Glycine Transporter 1 Protéines (GLYT1)

transporter for glycine which is dependent on external Na+ and Cl- and may be involved in inhibitory glycinergic transmission [RGD, Feb 2006].. De plus, nous expédions Glycine Transporter 1 Anticorps (33) et Glycine Transporter 1 Kits (5) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
GLYT1 6536 P48067
GLYT1 14664 P28571
Rat GLYT1 GLYT1 116509 P28572
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Showing 3 out of 4 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 50 Days
$6,869.04
Détails
Cellules d'insectes Souris rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Connectez-vous pour afficher 60 to 65 Days
$7,639.51
Détails
Escherichia coli (E. coli) Humain Inconjugué   100 μg Connectez-vous pour afficher 11 to 18 Days
$582.75
Détails

GLYT1 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human ,
,
Mouse (Murine)

Plus protéines pour Glycine Transporter 1 (GLYT1) partenaires d'interaction

Human Glycine Transporter 1 (GLYT1) interaction partners

  1. Whole-exome sequencing revealed a novel homozygous missense variant in exon 9 of SLC6A9 NM_201649.3: c.1219 A>G (p.Ser407Gly) that segregates with the disease within the family. In murine model, knockout of Slc6a9 is associated with equivalent phenotype of non-ketotic hyperglycinemia (NKH (Montrer AMT Protéines)), namely respiratory distress and hypotonia.

  2. This study demonstrates that lack of GLYT1 le (Montrer MGAT1 Protéines)ads to a distinct human neurological syndrome hallmarked by m (Montrer CSF2 Protéines)ildly elevated cerebrospinal fluid glycine and normal serum glycine.

  3. Study found that temporal lobe epilepsy is asso (Montrer MGAT1 Protéines)ciated with increased levels of GlyT1

  4. Human positron-emission tomography studies determine the test-retest reproducibility of [11C]GSK931145, a ligand which readily enters the brain, displaying a heterogeneous uptake which corresponds well with the known distribution of GlyT-1 (Montrer MGAT1 Protéines).

  5. metabolic functions of GLYT1 (Montrer MGAT1 Protéines) in intestine: metabolism/regulation of glycine/glutathione; role in response to physiological stress (e.g., oxidative stress); possible role in pathophysiology/therapy of inflammatory bowel diseases [REVIEW]

  6. Genetic variation of the glycine transporter 1 gene may contribute to individual vulnerability to methamphetamine dependence and psychosis.

  7. SLC6A9 gene is associated with schizophrenia.

  8. the results suggest that GLYT1 (Montrer MGAT1 Protéines) and membrane rafts are co-localized in the membrane, and that this influences the rate of glycine transport.

  9. association between SLC6A9 SNPs and essential hypertension in a Japanese population, suggesting that SLC6A9 is a susceptibility locus for essential hypertension.

Mouse (Murine) Glycine Transporter 1 (GLYT1) interaction partners

  1. Whole-exome sequencing revealed a novel homozygous missense variant in exon 9 of SLC6A9 NM_201649.3: c.1219 A>G (p.Ser407Gly) that segregates with the disease within the family. In murine model, knockout of Slc6a9 is associated with equivalent phenotype of non-ketotic hyperglycinemia (NKH (Montrer GCSH Protéines)), namely respiratory distress and hypotonia.

  2. pharmacologic or genetic abolishment of GlyT1 activity in mice leads to mildly elevated glycine in the CSF (Montrer CSF2 Protéines) but not in blood

  3. Study demonstrated a biphasic response of GlyT1 expression during epileptogenesis with initial downregulation of GlyT1 after epileptogenesis-precipitating seizures followed by sustained pathological overexpression of GlyT1 in chronic epilepsy

  4. Results suggest that the excessive GAT-1 and GlyT-1/2 heterotransporter-mediated Glu (Montrer GCG Protéines) release, in the spinal cord of SOD1 (Montrer SOD1 Protéines)(G93A) mice, is due to the heterotransporter over-expression at the nerve terminal membrane, promoted by the excessive Glu (Montrer GCG Protéines) exocytosis

  5. the possible involvement of calmodulin or calmodulin-like (Montrer KRIT1 Protéines) interactions in the regulation of GlyT1 C-mediated transporter trafficking

  6. Disruption of GlyT1 in forebrain neurons does not increase the risk of forming spurious and potentially maladaptive fear associations.

  7. The demonstrated increased sensitivity to the effect of CS-US temporal discontiguity further highlights the importance of GlyT1-dependent mechanisms in the regulation of associative learning.

  8. This study demonistrated that the GlyT1-/+ subjects quickly reached a plateau response to AMPH (Montrer AMPH Protéines), which remained stable during drug withdrawal

  9. These alterations in the activities and expression profiles of the GlyTs suggest that the contributions of GlyT1 and GlyT2 (Montrer SLC6A5 Protéines) to the regulation of extracellular glycine concentrations at glycinergic synapses changes during development.

  10. This study demonistrated that forebrain neuronal glycine transporter 1 deficine not cause working memory disorders.

Zebrafish Glycine Transporter 1 (GLYT1) interaction partners

  1. A missense mutation in the slc6a9 gene that encodes a glycine transporter (GlyT1) was identified as the cause of the sho (Montrer SPRN Protéines) phenotype,attributable to elevated extracellular glycine within the CNS.

  2. glycine tolerance and reduced glycine receptor (Montrer GLRB Protéines) expression in GlyT1 mutants reflect compensatory mechanisms for functional recovery from excess nervous system inhibition

Profil protéine Glycine Transporter 1 (GLYT1)

Profil protéine

transporter for glycine which is dependent on external Na+ and Cl- and may be involved in inhibitory glycinergic transmission

Gene names and symbols associated with GLYT1

  • solute carrier family 6 member 9 (SLC6A9)
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (Slc6a9)
  • solute carrier family 6 member 9 (Slc6a9)
  • glycine transporter 1 (glyt1)
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (SLC6A9)
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (slc6a9)
  • glyT-1 Protéine
  • GLYT-1b Protéine
  • glyT1 Protéine
  • slc6a9 Protéine

Protein level used designations for GLYT1

glyT-1 , sodium- and chloride-dependent glycine transporter 1 , solute carrier family 6 member 9 , glycine transporter 1 , glycine transporter variant 1a , Sodium- and chloride-dependent glycine transporter 1 , Sho , shocked

GENE ID SPECIES
6536 Homo sapiens
14664 Mus musculus
116509 Rattus norvegicus
100126661 Xenopus laevis
282368 Bos taurus
100720563 Cavia porcellus
494490 Danio rerio
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