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CARD6 encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. De plus, nous expédions CARD6 Anticorps (106) et et beaucoup plus de produits pour cette protéine.
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Data show that NOD-like receptor signaling genes NOD2, PYCARD, CARD6, and IFI16 are upregulated in psoriatic epidermis.
The increased expression of CARD6 in esophageal squamous cell carcinoma,gastric and colorectal adenocarcinoma suggested that neoexpression of CARD6 might be related to activation of NF-kappaB pathway.
identification as a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways
CARD6 is a regulator of NF-kappaB activation that modulates the functions of RICK protein
review of the regulation of interactions of CARD6 with RICK and microtubules [review]
This gene encodes a protein that contains a caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB.
caspase recruitment domain family, member 6
, caspase recruitment domain-containing protein 6
, caspase recruitment domain-containing protein 6-like
, CARD-containing inhibitor of Nod1 and Cardiak-induced NF-kB activation
, caspase recruitment domain protein 6