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CCDC88B encodes a member of the hook-related protein family. De plus, nous expédions CCDC88B Anticorps (20) et CCDC88B Kits (12) et beaucoup plus de produits pour cette protéine.
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A critical function of CCDC88B in colonic inflammation and inflammatory bowel disease
results demonstrate an important role for HkRP3 in regulating the clustering of lytic granules and MTOC repositioning during the development of NK cell-mediated killing.
A genotype dataset found a sarcoidosis risk locus on chromosome 11q13.1, a risk region for Crohn disease. An allele-dependent expression of CCDC88B was found in bronchoalveolar lavage samples of German, Swedish and Czech patients with sarcoidosis.
Data show that a novel Girdin family protein, Gipie, is expressed in endothelial cells, where it interacts with GRP78 (Montrer HSPA5 Protéines), a master regulator of the UPR, and that Gipie/GRP78 (Montrer HSPA5 Protéines) interaction controls the IRE1 (Montrer ERN1 Protéines)-JNK (Montrer MAPK8 Protéines) signaling pathway.
A critical function of CCDC88B in colonic inflammation
These results identify CCDC88B as a novel and important regulator of T cell function.
This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules.
78 kDa glucose-regulated protein [GRP78]-interacting protein induced by ER stress
, GRP78-interacting protein induced by ER stress
, brain leucine zipper domain-containing protein
, brain leucine zipper protein
, coiled-coil domain-containing protein 88B
, hook-related protein 3
, coiled-coil domain containing 88