anti-Chloride Intracellular Channel 1 (CLIC1) Anticorps

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. De plus, nous expédions CLIC1 Kits (12) et CLIC1 Protéines (12) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CLIC1 1192 O00299
CLIC1 114584 Q9Z1Q5
CLIC1 406864 Q6MG61
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Top anti-CLIC1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 115 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-CLIC1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-CLIC1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate Sample Type: Purified Recombinant CLIC-1 Protein Primary Dilution: 1:1000Submitted By: Harpreet Singh, University of California Los Angeles 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Liver Tissue; Lane2: Human Lung Tissue; Lane3: Human HL-60 Cells; Lane4: Human Hela Cells. 100 μg Connectez-vous pour afficher 13 to 16 Days
$350.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Lapin Inconjugué IHC (p), WB Western blot analysis of anti-CLIC1 Antibody (ABIN391851) in A375 cell line lysates (35 µg/lane). CLIC1(arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CLIC1 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Souris Inconjugué IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to CLIC1 on formalin-fixed paraffin-embedded human colon tissue. [antibody concentration 3 ug/ml] CLIC1 monoclonal antibody (M01), clone 2D4 Western Blot analysis of CLIC1 expression in HL-60 . 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CLIC1 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-CLIC1 Antibody in A375 cell line lysates (35ug/lane). CLIC1(arrow) was detected using the purified Pab (1:60dilution). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Souris Inconjugué IHC (p), ELISA, WB CLIC1 monoclonal antibody (M02), clone 3F9 Western Blot analysis of CLIC1 expression in 293 . Immunoperoxidase of monoclonal antibody to CLIC1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 0.15 ug/ml] 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 50 μg Connectez-vous pour afficher 6 to 8 Days
$445.50
Détails

CLIC1 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-CLIC1 Anticorps mieux référencés

  1. Human Polyclonal CLIC1 Primary Antibody pour WB - ABIN1881210 : Valenzuela, Martin, Por, Robbins, Warton, Bootcov, Schofield, Campbell, Breit: Molecular cloning and expression of a chloride ion channel of cell nuclei. dans The Journal of biological chemistry 1997 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CLIC1 Primary Antibody pour IF, IHC (p) - ABIN560404 : Megger, Bracht, Kohl, Ahrens, Naboulsi, Weber, Hoffmann, Stephan, Kuhlmann, Eisenacher, Schlaak, Baba, Meyer, Sitek: Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study. dans Molecular & cellular proteomics : MCP 2013 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal CLIC1 Primary Antibody pour IHC (p), ELISA - ABIN560405 : Chaze, Meunier, Chambon, Jurie, Picard: Proteome dynamics during contractile and metabolic differentiation of bovine foetal muscle. dans Animal : an international journal of animal bioscience 2012 (PubMed)

  4. Cow (Bovine) Polyclonal CLIC1 Primary Antibody pour IHC, WB - ABIN2776130 : Novarino, Fabrizi, Tonini, Denti, Malchiodi-Albedi, Lauro, Sacchetti, Paradisi, Ferroni, Curmi, Breit, Mazzanti: Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre CLIC1 partenaires d’interaction

Human Chloride Intracellular Channel 1 (CLIC1) interaction partners

  1. After CLIC1 knockdown, the expression levels of ITGalpha3, ITGalphav, ITGbeta1 and Bcl-2 (Montrer BCL2 Anticorps) mRNA and protein were decreased significantly in gastric cancer cells, as well as AKT (Montrer AKT1 Anticorps)-phosphorylation, ERK (Montrer EPHB2 Anticorps)-phosphorylation and p38 (Montrer CRK Anticorps)-phosphorylation, were reduced in vivo.

  2. The current study provides the first statistically convincing evidence that downregulation of miR (Montrer MLXIP Anticorps)-372 may occur in gallbladder cancer tissues, which may be associated with aggressive and progressive tumor behavior by affecting CLIC1 expression.

  3. The CLIC1-mediated drug resistance is achieved through positive regulation of MRP1 (Montrer MDM4 Anticorps) in choriocarcinoma.CLIC1 is highly expressed in chemoresistant choriocarcinoma.

  4. Proteomic analysis indicates that CLIC1 promotes tumorgenesis in epithelial ovarian cancer.

  5. CLIC1 is a possible tumor marker for ovarian cancer. Dendritic cells pulsed with MtHsp70 (Montrer HSPA9 Anticorps)-CLIC1 can enhance antitumor immunity against ovarian cancer, providing a novel immune therapeutic strategy.

  6. Either dysfunction or downregulation of CLIC1 can partially decrease the antineoplastic effects of metformin.

  7. The expression of CLIC1 might be closely related to the carcinogenesis, clinical biological behaviors, and prognosis of pancreatic ductal adenocarcinomas.

  8. Extracellular vesicle-mediated transfer of CLIC1 protein is a novel mechanism for the regulation of glioblastoma growth.

  9. Results indicate that CLIC1 is an important contributor to tumor invasion, metastasis, and angiogenesis.

  10. CLIC1 acts as a putative oncogene (Montrer RAB1A Anticorps) in pancreatic cancer.

Mouse (Murine) Chloride Intracellular Channel 1 (CLIC1) interaction partners

  1. Results indicate CLICs (CLIC1, CLIC4 (Montrer CLIC4 Anticorps) and CLIC5 (Montrer CLIC5 Anticorps))-dependent chloride efflux as an essential and proximal upstream event for NLRP3 (Montrer NLRP3 Anticorps) activation.

  2. We conclude that the role of CLIC1 in macrophage superoxide production is to support redistribution of NADPH oxidase (Montrer NOX1 Anticorps) to the plasma membrane, and not through major effects on ERM (Montrer ETV5 Anticorps) cytoskeleton or by acting as a plasma membrane chloride channel (Montrer CLCA1 Anticorps).

  3. Data, including data from studies in primary cells from knockout mice, suggest Clic1 and Clic4 (Montrer CLIC4 Anticorps) participate in signaling interleukin 1beta secretion and in activation of Nlrp3 (Montrer NLRP3 Anticorps) inflammasomes; in LPS (Montrer TLR4 Anticorps) macrophage activation, Clic1 and Clic4 (Montrer CLIC4 Anticorps) are translocated to nucleus/cell membranes. (Clic1 = chloride intracellular channel 1; Clic4 (Montrer CLIC4 Anticorps) = chloride intracellular channel 4 (Montrer CLIC4 Anticorps), mitochondrial; Nlrp3 (Montrer NLRP3 Anticorps) = NLR family pyrin domain containing 3 (Montrer NLRP3 Anticorps))

  4. This study demonstrates for the first time that CLIC1 is overexpressed during AS development both in vitro and in vivo and can regulate the accumulation of inflammatory cytokines and production of oxidative stress.

  5. Results indicate that CLIC1 is an important contributor to tumor invasion, metastasis, and angiogenesis.

  6. Clic1 have a role in migration and invasion in hepatocarcinoma maybe via modulating the expression of Annexin A7 (Montrer ANXA7 Anticorps) and Gelsolin (Montrer GSN Anticorps).

  7. These data all point to an important role for CLIC1 in regulating macrophage function through its ion channel activity.

  8. The down-regulation of CLIC1 enhanced proliferative activity.

  9. CLIC1 may play an important role in tumor metastasis.

  10. CLIC1 is essential for the proliferation and invasion of hepatocellular carcinoma cells.

CLIC1 profil antigène

Profil protéine

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family\; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.

Gene names and symbols associated with CLIC1

  • chloride intracellular channel 1 (clic1) anticorps
  • chloride intracellular channel 1 (CLIC1) anticorps
  • chloride intracellular channel 1 (Clic1) anticorps
  • chloride intracellular channel 1 S homeolog (clic1.S) anticorps
  • Clcp anticorps
  • CLIC1 anticorps
  • G6 anticorps
  • MGC75951 anticorps
  • MGC132377 anticorps
  • NCC27 anticorps
  • wu:fc30e04 anticorps
  • xclic1 anticorps
  • zgc:77044 anticorps

Protein level used designations for CLIC1

chloride intracellular channel 1 , RNCC protein , chloride channel ABP , chloride intracellular channel protein 1 , hRNCC , nuclear chloride ion channel 27 , nuclear chloride ion channel protein , p64CLCP , regulatory nuclear chloride ion channel protein , NCC27

GENE ID SPECIES
394484 Xenopus (Silurana) tropicalis
462564 Pan troglodytes
715446 Macaca mulatta
1192 Homo sapiens
515646 Bos taurus
100008817 Oryctolagus cuniculus
114584 Mus musculus
406864 Rattus norvegicus
324481 Danio rerio
398656 Xenopus laevis
474847 Canis lupus familiaris
594847 Sus scrofa
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