Intercellular Adhesion Molecule 4 (ICAM4) Kits ELISA

ICAM4 encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. De plus, nous expédions ICAM4 Anticorps (68) et ICAM4 Protéines (13) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ICAM4 3386 Q14773
ICAM4 78369 Q9ERM2
Anti-Rat ICAM4 ICAM4 298702  
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Top ICAM4 Kits ELISA sur anticorps-enligne.fr

Showing 3 out of 9 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 0.063 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$700.00
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Souris 0.059 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$720.00
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Lapin 0.1 ng/mL 0.5 ng/mL - 10 ng/mL   96 Tests 15 to 18 Days
$707.14
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Plus Kits ELISA pour ICAM4 partenaires d'interaction

Human Intercellular Adhesion Molecule 4 (ICAM4) interaction partners

  1. the effect of modulation of the cAMP-PKA-dependent pathway on ICAM-4 receptor activation

  2. Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM, ICAM-4 and LFA-3, both in percentage of positive cells and in surface density.

  3. ICAM-1 and ICAM-4 play roles in host cell invasion by M. tuberculosis and P. falciparum, respectively.

  4. Seven variant ICAM4 alleles were found, distinct from the wild-type ICAM4 allele (GenBank KF712272), known as LW*05 and encoding LW(a) .

  5. Data from differentiating cultured erythroid precursor cells suggest that RhAG (Rh-associated glycoprotein) knockdown abolishes Rh blood group expression (ICAM4; RhoD [ras homolog family member D]; CD47 Rh-related antigen) in erythroid cells.

  6. Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.

  7. In a transgenic mouse model of sickle cell disease ICAM-4 is implicated in abnormal adhesiveness of erythrocytes to endothelium.

  8. LWa allele occurs with incidence of 100% of donors in this study, while LWb allele has not been found in Chinese population.

  9. ICAM-4 as the first red blood cells protein ligand of platelets that may have relevant physiological significance

  10. binds to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins

  11. 12 single amino-acid changes in ICAM4 affected the interaction of ICAM-4 with alpha(V) integrins

  12. LW on sickle but not on normal erythrocytes undergoes increased PKA-dependent serine phosphorylation as a result of activation. The major counter receptor for LW was identified as the alphavbeta3 integrin on ECs

  13. Different integrins bind to different but partly overlapping sites on ICAM4, and ICAM4 may accommodate multiple integrin receptors present on leukocytes, platelets and endothelial cells.

  14. Review. LW antigen contributes to RBC adhesion, thrombosis, and (in sickle cell disease) vaso-occlusion.

  15. We show that ICAM-4 functions as a ligand for the monocyte/macrophage-specific CD11c/CD18. Deletion of the individual immunoglobulin domains of ICAM-4 demonstrated that both its domains contain binding sites for CD11c/CD18.

  16. LW play potentially pathophysiological roles in sickle cell disease

Mouse (Murine) Intercellular Adhesion Molecule 4 (ICAM4) interaction partners

  1. A novel second splice cDNA encodes an ICAM-4 isoform lacking the membrane-spanning domain. Erythroblasts express both isoforms. This new isoform, ICAM-4S, may modulate membrane-associated ICAM-4 binding & regulate erythroblast molecular attachments.

  2. ICAM-4 is critical in erythroblastic island formation via ICAM-4/alpha(V) adhesion

ICAM4 profil antigène

Antigen Summary

This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100\; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ICAM4

  • intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4) anticorps
  • intercellular adhesion molecule 4, Landsteiner-Wiener blood group (Icam4) anticorps
  • intercellular adhesion molecule 4 (ICAM4) anticorps
  • 1810015M19Rik anticorps
  • Cd242 anticorps
  • ICAM-4 anticorps
  • LW anticorps

Protein level used designations for ICAM4

CD242 antigen , LW blood group protein , Landsteiner-Wiener blood group antigen a , Landsteiner-Wiener blood group glycoprotein , intercellular adhesion molecule 4 , intercellular adhesion molecule 4 (LW blood group) , LW glycoprotein , Landsteiner-Wiener blood group protein , intercellular adhesion molecule 4, Landsteiner-Wiener blood group

GENE ID SPECIES
3386 Homo sapiens
78369 Mus musculus
455698 Pan troglodytes
514873 Bos taurus
611265 Canis lupus familiaris
100516594 Sus scrofa
298702 Rattus norvegicus
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