Leupaxin (LPXN) Kits ELISA

The product encoded by LPXN is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. De plus, nous expédions Leupaxin Anticorps (67) et Leupaxin Protéines (8) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
LPXN 9404 O60711
LPXN 107321 Q99N69
Anti-Rat LPXN LPXN 293783  
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Top Leupaxin Kits ELISA sur anticorps-enligne.fr

Showing 2 out of 4 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
$838.60
Détails
Souris < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
$838.60
Détails

Plus Kits ELISA pour Leupaxin partenaires d'interaction

Human Leupaxin (LPXN) interaction partners

  1. LPXN may facilitate bladder cancer progression by upregulating the expression of S100P via PI3K/AKT pathway. These results provide a novel insight into the role of LPXN in tumorigenesis and progression of bladder cancer and potential therapeutic target of bladder cancer.

  2. this is the first demonstration of a role for the leupaxin in the regulation of hepatocellular carcinoma progression, at least in part, by enhancing beta-catenin transcription activity.

  3. The full-length leupaxin binds to the Pyk2-focal adhesion targeting domain.

  4. Authors demonstrate that LPXN directly influences cytoskeletal dynamics via interaction with the actin-binding protein CaD and regulates CaD phosphorylation by recruiting ERK to highly dynamic structures within PCa cells.

  5. Results show that leupaxin has particular influence on the progression and invasion of breast cancer cells and may therefore represent an interesting candidate protein for diagnosis and therapeutic interventions.

  6. first evidence of dynamic regulation of leupaxin localization and tyrosine phosphorylation by G-Protein Coupled Receptors

  7. leupaxin functions as a paxillin counterpart that potently suppresses the tyrosine phosphorylation of paxillin during integrin signaling.

  8. leupaxin may be a critical nucleating component of the osteoclast podosomal signaling complex

  9. Leupaxin binding to tyrosine phosphatase PEP suggests that leupaxin may function as a signal-transducing complex with PEP.

  10. These data demonstrate that LPXN forms a signaling complex with Pyk2, c-Src, and PTP-PEST to regulate migration of prostate cancer cells.

  11. Leupaxin plays an inhibitory role in BCR signaling and B cell function.

  12. leupaxin could serve as a potential progression marker for a subset of PCa and may represent a novel coactivator of the androgen receptor

  13. Leupaxin is enriched in vascular smooth nuscle. It undergoes cytoplasmic/nuclear shuttling & functions as an serum response factor cofactor. It associates with CArG-containing regions. Its ectopic expression induces smooth muscle marker gene expression.

  14. LPXN, a member of the paxillin superfamily, is fused to RUNX1 in an acute myeloid leukemia patient with a t(11;21)(q12;q22) translocation.

Mouse (Murine) Leupaxin (LPXN) interaction partners

  1. leupaxin functions as a paxillin counterpart that potently suppresses the tyrosine phosphorylation of paxillin during integrin signaling.

  2. leupaxin may be a critical nucleating component of the osteoclast podosomal signaling complex

  3. Association of the scaffold protein LPXN with Src adds further complexity to the organization of the podosomal signaling complex in osteoclasts.

  4. Leupaxin plays an inhibitory role in BCR signaling and B cell function.

  5. Leupaxin is enriched in mouse vascular smooth muscle and its expression is dynamically regulated during development.

Leupaxin (LPXN) profil antigène

Antigen Summary

The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with Leupaxin (LPXN) Kits ELISA

  • leupaxin (LPXN) anticorps
  • leupaxin (Lpxn) anticorps
  • leupaxin (lpxn) anticorps
  • leupaxin (PAAG_03110) anticorps
  • hypothetical protein (PGTG_11441) anticorps
  • Leupaxin (lpxn) anticorps
  • 4933402K05Rik anticorps
  • A530083L21Rik anticorps
  • AV278559 anticorps
  • LDPL anticorps
  • MGC140379 anticorps

Protein level used designations for Leupaxin (LPXN) Kits ELISA

leupaxin , Leupaxin

GENE ID SPECIES
9404 Homo sapiens
107321 Mus musculus
293783 Rattus norvegicus
423129 Gallus gallus
451205 Pan troglodytes
483465 Canis lupus familiaris
513264 Bos taurus
560743 Danio rerio
702033 Macaca mulatta
9097993 Paracoccidioides sp. 'lutzii' Pb01
10527262 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100008712 Oryctolagus cuniculus
100066577 Equus caballus
100196515 Salmo salar
100394284 Callithrix jacchus
100445873 Pongo abelii
100592030 Nomascus leucogenys
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