Bugarcic, Hitchens, Beckhouse, Wells, Ashman, Blanchard: Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans. dans Glycobiology 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CLEC4E Primary Antibody pour IF (p), IHC (p) - ABIN1385725 : He, Xu, Li, Guo, Hu, Guo, Tang, Chen, Zhang, Tang, Zhang: Macrophage-Inducible C-Type Lectin/Spleen Tyrosine Kinase Signaling Pathway Contributes to Neuroinflammation After Subarachnoid Hemorrhage in Rats. dans Stroke 2015 (PubMed)

  3. Human Monoclonal CLEC4E Primary Antibody pour ELISA, ICC - ABIN4299166 : de Rivero Vaccari, Brand, Berti, Alonso, Bullock, de Rivero Vaccari: Mincle signaling in the innate immune response after traumatic brain injury. dans Journal of neurotrauma 2015 (PubMed)

Plus d’anticorps contre CLEC4E partenaires d’interaction

Human C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. Mincle has the ability to survey mycolate-derived glycolipids from actinomycetes, distinguishing non-pathogenic (e.g. Rhodococcus spp.) and pathogenic (e.g. Mycobacterium tuberculosis) species on the basis of alpha-chain (Montrer FCGRT Anticorps) length.

  2. combination adjuvant systems demonstrate markedly different immune activation with age, with combined DC activation via Macrophage-inducible C-type lectin and TLR7 (Montrer TLR7 Anticorps)/8 representing a novel approach to enhance the efficacy of early-life vaccines.

  3. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar lavage fluids of mice and patients with pneumococcal pneumonia

  4. a nonredundant role for Clec4e in coordinating major biological pathways involved in atherosclerosis

  5. CLEC4E expression is significantly upregulated in human masticatory mucosa during wound healing

  6. The expression of Mincle increases significantly during the early period of Aspergillus fumigatus infection, while expression of eight corresponding cytokines changes. Mincle, as a pattern recognition receptor, may play a role in the early innate immune response of the corneal resistance against fungus.

  7. Induction of Mincle by Helicobacter pylori and consequent anti-inflammatory signaling denote a bacterial survival strategy.

  8. our findings identify mincle as a contributor to the inflammatory response after traumatic brain injury

  9. Data indicate that MINCLE receptor is able to mediate the response to trehalose-6,6-dimycolate (TDM) dependent on SYK (Montrer SYK Anticorps) kinase and CARD9 (Montrer CARD9 Anticorps) protein.

  10. mincle is a fungal receptor that can suppress antifungal immunity and, as such, is a potential therapeutic target.

Mouse (Murine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. this study shows that mincle inhibits neutrophils and macrophages apoptosis in Aspergillus fumigatus keratitis

  2. Mincle is induced specifically on M1 macrophages, where Mincle-Syk (Montrer SYK Anticorps) signaling promotes and maintains inflammatory phenotypes of M1 macrophages in acute renal inflammation.

  3. work implicates a novel innate immune driver of Con (Montrer KITLG Anticorps) A hepatitis and, more broadly, suggests a potential role for Mincle in diseases governed by sterile inflammation.

  4. Mincle deletion results in TLR4 (Montrer TLR4 Anticorps)-mediated inflammation.

  5. Priming by Mincle-deficient dendritic cells (DCs).

  6. Thus, macrophage activation by the corynebacterial cell wall relies on TLR2-driven robust Mincle expression and the cooperative action of both receptors.

  7. this study shows that immune activation in vitro and in vivo by trehalose esters of simple fatty acids requires two acyl chains of length and involves Mincle

  8. Attenuated neutrophil extracellular trap formation in Mincle-/- neutrophils correlates with impaired autophagy activation in vitro and in vivo, whereas reactive oxygen species formation in these neutrophils remained intact.

  9. We here show that Mincle gene expression was induced in alveolar macrophages and neutrophils in bronchoalveolar lavage fluids of mice and patients with pneumococcal pneumonia

  10. this study shows a significant role for Mincle in Pneumocystis modulating host defense during infection

Cow (Bovine) C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. The structure of an extended portion of the extracellular domain of mincle, beyond the minimal C-type carbohydrate recognition domain, also constrains the way the binding domains may interact on the surface of macrophages.

  2. The data demonstrate how mincle bridges between the surfaces of the macrophage and the mycobacterium.

Guinea Pig C-Type Lectin Domain Family 4, Member E (CLEC4E) interaction partners

  1. the function of the guinea pig homologue of Mincle (gpMincle) and MCL (Montrer CLEC4D Anticorps) (gpMCL). gpMincle directly bound to trehalose-6,6'-dimycolate

CLEC4E profil antigène

Profil protéine

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Gene names and symbols associated with CLEC4E

  • C-type lectin domain family 4 member E (CLEC4E) anticorps
  • C-type lectin domain family 4, member e (Clec4e) anticorps
  • C-type lectin domain family 4, member E (Clec4e) anticorps
  • C-type lectin domain family 4 member E (LOC611538) anticorps
  • C-type lectin domain family 4 member E (Clec4e) anticorps
  • C86253 anticorps
  • CLEC4E anticorps
  • Clecsf9 anticorps
  • Mincle anticorps

Protein level used designations for CLEC4E

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9 , C-type lectin domain family 4 member E , C-type lectin superfamily member 9 , macrophage-inducible C-type lectin , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9 , C-type lectin, superfamily member 9 , immunoreceptor , C-type lectin domain family 4, member E

GENE ID SPECIES
26253 Homo sapiens
56619 Mus musculus
450223 Rattus norvegicus
514797 Bos taurus
611538 Canis lupus familiaris
722250 Macaca mulatta
735637 Pan troglodytes
100135686 Ovis aries
100350649 Oryctolagus cuniculus
100726838 Cavia porcellus
102121864 Macaca fascicularis
110260748 Sus scrofa
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