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The protein encoded by IL17A is a proinflammatory cytokine produced by activated T cells. De plus, nous expédions IL17A Kits (114) et IL17A Protéines (94) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 513 products:
Human Polyclonal IL17A Primary Antibody pour CyTOF, FACS - ABIN4900592
Todd, Simpson, Estis, Torres, Wub: Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. dans Cytokine 2013
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Mouse (Murine) Polyclonal IL17A Primary Antibody pour CyTOF, FACS - ABIN4899637
Otani, Watanabe, Tanigawa, Okazaki, Yamagami, Watanabe, Tominaga, Fujiwara, Oshitani, Arakawa: Anti-inflammatory effects of IL-17A on Helicobacter pylori-induced gastritis. dans Biochemical and biophysical research communications 2009
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Human Monoclonal IL17A Primary Antibody pour Neut - ABIN786714
Aarvak, Chabaud, Miossec, Natvig: IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. dans Journal of immunology (Baltimore, Md. : 1950) 1999
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Human Monoclonal IL17A Primary Antibody pour - ABIN786713
Chabaud, Durand, Buchs, Fossiez, Page, Frappart, Miossec: Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. dans Arthritis and rheumatism 1999
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Human Monoclonal IL17A Primary Antibody pour Neut - ABIN786712
Chabaud, Fossiez, Taupin, Miossec: Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. dans Journal of immunology (Baltimore, Md. : 1950) 1998
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Mouse (Murine) Monoclonal IL17A Primary Antibody pour ELISA, WB - ABIN2689740
Coquet, Chakravarti, Kyparissoudis, McNab, Pitt, McKenzie, Berzins, Smyth, Godfrey: Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population. dans Proceedings of the National Academy of Sciences of the United States of America 2008
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Mouse (Murine) Monoclonal IL17A Primary Antibody pour ICS, Neut - ABIN1177292
Prussin, Metcalfe: Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. dans Journal of immunological methods 1996
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Human Monoclonal IL17A Primary Antibody pour FACS - ABIN4898003
Coury, Annels, Rivollier, Olsson, Santoro, Speziani, Azocar, Flacher, Djebali, Tebib, Brytting, Egeler, Rabourdin-Combe, Henter, Arico, Delprat: Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. dans Nature medicine 2008
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Human Monoclonal IL17A Primary Antibody pour FACS - ABIN4898004
Alisa, Boswell, Pathan, Ayaru, Williams, Behboudi: Human CD4(+) T cells recognize an epitope within alpha-fetoprotein sequence and develop into TGF-beta-producing CD4(+) T cells. dans Journal of immunology (Baltimore, Md. : 1950) 2008
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Human Monoclonal IL17A Primary Antibody pour BP, FACS - ABIN4324658
Wen, Wan, Ren, Zhou, Gao, Wu, Wang, Yuan, Zhou: Potassium supplementation inhibits IL-17A production induced by salt loading in human T lymphocytes via p38/MAPK-SGK1 pathway. dans Experimental and molecular pathology 2016
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SNPs of rs3819024 in IL-17A and rs763780 in IL-17F (Montrer IL17F Anticorps) were weakly related to a prognosis of tuberculosis.
this study shows that aberrant NKG2D (Montrer KLRK1 Anticorps) expression with IL-17 production of CD4 (Montrer CD4 Anticorps)+ T subsets in patients with type 2 diabetes
Luciferase assay using the 5'-UTR (Montrer UTS2R Anticorps) of the IL-17 F gene revealed transcriptional regulation. Induced IL-17 F production was further confirmed at the protein level by ELISA. Smad1 (Montrer GARS Anticorps)/5/8 inhibitor pretreatment decreased IL-17 F expression levels in the cells.
Study shows increased IL-17A expression in early tendinopathy and proposes IL-17A as an inflammatory regulator in tendon remodeling.
Several studies identified IL-17A as a pro-inflammatory player in atherosclerosis while its expression was associated with increased inflammation and plaque vulnerability in human atherosclerotic lesions. Moreover, IL-17A induced a pro-inflammatory, pro-thrombotic, plaque-destabilizing, and cell-attracting response of the inflammatory milieu of human plaque tissue samples. [review]
asymmetric cell divisions in psoriasis are IL17A-dependent.
Serum IL-23 (Montrer IL23A Anticorps) and IL-17 levels were elevated in patients with aneurysmal subarachnoid hemorrhage (aSAH (Montrer ASAH1 Anticorps)) showing upregulation of IL-23 (Montrer IL23A Anticorps)/IL-17 inflammatory axis after aSAH (Montrer ASAH1 Anticorps). Serum IL-23 (Montrer IL23A Anticorps) and IL-17 showed differential correlations with post hemorrhagic complications and no correlation with clinical outcome.
More prominent IL-17 and IFN-gamma (Montrer IFNG Anticorps) production by all lymphocyte subsets in Behcet disease (BD) might be associated with the increased innate responses, early tissue neutrophil infiltrations and late adaptive immunity in BD.
Data showed that IL-17A levels were sustained in respiratory samples from cystic fibrosis (Montrer S100A8 Anticorps) patients infected by P. aeruginosa. IL-17 mediated-immunity plays a double-edged found during chronic airways infection: in one hand, it contributes to the control of P. aeruginosa burden, modulating host resistance, while, on the other, it alters host tolerance, propagating exacerbated pulmonary neutrophilia and tissue remodeling.
gamma delta T cells, rather than Th17cells, are the principal producers of IL-17 in acute gouty arthritis patients during the acute gout flares.
Data show increased interleukin 17 (IL-17) staining intensity in mediastinal lymph node from chronic recurrent airway obstruction (RAO (Montrer AOC2 Anticorps)) horses.
cloning and characterization of interleukin-17 expressed gene sequence from mRNA obtained from intestinal tissue and interleukin-23 expressed gene sequence from mRNA obtained from peripheral blood mononuclear cells
This study examined effects of in vitro exposure to solutions of hay (Montrer GTF2H5 Anticorps) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
IL-17A and IL-17F (Montrer IL17F Anticorps) exert distinct biological effects during pulmonary infection; the IL-17F (Montrer IL17F Anticorps)/IL-17RC (Montrer IL17RC Anticorps) signaling axis has the potential to significantly worsen pathogen-associated inflammation of the lower respiratory tract.
TLR2/4-mediated IL-17A inflammatory signaling is involved in vessel degeneration and revascularization, indicating that modulation of the TLR2/4-IL-17A pathway may be a novel therapeutic strategy for degenerative diseases.
The hormone levels are significantly reduced and lymphocytic infiltration in the lacrimal gland in ovariectomized mice, whereas the frequency of Th17 cells in the blood and spleen and IL-17A and IL-23 (Montrer IL23A Anticorps) expression in the lacrimal glands are increased, leading to reduced tear production and positive fluorescein staining in the cornea.
the results suggest that IL-17A induces podocyte injury by activating the NLRP3 (Montrer NLRP3 Anticorps) inflammasome and IL-1beta (Montrer IL1B Anticorps) secretion and contributes to disruption of the kidney's filtration system.
These results suggest that a low concentration of IL-17A is likely to promote autophagic activity via activating RANKL (Montrer TNFSF11 Anticorps)-JNK (Montrer MAPK8 Anticorps) pathway during osteoclastogenesis.
study shows that IL-17A plays an important role in comorbid depression associated with psoriatic inflammation, where both NFkappaB and p38MAPK (Montrer MAPK14 Anticorps) pathways play significant roles via upregulation of inflammatory mediators in the brain
the present study demonstrated that IL-17A crucially regulated the wound healing process and that accelerated neutrophil accumulation caused by IL-17A led to the delayed wound repair.
The results emphasize the importance of IL-17 in experimental autoimmune myasthenia gravis development and that IL-17 independent pathways drive the autoimmune reaction.
In estrogen receptor (Montrer ESR1 Anticorps) negative breast cancer cells targeting of IL-17A inhibited PDL1 (Montrer CD274 Anticorps) expression in the tumor microenvironment, decreasing the percentage of Treg cells in tumor-infiltrating lymphocytes, and promoting CD4 (Montrer CD4 Anticorps)+ and CD8 (Montrer CD8A Anticorps)+ T cells to secrete interferon gamma (Montrer IFNG Anticorps).
Report provides evidence that IL-17 can promote Lewis lung carcinoma growth through inhibition of myeloid-derived suppressor cells apoptosis, which maybe dependent on ERK1/2 signaling pathway.
calves, like humans, mount a robust IL-17 response during respiratory syncytial virus infection.
Data show that CD4 (Montrer CD4 Anticorps)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 termed Th17 and gammadelta17 cells.
IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
IL-17A and IL-17F (Montrer IL17F Anticorps) have a potential to modulate the mammary gland immune response to mastitis-causing pathogens.
The results of this study provide evidence of the role of IL-17 in the immunopathology of tuberculosis and support the use of IL-17 as a potential biomarker with predictive value of prognosis in bTB.
At week 15, skin cell infiltrates from pigs with crusted scabies had significantly higher CD8 (Montrer CD8A Anticorps)+ T cell, gammadelta T cell and IL-17+ cell numbers than those with ordinary scabies. Peripheral IL-17 levels were not increased, suggesting that localized skin IL-17-secreting T cells may play a critical role in the pathogenesis of crusted scabies development.
Alterations in the IL-17 regulated pathway of porcine colon in response to dietary supplementation with seaweeds and yeast are reported.
conclude that only two subpopulations of porcine WBCs are sources of IL-17 after non-specific stimulation: CD3 (Montrer CD3 Anticorps)(+)CD4 (Montrer CD4 Anticorps)(+) and CD3 (Montrer CD3 Anticorps)(+)gammadeltaTCR(+).
Cloning and expression of interleukin-17.
Data indicate that IL-17/22-producing cells play an important role in maintenance of intestinal mucosa in gluten-sensitive primates.
molecular cloning and expression of recombinant IL-17A; homology modeling revealed that the three-dimensional structure resembles that of human IL-17A. The secondary structure predicted showed the presence of one extra helix in the N-terminal region.
one of the interaction sites between IL17A and its receptor IL17RA (Montrer IL17RA Anticorps)
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
, cytotoxic T-lymphocyte-associated antigen 8
, cytotoxic T-lymphocyte-associated protein 8
, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
, interleukin 17
, interleukin 17A
, Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)