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The protein encoded by HDLBP binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. De plus, nous expédions High Density Lipoprotein Binding Protein Kits (14) et High Density Lipoprotein Binding Protein Protéines (3) et beaucoup plus de produits pour cette protéine.
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Cow (Bovine) Polyclonal HDLBP Primary Antibody pour WB - ABIN2778934
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... dans Molecular systems biology 2007
vigilin has been shown to bind over 700 mRNAs and has been associated with cancer progression and cardiovascular disease.
this study shows that vigilin (HDLBP) binds and negatively regulates MICB (Montrer MICB Anticorps) expression through its 5'UTR (Montrer UTS2R Anticorps), and that vigilin downregulation in target cells leads to NK cell activation against said target cells
progressively upregulated vigilin may serve as a molecular risk marker for hepatocellular carcinoma development, and targeting vigilin may help to inhibit hepatocellular carcinoma cell growth, survival and migration.
CTCF (Montrer CTCF Anticorps) may regulate vigilin behavior and thus indirectly influence the binding of HP1alpha (Montrer CBX5 Anticorps) to the satellite 2 locus
Vigilin may have a relationship with hepatocellular carcinoma progression and proliferation.
identified a competition for binding the 69-nt sequence, through which vigilin and HuR (Montrer ELAVL1 Anticorps) exert opposing effects on c-fms (Montrer CSF1R Anticorps) expression, suggesting a role for vigilin in suppression of breast cancer progression
Expression profiles of human VIGILIN, H19, and IGF2 mRNA increased with cell-cycle prograssion.
RNA interference studies indicate vigilin is essential for cell viability but is not a global regulator of translation.
evidence that vigilin is bound to the ribosomal complex.
C-terminal domain of human vigilin binds to the histone methyltransferase SUV39H1 (Montrer SUV39H1 Anticorps) in vivo;a new model for vigilin-mediated, RNA-induced gene silencing is presented.
The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. Three transcript variants encoding two different isoforms have been found for this gene.
, high density lipoprotein-binding protein
, high density lipoprotein binding protein (vigilin)
, high density lipoprotein binding protein
, HDL binding protein
, lipoprotein-binding protein
, high density lipoprotein (HDL) binding protein
, high density lipoprotein-binding protein (vigilin)