Large Proline-Rich Protein BAT3 Protéines (BAT3)

BAT3 was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. De plus, nous expédions Large Proline-Rich Protein BAT3 Anticorps (81) et Large Proline-Rich Protein BAT3 Kits (15) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
BAT3 224727 Q9Z1R2
BAT3 7917 P46379
Rat BAT3 BAT3 94342 Q6MG49
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Showing 6 out of 11 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Cellules d'insectes Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
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Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Souris Inconjugué   100 μg Connectez-vous pour afficher 11 to 18 Days
$582.75
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HEK-293 Cells Humain Inconjugué   100 μg Connectez-vous pour afficher 11 to 18 Days
$767.53
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BAT3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Mouse (Murine) ,

Human , ,
, ,

Plus protéines pour Large Proline-Rich Protein BAT3 (BAT3) partenaires d'interaction

Arabidopsis thaliana Large Proline-Rich Protein BAT3 (BAT3) interaction partners

  1. Arabidopsis BAG6 (AtBAG6) knockout lines exhibited a pronounced enhancement of susceptibility to the necrotrophic fungal pathogen Botrytis cinerea.

  2. Targeted inactivation of BAGP1 or APCB1 results in the blocking of BAG6 processing and loss of fungal resistance.

Mouse (Murine) Large Proline-Rich Protein BAT3 (BAT3) interaction partners

  1. BAT3 negatively regulates lipopolysaccharide-induced NF-kappaB (Montrer NFKB1 Protéines) signaling through TRAF6 (Montrer TRAF6 Protéines).

  2. The observations suggest a mechanism whereby the BAG6 ubiquitin-linked domain provides a platform for discriminating substrates with shorter hydrophobicity stretches as a signal for defective proteins.

  3. we found BAG6 to be dispensable in antigen processing

  4. Data indicate that the BAGS domain of BAG6 (Bcl-2-associated athanogene 6) interacts with the C-terminal domain of Ubl4a (ubiquitin-like protein 4a (Montrer UBL4A Protéines)).

  5. BAG6 also decreases the EP300 (Montrer EP300 Protéines) dependent-acetylation of ATG5 (Montrer ATG5 Protéines), ATG7 (Montrer ATG7 Protéines), and LC3 (Montrer MAP1LC3A Protéines)-I, posttranslational modifications that inhibit autophagy.

  6. BAT3 tightly controls autophagy by modulating p300 (Montrer NOTCH1 Protéines) intracellular localization, affecting the accessibility of p300 (Montrer NOTCH1 Protéines) to its substrates, p53 (Montrer TP53 Protéines) and ATG7 (Montrer ATG7 Protéines).

  7. Mycobacterium tuberculosis-derived protein ESAT-6 (Rv3875) induced transient increase in the expression and release of BAT3 in macrophages.

  8. Bat3 interacts with the nuclear phosphatase small C-terminal domain phosphatase (SCP) 2 (Montrer CRISP3 Protéines), which terminates BMP signaling by dephosphorylating Smad1 (Montrer SMAD1 Protéines)/5/8.

  9. Scythe is critical for viability and normal development, probably via regulation of programmed cell death and cellular proliferation

  10. Scythe regulates apoptosis-inducing factor (Montrer AIFM1 Protéines) stability during endoplasmic reticulum stress-induced apoptosis

Human Large Proline-Rich Protein BAT3 (BAT3) interaction partners

  1. The observations suggest a mechanism whereby the BAG6 ubiquitin-linked domain provides a platform for discriminating substrates with shorter hydrophobicity stretches as a signal for defective proteins.

  2. BAG6 co-localizes with HSPA2 (Montrer HSPA2 Protéines) in huinan testicular germ cells and epididymal spermatozoa, moving from the equator to the anterior head during capacitation and stably interacting with HSPA2 (Montrer HSPA2 Protéines). In zona pellucida binding defect infertility, BAG6 is lacking.

  3. we found BAG6 to be dispensable in antigen processing

  4. VNTR in the coding region of the FAM46A gene, FAM46A rs11040 SNP and BAG6 rs3117582 SNP are associated with susceptibility to tuberculosis

  5. BAG6 rs3117582 SNP was associated with non small cell lung cancer in the Norwegian subjects and the combined Croatian-Norwegian subjects corroborating the earlier finding that BAG6 rs3117582 SNP was associated with lung cancer in Europeans.

  6. The BAT2/BAT3 polymorphisms and specifically the A/C haplotype may represent a novel immunogenetic factor associated with graft rejection in patients undergoing allo-HSCT.

  7. Data show that molecular chaperone (Montrer HSP90AA1 Protéines) BAG6_ubiquitin-like domain (UBL) and ubiquitin-like 4A (Montrer UBL4A Protéines) UBL4A_UBL compete for the same binding site on N-terminal dimerisation domain of SGTA (Montrer SGTA Protéines) protein (SGTA_NT).

  8. This meta-analysis suggested that HLA-B-associated transcript 3 polymorphisms are risk factors for lung cancer.

  9. Both TRC35 (Montrer C7orf20 Protéines) and Ubl4A (Montrer UBL4A Protéines) have distinct C-terminal binding sites on Bag6 defining a minimal Bag6 complex.

  10. Exogenous BAG6 perturbs the function of the BAG6 complex at a stage subsequent to substrate recognition and polyubiquitylation, most likely the BAG6-dependent delivery of OpD (Montrer FLNA Protéines) to the proteasome.

Profil protéine Large Proline-Rich Protein BAT3 (BAT3)

Profil protéine

This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BAT3

  • BCL-2-associated athanogene 6 (BAG6)
  • BCL2-associated athanogene 6 (Bag6)
  • BCL2 associated athanogene 6 (BAG6)
  • 2410045D21Rik Protéine
  • AA408914 Protéine
  • ARABIDOPSIS THALIANA BCL-2-ASSOCIATED ATHANOGENE 6 Protéine
  • ATBAG6 Protéine
  • BAG-6 Protéine
  • BAT3 Protéine
  • BCL-2-associated athanogene 6 Protéine
  • D6S52E Protéine
  • D17H6S52E Protéine
  • G3 Protéine
  • Scythe Protéine
  • T3F17.11 Protéine

Protein level used designations for BAT3

BAG family molecular chaperone regulator 6 , HLA-B-associated transcript 3 , large proline-rich protein BAG6 , large proline-rich protein BAT3 , protein Scythe , HLA-B associated transcript 3 , HLA-B associated transcript-3 , protein G3 , scythe , Large proline-rich protein BAT3

GENE ID SPECIES
819232 Arabidopsis thaliana
224727 Mus musculus
7917 Homo sapiens
94342 Rattus norvegicus
508605 Bos taurus
474842 Canis lupus familiaris
100153950 Sus scrofa
100529065 Ornithorhynchus anatinus
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