Dihydrolipoyl Transacetylase Protéines

DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC).

Qualité de données
  • 6
Type
  • 8
    Protéine
Antigène
  • 8
Réactivité
  • 5
  • 2
  • 1
Application
  • 6
  • 5
  • 4
  • 2
  • 2
Hote
  • 2
  • 2
  • 1
  • 1
  • 1
Epitope
  • 1
  • 1
  • 1
  • 1
  • 1
Conjugué
  • 1
  • 5
  • 1
  • 1
Type Proteine
  • 8
Format
  • 3
  • 2
8 Produits
Recombinant Protéine, Cellules d'insectes (Source), Pureté >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivitéHumain
Application Crys, ELISA, SDS, WB
Détails de la commande Cat. No. ABIN3085256
$9,371.15
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 60 jours ouvrables
Recombinant Protéine, Cellules d'insectes (Source), Pureté >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivitéSouris
Application Crys, ELISA, SDS, WB
Détails de la commande Cat. No. ABIN3125046
$9,371.15
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 60 jours ouvrables
Recombinant Protéine, Wheat germ (Source)
ISO
ReactivitéHumain
Application AA, AP, ELISA, WB
Détails de la commande Cat. No. ABIN1351656
$230.67
2 μg
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 11 à 12 jours ouvrables
Recombinant Protéine, Escherichia coli (E. coli) (Source), Pureté > 95 %
ReactivitéHumain
Application IP, SDS, ELISA, WB
Détails de la commande Cat. No. ABIN2120966
$640.00
Plus shipping costs $45.00
Envoi sous 15 à 18 jours ouvrables
Recombinant Protéine, Escherichia coli (E. coli) (Source), Pureté > 95 %
ReactivitéSouris
Application IP, SDS, ELISA, WB
Détails de la commande Cat. No. ABIN2120968
$736.00
Plus shipping costs $45.00
Envoi sous 15 à 18 jours ouvrables
Recombinant Protéine, HEK-293 Cells (Source), Pureté > 80 % as determined by SDS-PAGE and Coomassie blue staining
ReactivitéHumain
Application AbP, Func, PI, STD
Détails de la commande Cat. No. ABIN2719517
$888.80
20 μg
Plus frais de port $45.00 et $22.00 pour carboglace
Envoi sous 11 jours ouvrables
Recombinant Protéine, Levure (Source), Pureté > 90 %
ReactivitéRat (Rattus)
Application ELISA
Détails de la commande Cat. No. ABIN1475200
$3,589.67
1 mg
Plus shipping costs $45.00
Envoi sous 60 à 71 jours ouvrables
Recombinant Protéine
ReactivitéHumain
Détails de la commande Cat. No. ABIN1062608
$6,182.79
Plus shipping costs $45.00
Envoi sous 6 jours ouvrables
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Profil protéine Dihydrolipoyl Transacetylase (DLAT)

Profil protéine

This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.

Gene names and symbols associated with DLAT

  • midline uncoordinated (muc) anticorps
  • dihydrolipoamide S-acetyltransferase L homeolog (dlat.L) anticorps
  • dihydrolipoamide S-acetyltransferase (DLAT) anticorps
  • dihydrolipoamide S-acetyltransferase (Dlat) anticorps
  • dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (dlat) anticorps
  • dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) (Dlat) anticorps
  • 6332404G05Rik anticorps
  • anon-WO0118547.121 anticorps
  • DLAT anticorps
  • DLTA anticorps
  • Dmel\\CG5261 anticorps
  • EP(2)0816 anticorps
  • EP816 anticorps
  • PDC-E2 anticorps
  • PDCE2 anticorps
  • wu:fc14f10 anticorps
  • wu:fc21f08 anticorps
  • wu:fc86g11 anticorps
  • wu:fj57d06 anticorps

Protein level used designations for DLAT

CG5261-PA , CG5261-PB , CG5261-PC , CG5261-PD , CG5261-PE , CG5261-PF , Dihydrolipoyllysine-residue acetyltransferase , dihydrolipoamide acetyltransferase , dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) , 70 kDa mitochondrial autoantigen of primary biliary cirrhosis , E2 component of pyruvate dehydrogenase complex , M2 antigen complex 70 kDa subunit , PBC , dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex , dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial , dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial , pyruvate dehydrogenase complex component E2 , dihydrolipoyllysine-residue acetyltransferase , E2 , PDC-E2 , PDCE2 , fc86g11 , fj57d06 , no optokinetic nystagmus a , no optokinetic response b , noa , nrb

GENE ID SPECIES
34021 Drosophila melanogaster
398314 Xenopus laevis
419796 Gallus gallus
1737 Homo sapiens
489406 Canis lupus familiaris
397054 Sus scrofa
512723 Bos taurus
81654 Rattus norvegicus
100349212 Oryctolagus cuniculus
324201 Danio rerio
235339 Mus musculus