anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) Anticorps

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. De plus, nous expédions DDX21 Protéines (5) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DDX21 9188 Q9NR30
DDX21 317399 Q3B8Q1
DDX21 56200 Q9JIK5
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Top anti-DDX21 Anticorps sur anticorps-enligne.fr

Showing 10 out of 59 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Cheval Lapin Inconjugué WB WB Suggested Anti-DDX21 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  HepG2 cell lysate DDX21 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit Anti-DDX21 antibody   Paraffin Embedded Tissue: Human Lung cell Cellular Data: cilia of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-DDX21 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:1562500  Positive Control:  HepG2 cell lysate DDX21 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL 2 to 3 Days
$229.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IHC, WB ABIN6272913 at 1/100 staining Mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of HepG2 cells, using DDX21 antibody. 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB Western Blot at 1:2000 dilution Lane 1: 293 whole cell lysate Lane 2: A431 whole cell lysate Lane 3: Hela whole cell lysate Lane 4: HepG2 whole cell lysate Lane 5: HT-1080 whole cell lysate Lane 6: Jurkat whole cell lysate Lysates/proteins at 20 ug per lane. 400 μL 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué IF/ICC Immunofluorescence analysis of U2OS cells using DDX21 antibody (ABIN5973582). Blue: DAPI for nuclear staining. 100 μL 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using DDX21 antibody (ABIN5974230) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human kidney cancer using DDX21 antibody (ABIN5974230) at dilution of 1/100 (40x lens). 100 μL 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué IF Immunofluorescence analysis of U2OS cells using DDX21 antibody. 200 μL 12 to 14 Days
$438.90
Détails

anti-DDX21 Anticorps mieux référencés

  1. Human Polyclonal DDX21 Primary Antibody pour ChIP, ICC - ABIN4304615 : Obrdlik, Louvet, Kukalev, Naschekin, Kiseleva, Fahrenkrog, Percipalle: Nuclear myosin 1 is in complex with mature rRNA transcripts and associates with the nuclear pore basket. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)
    Show all 5 Pubmed References

  2. Horse (Equine) Polyclonal DDX21 Primary Antibody pour WB - ABIN2775197 : Yang, Henning, Valdez: Functional interaction between RNA helicase II/Gu(alpha) and ribosomal protein L4. dans The FEBS journal 2005 (PubMed)
    Show all 3 Pubmed References

  3. Cow (Bovine) Polyclonal DDX21 Primary Antibody pour WB - ABIN2775198 : Henning, So, Jin, Lau, Valdez: Silencing of RNA helicase II/Gualpha inhibits mammalian ribosomal RNA production. dans The Journal of biological chemistry 2003 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal DDX21 Primary Antibody pour IHC, WB - ABIN6139485 : Zhang, Zhai, Tang, Cheng, Li, Wang, Zhu: Quantitative proteome-based systematic identification of SIRT7 substrates. dans Proteomics 2017 (PubMed)

  5. Human Polyclonal DDX21 Primary Antibody pour ICC, IF - ABIN151240 : Song, Hotz-Wagenblatt, Voit, Grummt: SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability. dans Genes & development 2018 (PubMed)

Plus d’anticorps contre DDX21 partenaires d’interaction

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) interaction partners

  1. Data indicate that DEAD-box helicase 21 (DDX21) regulated Snail transcription factors (Snail) expression independent of its helicase activity.

  2. DDX21 induced gastric cancer cell growth by up-regulating levels of Cyclin D1 and CDK2.

  3. DDX21 is both an ATP-dependent and ATP-independent helicase, and both ATPase and ATP-dependent helicase activities are inhibited by Rev in a dose-dependent manner, although ATP-independent helicase activity is not. A conserved binding interaction between DDX protein's DEAD domain and Rev was identified, with Rev's nuclear diffusion inhibitory signal motif playing a significant role in binding.

  4. can drastically reduce DDX21's affinity for quadruplex, indicating that the recognition of quadruplex and specificity for telomeric repeat containing RNA quadruplex is mediated by interactions with the 2'OH of loop nucleotides

  5. Knockdown of SIRT7 leads to the same phenotype as depletion of DDX21 (i.e., increased formation of R loops and DNA double-strand breaks), indicating that SIRT7 and DDX21 cooperate to prevent R-loop accumulation, thus safeguarding genome integrity.

  6. DDX21 can suppress the expression of proteins with G4 qudruplexes in the 3 UTR of its mRNA.

  7. Results report the biogenesis and function of a box H/ACA snoRNA-ended sno-lncRNA, referred to SLERT (snoRNA-ended lncRNA enhances pre-ribosomal RNA transcription). SLERT is different from Prader-Willi Syndrome (PWS) sno-lncRNAs and plays a crucial role in rRNA biogenesis by dislodging a previously unknown clamp of DDX21 ring-shaped arrangements on Pol I complexes, thereby liberating Pol I for active rRNA transcription.

  8. In dengue virus infected cells, DDX21 translocates from nucleus to cytoplasm to active the innate immune response and thus inhibits DENV replication in the early stages of infection.

  9. DDX21 expression in breast cancer cells can promote AP-1 activity and rRNA processing, and thus, promote tumorigenesis by two independent mechanisms.

  10. Identification of several late-acting snoRNAs that bind pre-40S particles in human cells and show that their association and function in pre-40S complexes is regulated by the RNA helicase DDX21.

  11. results uncover the multifaceted role of DDX21 in multiple steps of ribosome biogenesis, and provide evidence implicating a mammalian RNA helicase in RNA modification and Pol II elongation control

  12. As sequential interaction of PB1 and NS1 with DDX21 leads to temporal regulation of viral gene expression, influenza A virus likely uses the DDX21-NS1 interaction not only to overcome restriction, but also to regulate the viral life cycle.

  13. Data indicate that DDX21, a nucleolar protein, was confirmed to associate with SET8.

  14. Studies indicated that DDX21, HNRNPC, and RCC2 were isolated from Ku86 multicomponent complex in response to DNA damage.

  15. RNA helicase II/Gualpha silencing inhibits mammalian ribosomal RNA production

  16. the function of Gu(alpha)in rRNA processing is at least partially dependent on its ability to interact with ribosomal protein L4.

  17. in addition to its transcriptional effects, c-Jun regulates rRNA processing and nucleolar compartmentalization of the rRNA processing protein DDX21

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21) interaction partners

  1. TLR4/NF-kappaB-responsive microRNAs and their potential target genes: a mouse model of skeletal muscle ischemia-reperfusion injury.

  2. a previously unknown function of the DDX21-TRIF-S100A9-TLR4-MyD88 signaling network in regulating inflammation during infection.

  3. DDX1-DDX21-DHX36 complex represents a dsRNA sensor that uses the TRIF pathway to activate type I IFN responses in the cytosol of myeloid dendritic cells

  4. RNA helicase II/Gualpha silencing inhibits mammalian ribosomal RNA production

  5. in addition to its transcriptional effects, c-Jun regulates rRNA processing and nucleolar compartmentalization of the rRNA processing protein DDX21

DDX21 profil antigène

Profil protéine

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.

Gene names and symbols associated with DDX21

  • DEAD-box helicase 21 L homeolog (ddx21.L) anticorps
  • DExD-box helicase 21 (DDX21) anticorps
  • DEAD-box helicase 21 (ddx21) anticorps
  • DEAD (Asp-Glu-Ala-Asp) box helicase 21 (ddx21) anticorps
  • DExD-box helicase 21 (Ddx21) anticorps
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 (Ddx21) anticorps
  • AI255159 anticorps
  • AL022742 anticorps
  • cb960 anticorps
  • D10Ertd645e anticorps
  • D10Wsu42e anticorps
  • DDX21 anticorps
  • Ddx21a anticorps
  • GUA anticorps
  • GURDB anticorps
  • MGC130693 anticorps
  • RH-II/GU anticorps
  • RH-II/GuA anticorps
  • wu:fi30c07 anticorps
  • wu:fi34d08 anticorps

Protein level used designations for DDX21

DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 , RNA helicase II/Gu , novel GUCT (NUC152) domain containing DEAD/DEAH box helicase , nucleolar RNA helicase 2 , DEAD box protein 21 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21 , Gu protein , RH II/Gu , RNA helicase II/Gu alpha , gu-alpha , nucleolar RNA helicase Gu , nucleolar RNA helicase II , DEAD (Asp-Glu-Ala-Asp) box polypeptide 21a , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 21 (RNA helicase II/Gu) , RH-II/Gualpha

GENE ID SPECIES
398188 Xenopus laevis
450500 Pan troglodytes
734085 Xenopus (Silurana) tropicalis
799650 Danio rerio
100072661 Equus caballus
100153111 Sus scrofa
100435678 Pongo abelii
100598637 Nomascus leucogenys
9188 Homo sapiens
476891 Canis lupus familiaris
317399 Rattus norvegicus
781917 Bos taurus
56200 Mus musculus
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