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LCAT encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. De plus, nous expédions LCAT Anticorps (116) et LCAT Protéines (33) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 48 products:
Human LCAT Kit ELISA pour Sandwich ELISA - ABIN577492
Nakhjavani, Morteza, Karimi, Banihashmi, Esteghamati: Diabetes induces gender gap on LCAT levels and activity. dans Life sciences 2013
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Human LCAT Kit ELISA pour Sandwich ELISA - ABIN572371
Fais, Cacace, Atzori, Era, Ruggiero: Plasma phospholipase, γ-CEHC and antioxidant capacity in fibromyalgia. dans International journal of rheumatic diseases 2015
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Mouse (Murine) LCAT Kit ELISA pour Sandwich ELISA - ABIN1118150
Ahn, Jung, Kwon, Song: Alteration of Lysophosphatidylcholine-Related Metabolic Parameters in the Plasma of Mice with Experimental Sepsis. dans Inflammation 2016
data suggests a model wherein the active site of LCAT is shielded from soluble substrates by a dynamic lid until it interacts with HDL (Montrer HSD11B1 Kits ELISA) to allow transesterification to proceed
Increased LCAT activity may be associated with increased formation of triglyceride rich lipoproteins, leading to a reduction in LDL particle size and atherosclerosis.
Mapping the naturally occurring mutations onto the structure provides insight into how they may affect LCAT enzymatic activity.
Report slightly reduction in LCAT that would probably reflect a delay in reverse cholesterol transport occurring in MetS.
rs5923 polymorphism is not associated with low high-density lipoprotein cholesterol(HDL (Montrer HSD11B1 Kits ELISA)-C)levels in Iranian population
increased cholesterol esterification by LCAT is atheroprotective
The data indicate that this novel apoA-I (Montrer APOA1 Kits ELISA) missense is associated with markedly decreased levels of HDL (Montrer HSD11B1 Kits ELISA) cholesterol and very large alpha-1 HDL (Montrer HSD11B1 Kits ELISA), as well as decreased serum cellular cholesterol efflux and LCAT activity
A robust all-atom model for LCAT generated by homology modeling
This study investigated how the natural LCAT[T147I] and LCAT[P274S] mutations affect the pathway of biogenesis of high-density lipoproteins.
A synonymous H287H mutation in the coding region of exon 6 of the lecithin cholesterol acyltransferase gene was observed in an individual with HDLC levels of 75 mg/dl.
Taken together, these results suggest that apoE (Montrer APOE Kits ELISA)-containing discoidal HDLs (Montrer CSF1R Kits ELISA) do not require LCAT-dependent maturation to mediate efficient Abeta (Montrer APP Kits ELISA) clearance
Gene transfer of WT LCAT in LCAT(-/-) mice increased 11.8-fold the plasma cholesterol, whereas the LCAT[T147I] and LCAT[P274S] mutants caused a 5.2- and 2.9-fold increase, respectively.
DYRK1A (Montrer DYRK1A Kits ELISA) overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I (Montrer APOA1 Kits ELISA) levels.
adrenal glucocorticoid function in LCAT knockout (KO) mice
a novel function of apoA-IV (Montrer APOA4 Kits ELISA) in the biogenesis of discrete HDL (Montrer HSD11B1 Kits ELISA)-A-IV particles with the participation of ABCA1 (Montrer ABCA1 Kits ELISA) and LCAT
Studies suggest that absence of lecithin cholesterol acyltransferase (LCAT) may protect against insulin (Montrer INS Kits ELISA) resistance, diabetes and obesity.
Data show that LCAT activity was significantly higher in long chain base biosynthesis protein 2 (Sptlc2 (Montrer SPTLC2 Kits ELISA))+/- and sphingomyelin synthase 2 (Sms2 (Montrer SGMS2 Kits ELISA))-/- mice, but markedly lower in ApoE (Montrer APOE Kits ELISA)-/- and Ldlr (Montrer LDLR Kits ELISA)-/- mice.
LCAT deficiency confers gender-specific protection against diet-induced obesity and insulin (Montrer INS Kits ELISA) resistance at least in part through regulation in UPR, white adipose tissue adipogenesis, and brown adipocyte partitioning
Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E (Montrer APOE Kits ELISA) knockout background in association with a reduction in atherosclerosis
LCAT cholesterol esterification is associated with the increase of ApoE (Montrer APOE Kits ELISA)/ApoA-I (Montrer APOA1 Kits ELISA) ratio during atherosclerosis progression in rabbit.
The 1,434 bp mRNA sequence of porcine LCAT including the full coding region and encoding a protein of 472 amino acids, was obtained.
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.
, phospholipid-cholesterol acyltransferase
, lecithin-cholesterol acyltransferase Lcat
, lecithin-cholesterol acyltransferase
, lecithin cholesterol acyltransferase
, Lecithin-cholesterol acyltransferase