anti-G Protein-Coupled Receptor 81 (GPR81) Anticorps

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.. De plus, nous expédions G Protein-Coupled Receptor 81 Protéines (4) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
GPR81 243270  
GPR81 689936  
GPR81 27198 Q9BXC0
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Top anti-G Protein-Coupled Receptor 81 Anticorps sur anticorps-enligne.fr

Showing 10 out of 92 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué WB Western blot analysis of GPR81 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC (p) Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2091] - Analysis of anti-FKSG80 / GPR81 antibody with pituitary, anterior at 3 ug/ ml. Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2091] - Analysis of anti-FKSG80 / GPR81 antibody with human brain, glioblastoma. 0.05 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Lapin Inconjugué IHC (p) Immunohistochemistry: GPR81 Antibody [NLS2095] - Analysis of anti-FKSG80 / GPR81 antibody with pituitary. Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2095] - Human Skin, Melanoma formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Lapin Inconjugué EIA, WB Western blot analysis of GPR81 Antibody (C-term) in 293 cell line lysates (35ug/lane). This demonstrates the GPR81 antibody detected the GPR81 protein (arrow). 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Chèvre Inconjugué ELISA, WB 0.1 mg Connectez-vous pour afficher 2 to 3 Days
$481.25
Détails
Humain Chèvre Inconjugué ELISA, WB Western Blot: GPR81 Antibody [NBP1-51956] - Analysis of GPR81 in Human Liver lysate (35ug protein in RIPA buffer) using NBP1-51956 at 0.5g/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Connectez-vous pour afficher 7 to 9 Days
$485.88
Détails
Humain Lapin Inconjugué IHC (p) Anti-GPR81 antibody  ABIN1048876 IHC staining of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC (p) Anti-GPR81 antibody  ABIN1048875 IHC staining of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails
Humain Lapin Inconjugué WB Western Blot: GPR81 Antibody [NBP1-32128] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE; antibody diluted at 1:1000. Western Blot: GPR81 Antibody [NBP1-32128] - (30 ug of whole cell lysate) A: 293T 10% SDS PAGE diluted at 1:1000 100 μL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Lapin Inconjugué IHC (p) Human Colon, Epithelium (formalin-fixed, paraffin-embedded) stained with GPR81 antibody ABIN213369 at 11 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$484.00
Détails

GPR81 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Mouse (Murine) ,


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anti-G Protein-Coupled Receptor 81 Anticorps mieux référencés

  1. Human Polyclonal GPR81 Primary Antibody pour ELISA, WB - ABIN4274870 : Cai, Ren, Jin, Cheng, Kash, Chen, Wright, Taggart, Waters: Role of GPR81 in lactate-mediated reduction of adipose lipolysis. dans Biochemical and biophysical research communications 2008 (PubMed)

  2. Human Polyclonal GPR81 Primary Antibody pour IHC (p) - ABIN4315865 : Jeninga, Bugge, Nielsen, Kersten, Hamers, Dani, Wabitsch, Berger, Stunnenberg, Mandrup, Kalkhoven: Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81). dans The Journal of biological chemistry 2009 (PubMed)

Plus d’anticorps contre G Protein-Coupled Receptor 81 partenaires d’interaction

Mouse (Murine) G Protein-Coupled Receptor 81 (GPR81) interaction partners

  1. lactate can induce GPR81-independent metabolic changes that modulate macrophage pro-inflammatory activation.

  2. GPR81 expression increased during gestation, and peaked near labor. GPR81 is expressed in the uterus with high expression in myometrium. GPR81 mediates inflammation in the laboring uterus.

  3. Results indicate that lactate may aggravated ischemic brain injury by activating GPR81 and inhibition of GPR81 protects against ischemia-induced cell death via an antiapoptosis pathway

  4. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  5. Lactate negatively regulates TLR induction of the NLRP3 (Montrer NLRP3 Anticorps) inflammasome and production of IL1beta (Montrer IL1B Anticorps), via ARRB2 (Montrer ARRB2 Anticorps) and GPR81 in liver and pancreatic injury.

  6. chronic obesity reduces GPR109A (Montrer HCAR2 Anticorps) and GPR81 expression in the adipose tissue, while acute in vitro LPS (Montrer TLR4 Anticorps) treatment increases expression of GPR109A (Montrer HCAR2 Anticorps) in adipocytes and macrophages.

  7. Inflammation decreases the expression of GPR81 in adipose tissue

  8. An autocrine lactate loop mediates insulin (Montrer INS Anticorps)-dependent inhibition of lipolysis through GPR81.

  9. GPR81 couples to the Gi signaling pathway

  10. Data show that siRNA-mediated knockdown (Montrer PPARG Anticorps)of PPARgamma in differentiated 3T3-L1 adip (Montrer HCAR2 Anticorps)ocytes showe (Montrer HCAR3 Anticorps)d a significant decrease in Gpr81 protein expression.

Human G Protein-Coupled Receptor 81 (GPR81) interaction partners

  1. Findings identify GPR81 as a tumor-promoting receptor in breast cancer progression and suggest a novel mechanism that regulates GPR81-dependent activation of the PI3K (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps) signaling axis in tumor microenvironment.

  2. Activation of GPR81 decreases intracellular cAMP levels and inhibits PKA activity, leading to activation of TAZ (Montrer TAZ Anticorps) and upregulation of PD-L1 (Montrer CD274 Anticorps). This study reveals a critical role for lactate in the immune checkpoint pathway and an unexpected function of TAZ (Montrer TAZ Anticorps) in tumor evasion of the T-cell-mediated immune response.

  3. Lactate receptor/HCAR1 expression in cervical carcinoma cells may contribute to the modulation of cellular DNA repair mechanisms.

  4. HCA1/3 are necessary for breast cancer cells to balance lipid/fatty acid metabolism.

  5. HCAR1 and monocarboxylate transporters activity is required for the L- and D-lactate-mediated enhancement of DNA repair and of HeLa cell survival.

  6. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  7. Data support that GPR81 is important for cancer cell regulation of lactate transport mechanisms.

  8. Lactate negatively regulates TLR induction of the NLRP3 (Montrer NLRP3 Anticorps) inflammasome and production of IL1beta (Montrer IL1B Anticorps), via ARRB2 (Montrer ARRB2 Anticorps) and GPR81 in liver and pancreatic injury.

  9. demonstrated that the C165-E166-S167-F168 motif at the second extracellular loop is critical for GPR81 function, and the conserved six Cys (Montrer DNAJC5 Anticorps) residues at the extracellular regions are necessary for GPR81 function

  10. GPR81 with relatively restricted expression in the adipose tissues functions as a receptor for lactate and can mediate an anti-lipolytic effect of lactate.

G Protein-Coupled Receptor 81 (GPR81) profil antigène

Profil protéine

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.

Gene names and symbols associated with GPR81

  • hydroxycarboxylic acid receptor 1 (HCAR1) anticorps
  • hydroxycarboxylic acid receptor 1-1 (hcar1-1) anticorps
  • hydrocarboxylic acid receptor 1 (Hcar1) anticorps
  • G protein-coupled receptor 81 (Gpr81) anticorps
  • GPR81 anticorps
  • gpr81-1 anticorps
  • GPR104 anticorps
  • HCA1 anticorps
  • Hcar1 anticorps
  • LACR1 anticorps
  • TA-GPCR anticorps

Protein level used designations for GPR81

G protein-coupled receptor 81 , G-protein coupled receptor 81 , hydroxycarboxylic acid receptor 1 , G protein-coupled receptor 104 , G-protein coupled receptor 104 , T-cell activation G protein-coupled receptor , hydroxy-carboxylic acid receptor 1 , lactate receptor 1

GENE ID SPECIES
452331 Pan troglodytes
538759 Bos taurus
570755 Danio rerio
702825 Macaca mulatta
100345808 Oryctolagus cuniculus
243270 Mus musculus
689936 Rattus norvegicus
486252 Canis lupus familiaris
27198 Homo sapiens
100153287 Sus scrofa
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