anti-ClpP Caseinolytic Peptidase, ATP-Dependent, Proteolytic Subunit Homolog (E. Coli) (CLPP) Anticorps

The protein encoded by CLPP belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. De plus, nous expédions CLPP Kits (8) et CLPP Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CLPP 53895 O88696
CLPP 8192 Q16740
CLPP 301117  
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne
  • orders@anticorps-enligne.fr

Top anti-CLPP Anticorps sur anticorps-enligne.fr

Showing 10 out of 81 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Chèvre Inconjugué IHC, ELISA, WB ABIN184946 (1 µg/mL) staining of Human Heart lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN184946 (2.5 µg/mL) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué FACS, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Chien Souris Inconjugué FACS, IF, IHC, IHC (p), WB 100 μL 11 to 14 Days
$522.50
Détails
Chien Souris Inconjugué FACS, IF, WB 100 μL 11 to 14 Days
$522.50
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB ICC/IF Image CLPP antibody [C2C3], C-term detects CLPP protein at mitochondria by immunofluorescent analysis. Sample: A431 cells were fixed in 2% paraformaldehyde/culture medium at RT for 30 min. Green: CLPP protein stained by CLPP antibody [C2C3], C-term , diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm. WB Image CLPP antibody detects CLPP protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with CLPP antibody , diluted by 1:500. 100 μL 3 to 4 Days
$466.18
Détails
Humain Souris Inconjugué ELISA, IHC, IHC (p), WB 100 μg 11 to 14 Days
$551.83
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with CLPP antibody ABIN351471 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-CLPP antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB 100 μL 11 to 14 Days
$537.17
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 to 14 Days
$484.00
Détails

anti-CLPP Anticorps mieux référencés

  1. Human Polyclonal CLPP Primary Antibody pour ICC, IF - ABIN4299242 : Jenkinson, Rehman, Walsh, Clayton-Smith, Lee, Morell, Drummond, Khan, Naeem, Rauf, Billington, Schultz, Urquhart, Lee, Berry, Hanley, Mehta, Cilliers, Clayton, Kingston, Smith, Warner, Black, Trump et al.: Perrault syndrome is caused by recessive mutations in CLPP, encoding a mitochondrial ATP-dependent chambered protease. ... dans American journal of human genetics 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CLPP Primary Antibody pour IHC (p), ELISA - ABIN563560 : Kita, Suzuki, Ochi: Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease. dans The Journal of biological chemistry 2012 (PubMed)

  3. Human Polyclonal CLPP Primary Antibody pour IHC (p), IHC - ABIN249797 : Bross, Andresen, Knudsen, Kruse, Gregersen: Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene. dans FEBS letters 1996 (PubMed)

Plus d’anticorps contre CLPP partenaires d’interaction

Mouse (Murine) ClpP Caseinolytic Peptidase, ATP-Dependent, Proteolytic Subunit Homolog (E. Coli) (CLPP) interaction partners

  1. Loss of the mitochondrial matrix protease CLPP results in a lean phenotype with improved glucose homeostasis. Whole-body CLPP-deficient mice are protected from diet-induced obesity and insulin resistance. CLPP ablation also leads to a decline in brown adipocytes function leaving mice unable to cope with a cold-induced stress due to non-functional adaptive thermogenesis.

  2. Our results show that absence of ClpP triggers compensatory responses in mice and suggest that ClpP might be dispensable for mammalian UPR(mt) initiation. Thus, we made an unexpected finding that deficiency of ClpP in mice is metabolically beneficial

  3. we demonstrate that a strong mitochondrial cardiomyopathy and diminished respiration due to DARS2 deficiency can be alleviated by the loss of CLPP, leading to an increased de novo synthesis of individual OXPHOS subunits.

  4. The authors present evidence that mammalian CLPP has an essential role in determining the rate of mitochondrial protein synthesis by regulating the level of mitoribosome assembly.

  5. Novel effects of ClpP on mitochondrial morphology, cell proliferation and protein translation pathways in muscle cells.

  6. Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors.

  7. The correlative effect of Lon and ClpP upregulation on loss of mitochondrial Fe-S proteins during the progression of the disease may suggest that Fe-S proteins are potential targets of Lon and ClpP proteases in FRDA.

Human ClpP Caseinolytic Peptidase, ATP-Dependent, Proteolytic Subunit Homolog (E. Coli) (CLPP) interaction partners

  1. Mitochondrial overexpression of human ClpP protects HeLa cells from killing by cisplatin. Overexpression of human ClpP desensitizes cells to cisplatin.

  2. Autophagy compensates impaired energy metabolism in CLPXP-deficient Podospora anserina strains and extends healthspan.

  3. we demonstrate that a strong mitochondrial cardiomyopathy and diminished respiration due to DARS2 deficiency can be alleviated by the loss of CLPP, leading to an increased de novo synthesis of individual OXPHOS subunits.

  4. ere we present eight families affected by Perrault syndrome. In five families we identified novel or previously reported variants in HSD17B4, LARS2, CLPP and C10orf2

  5. Data suggest that tumors exploit ClpXP-directed proteostasis to maintain mitochondrial bioenergetics, buffer oxidative stress, and enable metastatic competence.

  6. Data indicate endopeptidase Clp (ClpP) mutation identified in two patients with Perrault syndrome type 3 in a Turkish family.

  7. ClpP proteases from E. coli, S. aureus, and human mitochondria exhibit preferences for certain amino acids in the P1, P2, and P3 positions .

  8. Optical trapping to assay single-molecule ClpXP unfolding and translocation of substrates consisting of domains with varying stabilities and sequences; find that ClpXP unfolds most domains by a single pathway, with kinetics that depend on the native fold and structural stability.

  9. Deletion of PaClpP, leads to an unexpected healthy phenotype and increased lifespan of the fungal ageing model organism Podospora anserina and This phenotype can be reverted by expression of human ClpP.

  10. Perrault syndrome is caused by recessive mutations in CLPP.

  11. the N-terminal peptide of ClpP is a structural component of the substrate translocation channel and may play an important functional role as well

  12. hClpX can regulate the appearance of hClpP peptidase activity in mitochondria and might affect the nature of the degradation products released during ATP-dependent proteolytic cycles

  13. We propose that decreased levels of mitochondrial proteases Lon and ClpP may allow heat shock protein 60 substrate proteins to go through more folding attempts

CLPP profil antigène

Profil protéine

The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane.

Gene names and symbols associated with CLPP

  • caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) anticorps
  • caseinolytic mitochondrial matrix peptidase proteolytic subunit L homeolog (clpp.L) anticorps
  • caseinolytic mitochondrial matrix peptidase proteolytic subunit (clpp) anticorps
  • ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (Clpp) anticorps
  • caseinolytic mitochondrial matrix peptidase proteolytic subunit (Clpp) anticorps
  • AU019820 anticorps
  • CLPP anticorps
  • D17Wsu160e anticorps
  • MGC130667 anticorps
  • PRLTS3 anticorps

Protein level used designations for CLPP

ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) , endopeptidase Clp , ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog , putative ATP-dependent Clp protease proteolytic subunit, mitochondrial , caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog , caseinolytic protease, ATP-dependent, proteolytic subunit homolog , ATP-dependent protease ClpAP, proteolytic subunit, human , ClpP caseinolytic peptidase ATP-dependent, proteolytic subunit , ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog , caseinolytic peptidase, ATP-dependent, proteolytic subunit

GENE ID SPECIES
455637 Pan troglodytes
496087 Xenopus laevis
699593 Macaca mulatta
100135748 Xenopus (Silurana) tropicalis
100161357 Acyrthosiphon pisum
53895 Mus musculus
8192 Homo sapiens
301117 Rattus norvegicus
535981 Bos taurus
611738 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour anti-CLPP (CLPP) Anticorps
Avez-vous cherché autre chose?